???
|
|
??? ??
- ???
- 153 °C
- ?? ?
- 523.8±50.0 °C(Predicted)
- ??
- 1.33±0.1 g/cm3(Predicted)
- ?? ??
- Sealed in dry,Store in freezer, under -20°C
- ???
- DMSO: ??? ? ??
- ??? ??
- ??
- ?? ?? (pKa)
- 12.06±0.70(Predicted)
- ??
- ???
- InChIKey
- VEBVPUXQAPLADL-POYOOMFHSA-N
- SMILES
- [C@@]12(O)[C@@H](O)C(C)=C[C@@]31C(=O)[C@@]([H])(C=C(CO)[C@H]2O)[C@]1([H])C(C)(C)[C@]1([H])C[C@H]3C
??
- ?? ? ?? ??
- ?? ? ???? ?? (GHS)
| ????(GHS): |
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|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ?? ?: | Danger | |||||||||||||||||||||
| ??·?? ??: |
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| ??????: |
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??? C??? ??, ??, ??
??
Ingenol is a diterpenoid related to phorbol, derived from the milkweed plant E. peplus. It is a protein kinase C activator that displays a Ki value of 30 μM and an ED50 value of 27 μM in vitro. Most ingenol esters are tumor-??
Ingenol, is the analogue of Ingenol 3-Angelate (I655800), which has anti-tumor activity when used topically for the treatment of actinic keratosis.??
ChEBI: A tetracyclic diterpenoid that is 1a,2,5,5a,6,9,10,10a-octahydro-1H-2,8a-methanocyclopenta[a]cyclopropa[e][10]annulen-11-one substituted at positions 5, 5a and 6 by hydroxy groups, positions 1, 1, 7 and 9 by met yl groups, position 4 by a hydroxymethyl group and position 1 by an oxo group (the 1aR,2S,5R,5aR,6S,8aS,9R,10aR diastere mer).??? ?? ?? ? ???
???
1H-2,8a-Methanocyclopenta[a]cyclopropa[e]cyclodecen-11-one, 4-[(acetyloxy)methyl]-1a,2,5,5a,6,9,10,10a-octahydro-5,5a,6-trihydroxy-1,1,7,9-tetramethyl-, (1aR,2S,5R,5aR,6S,8aS,9R,10aR)-
20-??????
Ingenol mebutate
?? ??
??? ?? ??
???( 274)?? ??
| ??? | ?? | ??? | ?? | ?? ? | ?? |
|---|---|---|---|---|---|
| Chengdu Biopurify Phytochemicals Ltd. | +86-28-82633860; +8618080483897 |
sales@biopurify.com | China | 4616 | 58 |
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 |
zheyansh@163.com | CHINA | 3619 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 |
sales@coreychem.com | China | 29815 | 58 |
| NanJing Spring & Autumn Biological Engineering CO., LTD. | +8613815430202 |
sale02@cqherb.com | CHINA | 376 | 58 |
| Shanghai Standard Technology Co., Ltd. | 18502101150 |
ft-sales@nature-standard.com | CHINA | 1923 | 58 |
| Neostar United (Changzhou) Industrial Co., Ltd. | +86-0519-85551759 +8613506123987 |
marketing1@neostarunited.com | China | 8828 | 58 |
| Nanjing Sky Hope Tongyuan Biological Engineering Co., Ltd. | +86-0086-025-69916489 +86-18852044786 |
tongyuansales@vip.sina.com | China | 323 | 58 |
| Wuhan ChemNorm Biotech Co.,Ltd. | +86-27-8439 4403 18971486879 |
sales@chemnorm.com | CHINA | 2935 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 |
marketing@targetmol.com | United States | 32466 | 58 |
| Hubei Ipure Biology Co., Ltd | +8613367258412 |
ada@ipurechemical.com | China | 10236 | 58 |
??? ?? ??:
????? ?????? ?????? 3,5-????-4-???
CYCLOOCTANONE
CYCLOOCTANEMETHANOL
2,2,4-TRIMETHYL-3-PENTANONE
1-NONEN-3-OL
(R)-(-)-1-OCTEN-3-OL, 99
3-BUTENE-1,2-DIOL
ADOXAL
3,5-DIMETHYL-4-OCTANONE
2-TERT-BUTYLPROPANE-1,3-DIOL
CYCLOPROPYLACETALDEHYDE
1-HYDROXYMETHYL-3-CYCLOPENTENE
2,2-DIMETHYL-3-OCTANONE
(HYDROXYMETHYL)CYCLOHEPTANE
Ingenol