ANISOMYCIN
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ANISOMYCIN ??
- ???
- 140-141 C
- ?? ?
- 408.52°C (rough estimate)
- ??
- D23 -30° (methanol)
- ??
- 1.1356 (rough estimate)
- ???
- 1.5230 (estimate)
- ???
- 87℃
- ?? ??
- Inert atmosphere,Store in freezer, under -20°C
- ???
- ???: 20mg/mL, ??, ?? ?? ??? ???
- ?? ?? (pKa)
- 7.9(at 25℃)
- ??? ??
- ??
- ??? ??
- ??? ??
- ??
- ???
- ???
- ?? 2mg/ml, DMSO? 20mg/ml, ???? 20mg/ml? ?????.
- ?? ??(λmax)
- 283nm(EtOH)(lit.)
- Merck
- 14,670
- BRN
- 20705
- ???
- ????. ?? ???? ???? ????.
- InChI
- 1S/C14H19NO4/c1-9(16)19-14-12(15-8-13(14)17)7-10-3-5-11(18-2)6-4-10/h3-6,12-15,17H,7-8H2,1-2H3/t12-,13+,14+/m1/s1
- InChIKey
- YKJYKKNCCRKFSL-RDBSUJKOSA-N
- SMILES
- COc1ccc(C[C@H]2NC[C@H](O)[C@H]2OC(C)=O)cc1
??
- ?? ? ?? ??
- ?? ? ???? ?? (GHS)
| ??? ?? | T,Xn | ||
|---|---|---|---|
| ?? ???? ?? | 25-36/37/38-20/21/22 | ||
| ????? | 45-36-26 | ||
| ????(UN No.) | UN 3462 6.1/PG 3 | ||
| WGK ?? | 3 | ||
| RTECS ?? | BZ9800000 | ||
| F ?????? | 3-10 | ||
| ?? ?? | 6.1(b) | ||
| ???? | III | ||
| HS ?? | 29419090 | ||
| ???? ??? | 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects |
||
| Hazard Classifications | Acute Tox. 3 Oral | ||
| ?? | LD50 orl-rat: 72 mg/kg ANTCAO 5,490,55 |
ANISOMYCIN C??? ??, ??, ??
??? ??
Crystalline??
Anisomycin is a phenylmethylenepyrrolidine first isolated from Streptomyces griseolus in 1954 as an antiprotozoan with antifungal activity. Anisomycin is an inhibitor of protein synthesis by binding to the 60S ribosomal subunit. Interestingly, anisomycin has found use for the induction of amnesia in animal models. More recently, anisomycin has been demonstrated to induce apoptosis, to be a selective signalling agonist, to activate mitogen-activated protein (MAP) kinases and to be immunomodulatory via its action on T cells.??
ChEBI: An antibiotic isolated from various Streptomyces species. It interferes with protein and DNA synthesis by inhibiting peptidyl transferase or the 80S ribosome system.???? ??
Protein synthesis inhibitor (blocks translation). Potent activator of stress-activated protein kinases (JNK/SAPK) and p38 MAP kinase. Acts as a potent signaling agonist to selectively elicit homologous desensitization of immediate early gene induction (c-fos, fosB, c-jun, junB and junD).Safety Profile
Poison by ingestion,intraperitoneal, subcutaneous, and intravenous routes.When heated to decomposition it emits toxic fumes ofNOx.ANISOMYCIN ?? ?? ? ???
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ANISOMYCIN ?? ??
???( 345)?? ??
| ??? | ?? | ??? | ?? | ?? ? | ?? |
|---|---|---|---|---|---|
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sale2@hbyalin.com | China | 1645 | 58 |
ANISOMYCIN ?? ??:
????3-?????????
Ciprofloxacin hydrochloride
ANISOMYCIN
(R)-3-METHOXYPYRROLIDINE
(3S,4S)-Pyrrolidine-3,4-diol
4-(4-METHOXYPHENYL)-1-BUTANOL
4-PHENYL-2-BUTYL ACETATE
3-METHOXYPYRROLIDINE
3-PHENYLPROPYL FORMATE
3-ETHOXYPYRROLIDINE
1-(4-METHOXY-PHENYL)-2-BUTANAMINE
2-BENZYLPYRROLIDINE
Benzenepentanamine
NIH 3T3 - ANISOMYCIN CONTROL LYSATE
HELA - ANISOMYCIN CONTROL LYSATE
50 MG ANISOMYCIN FROM STREPTOMYCESGRISEOLUS
NIH 3T3 AND ANISOMYCIN LYSATE
HELA AND ANISOMYCIN LYSATE