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??????????????
?????????????? ??? ???
?? ??:
423-55-2
???:
??????????????
???(??):
??????????????
???:
1-BroMoheptadecafluorooctane
???(??):
PFOB;perflubron;PERFLUOROOCTYL BROMIDE;Imagent;1-BROMOPERFLUOROOCTANE;n-Perfluorooctyl bromide;HEPTADECAFLUORO-N-OCTYL BROMIDE;TBr-8;uorooctane;long’scompound
CBNumber:
CB5409529
???:
C8BrF17
??? ??:
498.96
MOL ??:
423-55-2.mol
MSDS ??:
SDS

?????????????? ??

???
6 °C
?? ?
142 °C(lit.)
??
1.93 g/mL at 25 °C(lit.)
???
12.8-72hPa at 25-65℃
???
n20/D 1.305(lit.)
???
141-143°C
?? ??
Sealed in dry,Room Temperature
???
DMSO? ???
??? ??
?? ??
Specific Gravity
1.930
??
??~???
???
?? ???? ???? ??? ????.
Merck
14,7156
BRN
2016022
??? ?? ??
??
InChI
1S/C8BrF17/c9-7(22,23)5(18,19)3(14,15)1(10,11)2(12,13)4(16,17)6(20,21)8(24,25)26
InChIKey
WTWWXOGTJWMJHI-UHFFFAOYSA-N
SMILES
FC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)Br
LogP
6.1 at 25℃
CAS ??????
423-55-2(CAS DataBase Reference)
EPA
1-Bromoheptadecafluorooctane (423-55-2)
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
??? ?? Xi
?? ???? ?? 36/37/38
????? 26-37/39
????(UN No.) 2810
WGK ?? 3
RTECS ?? RG8700000
?? ?? ?? Irritant
?? ?? 6.1(b)
???? III
HS ?? 29037800
???? ??? 10 - Combustible liquids
Hazard Classifications Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
?? LD50 i.v. in female rats: 41 g/kg (Burgan)
????(GHS): Exclamation Mark (GHS07)
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H315 ??? ??? ??? ????? ?? ????? ?? 2 ?? P264, P280, P302+P352, P321,P332+P313, P362
H319 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 2A ?? P264, P280, P305+P351+P338,P337+P313P
H335 ?? ???? ??? ? ?? ?? ???? ?? - 1? ??;???? ?? ?? 3 ??
??????:
P305+P351+P338 ?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.
NFPA 704
0
2 0

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??? ??

clear colorless liquid

??

1-BroMoheptadecafluorooctane can be used as oxygen carrier in emulsions used as blood substitutes.

?? ??

It is physiologically inert and is useful as an X-ray contrast agent, especially for lung examinations. With its low surface tension it penetrates small spaces and evenly wets healthy lung tissue.

?? ??

1-Bromoheptadecafluorooctane (perfluorooctyl bromide) is a perfluorocarbon. Poly(ethylene glycol)ylated polyester nanocapsules of perfluorooctyl bromide were surface-decorated with a RGD (arginine-glycine-aspartic acid) peptide, were used for tumor imaging. Nanocapsules of perfluorooctyl bromide have been developed as dual contrast agent for ultrasonography and Magnetic Resonance Imaging (MRI).

Toxicity evaluation

Oral/Parenteral Toxicity: intravenous-mouse LD50 14720 mg/kg
unreported-mouse LD50 42500 mg/kg

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