1-bromodibenzo[b,d]furan is a bromine-containing heterocyclic compound that can be used as an OLED intermediate. It is involved in the preparation of a rylene ketone derivative and its electroluminescent device.
??
1-bromodibenzo[b,d]furan can be used as organic synthesis intermediates and pharmaceutical intermediates, mainly used in laboratory research and development and chemical and pharmaceutical production processes.
?? ??
1-bromodibenzo[b,d]furan can be used to prepare fluorescent markers, which play an important role in biomedical research and biological analysis. It can also be used to prepare OLED materials.
Synthesis
111 g (416 mmol) of 6ˉ-bromo-2ˉ-fluorobiphenyl-2-ol are dissolved in 21 of SeccoSolv DMF (max 0.003% of H20) and cooled to 5C. 20 g (449 mmol) of sodium hydride (60% suspension in paraffin oil) are added in portions tothis solution, and the mixture is stirred for a further 20 mm. after the addition is complete and then heated at 100C for 45 mm. After cooling, 500 ml of ethanol are slowly added to the mixture, which is then evaporated to dryness in a rotary evaporator and purified by chromatography. Yield: 90 g (367 mmol), 88.5% of theory.
![1-??????[b,d]??](CAS/GIF/50548-45-3.gif)
