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Canagliflozin-10

Canagliflozin-10 ??? ???

?? ??:: 2161394-94-9

???:: Canagliflozin-10

???(??):: Canagliflozin-10;canagliflozin impurities3;canagliflozin impurities613;Canagliflozin Furanose Form (Mixture of Anomers);D-Galactitol, 1,4-anhydro-1-C-[3-[[5-(4-fluorophenyl)-2-thienyl]methyl]-4-methylphenyl]-;(2R,3R,4R,5R)-2-((R)-1,2-dihydroxyethyl)-5-(3-((5-(4- fluorophenyl)thiophen-2-yl)methyl)-4-methylphenyl) tetrahydrofuran-3,4-diol;Canagliflozin Furanose Form (Mixture of Anomers)/D-Galactitol,1,4-anhydro-1-C-[3-[[5-(4-fluorophenyl)-2-thienyl]methyl]-4-methylphenyl]-;Canagliflozin impurity 9/(2R,3R,4R,5R)-2-((R)-1,2-dihydroxyethyl)-5-(3-((5-(4- fluorophenyl)thiophen-2-yl)methyl)-4-methylphenyl) tetrahydrofuran-3,4-diol

CBNumber:: CB54819427

???:: C24H25FO5S

??? ??:: 444.52

MOL ??:: 2161394-94-9.mol

?? ?? 26

Canagliflozin-10 ??

???: >53°C (dec)

?? ?: 673.5±55.0 °C(Predicted)

??: 1.375±0.06 g/cm3(Predicted)

?? ??: Hygroscopic, -20°C Freezer, Under inert atmosphere

???: DMSO(?? ???), ???(?? ???, ?????)

?? ?? (pKa): 13.56±0.70(Predicted)

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InChIKey: ZLPSHXQANWMHSC-HWVOYRNVNA-N

SMILES: O[C@@H]1[C@H]([C@]([H])([C@H](O)CO)OC1C1C=CC(C)=C(CC2=CC=C(C3C=CC(F)=CC=3)S2)C=1)O |&1:1,2,3,5,r|

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Canagliflozin-10 C??? ??, ??, ??

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1-C-[3-[[5-(4-Fluorophenyl)-2-thienyl]methyl]-4-methylphenyl]-D-glucose is an intermediate used in the synthesis of Canagliflozin (C175190). Canagliflozin is a sodium/glucose cotransporter 2 (SGLT2) inhibitor; Canagliflozin is a candidate for the treatment of type 2 diabetes and obesity.

Canagliflozin-10 ?? ?? ? ???

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Canagliflozin-10 ?? ??

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???	??	???	??	?? ?	??
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Canagliflozin-10 ?? ??:

Pioglitazone hydrochloride Canagliflozin Impurity 27 Canagliflozin Impurity 16 2-(5-broMo-2-Methylbenzyl)-5-phenylthiophene Canagliflozin Impurity 12 Canagliflozin Impurity 63 Canagliflozin Impurity 25 Canagliflozin heMihydrate Canagliflozin Dimer Impurity 2 Canagliflozin Impurity 15 (1R,2S,3R,4R,5R)-1-(3-((5-(4-fluorophenyl)thiophen-2-yl)Methyl)-4-Methylphenyl)hexane-1,2,3,4,5,6-hexaol Canagliflozin Impurity 20 Canagliflozin Canagliflozin Impurity 41 2-(4-fluorophenyl)-5-(2-Methylbenzyl)thiophene Canagliflozin Impurity 45 2-(1,2-dihydroxyethyl)-5-(3-((5-(4-fluorophenyl)thiophen-2-yl)Methyl)-4-Methylphenyl)tetrahydrofuran-3,4-diol Canagliflozin D4

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