1,4-??????
1,4-?????? ??? ???
?? ??:
110-56-5
???:
1,4-??????
???(??):
1,4-????????;1,4-???????;1,4-??????;??,1,4-????-??????????
???:
1,4-Dichlorobutane
???(??):
DICHLOROBUTANE;1,4-Dichlorobu;1,4-Dichlorbutan;1,4-DICHLOROBUTANE;1,4-dichloro-butan;Cefepime Impurity 9;Butane,1,4-dichloro-;Butane, 1,4-dichloro-;1,4-Dichloro-n-butane;1,4-Dichlorobutane,97%
CBNumber:
CB4852812
???:
C4H8Cl2
??? ??:
127.01
MOL ??:
110-56-5.mol
MSDS ??:
SDS
1,4-?????? ??
???
-38 °C (lit.)
?? ?
161-163 °C (lit.)
??
1.16 g/mL at 25 °C (lit.)
???
5 hPa (20 °C)
???
n 20/D 1.454(lit.)
???
104 °F
?? ??
Store below +30°C.
???
2.4g/L
??? ??
??
??
???
??????(pH)
7.3 (H2O, 20℃)
????
1.8-8.9%(V)
???
0.24g/100mL(20℃)
BRN
635673
Henry's Law Constant
2.0×10-2 mol/(m3 Pa) at 25℃, Brockbank (2013)
Dielectric constant
9.6500000000000004
???
????. ???. ???, ????? ???? ????.
InChI
1S/C4H8Cl2/c5-3-1-2-4-6/h1-4H2
InChIKey
KJDRSWPQXHESDQ-UHFFFAOYSA-N
SMILES
ClCCCCCl
LogP
2.81
CAS ??????
110-56-5(CAS DataBase Reference)
NIST
1,4-Dichlorobutane(110-56-5)
EPA
1,4-Dichlorobutane (110-56-5)
??
?? ? ?? ??
?? ? ???? ?? (GHS)
??? ??
Xi,T,F
?? ???? ??
10-36/37/38-39/23/24/25-23/24/25-11
?????
26-36-45-36/37-16-7
????(UN No.)
UN 1993 3/PG 3
WGK ??
1
?? ?? ??
220 °C
TSCA
TSCA listed
?? ??
3
????
III
HS ??
29031980
???? ???
3 - Flammable liquids
Hazard Classifications
Aquatic Chronic 3
??
LD50 orally in Rabbit: 3420 mg/kg
???? ??
KE-10098
????(GHS):
?? ?:
Warning
??·?? ??:
??
??·?? ??
?? ??
??
?? ?
?? ??
P- ??
H226 ??? ?? ? ??
??? ??
?? 3
??
H412 ??? ??? ?? ????? ???
?? ????? ?? - ??
?? 3
P273, P501
??????:
P210 ?·???·??·????? ????? - ?? ???.
P233 ??? ??? ?????.
??? ??? ? ?? ?? ??? ???? ?????.
P240 ??? ????? ?? ? ??????.
P241 ?? ??? ??[???/??/??/...]?(?) ?????.
P242 ???? ???? ?? ??? ?????
P243 ??? ?? ??? ????.
P273 ???? ???? ???.
P280 ????/???/???/?????? ?????.
P303+P361+P353 ??(?? ????)? ??? ??? ?? ??? ??? ????? ??? ?? ????/?????.
P370+P378 ?? ? ?? ?? ?? (Section 5. ??, ??? ????? ??? ???)?(?) ?????.
P403+P235 ??? ? ?? ?? ???? ???? ?????.
P501 ...? ??? / ??? ?? ???.
NFPA 704
1,4-?????? C??? ??, ??, ??
??? ??
colourless liquid
??
Used in organic synthesis including adiponitrile. It is also used as an active pharmaceutical intermediate. 1,4-dichlorobutane (1,4-DCB) can be used as an organic solvent (O) for ion-transfer voltammetry at water (W) interface.
?? ??
Colorless mobile liquid with a mild pleasant odor.
??? ?? ??
Highly flammable. Insoluble in water.
?? ???
Halogenated aliphatic compounds, such as 1,4-Dichlorobutane, are moderately or very reactive. Reactivity generally decreases with increased degree of substitution of halogen for hydrogen atoms. Materials in this group may be incompatible with strong oxidizing and reducing agents. Also, they may be incompatible with many amines, nitrides, azo/diazo compounds, alkali metals, and epoxides. 1,4-Dichlorobutane can react vigorously with oxidizing materials.
????
ACUTE/CHRONIC HAZARDS: Irritant.
1,4-?????? ?? ?? ? ???
???
?? ??
1,4-?????? ?? ??
???( 379)?? ??
Americas 1
Belgium 3
China 268
Czech 1
Europe 3
Germany 11
India 27
Japan 6
Norway 1
Slovakia 1
South Korea 1
Switzerland 2
The Netherlands 1
Ukraine 3
United Kingdom 9
United States 41
Global 379
1,4-?????? ?? ??:
1,2-?????? ?????(2-) 1,4-?????? ?? ??? ????? ?? ???? ?? 3,4-??????????? ?? n-?? ????? 1,2,3,4,5,6-???????????? ?????? 2,3-?????? ??????(4-)????? 1,4-??????
2',4'-Dichloroacetophenone
1,2-DICHLOROTETRAFLUOROCYCLOBUT-1-ENE
1,1,2-TRICHLORO-2,3,3-TRIFLUOROCYCLOBUTANE
