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2-??-6-?????[3.4]??

2-??-6-?????[3.4]??
2-??-6-?????[3.4]?? ??? ???
?? ??:
220290-68-6
???:
2-??-6-?????[3.4]??
???(??):
2-??-6-?????[3.4]??
???:
2-oxa-6-azaspiro[3.4]octane
???(??):
2-oxa-7-azaspiro[3.4]octane;2-oxa-6-azaspiro[3.4]octane;2-Oxa-6-azaspiro[3.4]octa...;2-Oxa-6-azaspiro[3.4]octane,95%;2-Oxa-6-azaspiro[3.4]octane 96%min;2-Oxa-6-azaspiro[3.4]octane (9CI, ACI);2-oxa-6-azaspiro[3.4]octane, hemioxalate salt
CBNumber:
CB52506037
???:
C6H11NO
??? ??:
113.16
MOL ??:
220290-68-6.mol

2-??-6-?????[3.4]?? ??

?? ?
187℃
??
1.08
???
63°(145°F)
?? ??
2-8°C(protect from light)
?? ?? (pKa)
10.55±0.20(Predicted)
??
Light yellow to yellow Liquid
???
?? ?????.
InChI
InChI=1S/C6H11NO/c1-2-7-3-6(1)4-8-5-6/h7H,1-5H2
InChIKey
ZHAIMJRKJKQNQI-UHFFFAOYSA-N
SMILES
C1C2(CCNC2)CO1
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
HS ?? 29339900
????(GHS): Exclamation Mark (GHS07)
?? ?: Danger
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H227 ??? ?? ??? ?? ?? 4 ?? P210, P280, P370+P378, P403+P235,P501
H315 ??? ??? ??? ????? ?? ????? ?? 2 ?? P264, P280, P302+P352, P321,P332+P313, P362
H319 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 2A ?? P264, P280, P305+P351+P338,P337+P313P
H335 ?? ???? ??? ? ?? ?? ???? ?? - 1? ??;???? ?? ?? 3 ??
??????:
P261 ??·?·??·???·??·...·????? ??? ????.
P305+P351+P338 ?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.
P405 ???? ?????.
NFPA 704
2
2 0

2-??-6-?????[3.4]?? C??? ??, ??, ??

??

2-Oxa-6-azaspiro[3.4]octane is involved in the preparation of azaspirocycle or azetidine substituted 4-anilinoquinazoline derivatives, which exhibits epidermal growth factor receptor (EGFR) inhibitory activities.

?? ??

2-Oxa-6-Azaspiro[3.4]Octane Hydrochloride may be useful in the preparation of aminocyanopyridine derivatives for the prevention or treatment of cancer or inflammatory diseases.

2-??-6-?????[3.4]?? ?? ?? ? ???

???

?? ??


2-??-6-?????[3.4]?? ?? ??

???( 92)?? ??
??? ?? ??? ?? ?? ? ??
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2-??-6-?????[3.4]?? ?? ??:

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