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SNAP

SNAP ??? ???
?? ??:
79032-48-7
???:
SNAP
???(??):
S-NITROSO-N-ACETYLPENICILLAMINE;SNAP;SNAP(D);S-Nitroso-acetyl penicillamine;N-ACETYL-3-(NITROSOTHIO)-D-VALINE;N-Acetyl-S-nitroso-D-penicillaMine;S-NITRO-N-ACETYL-D,L-PENACILLAMINE;S-nitroso-N-acetyl-D-penicillamine;D-Valine, N-acetyl-3-(nitrosothio)-;S-Nitroso-N-acetyl-D-b,b-dimethylcysteine
CBNumber:
CB5736261
???:
C7H12N2O4S
??? ??:
220.25
MOL ??:
79032-48-7.mol
MSDS ??:
SDS

SNAP ??

??
1.36±0.1 g/cm3(Predicted)
?? ??
−20°C
???
H2O: ≥2 mg/mL
??? ??
??
?? ?? (pKa)
3.06±0.10(Predicted)
??
??
InChI
1S/C7H12N2O4S/c1-4(10)8-5(6(11)12)7(2,3)14-9-13/h5H,1-3H3,(H,8,10)(H,11,12)
InChIKey
ZIIQCSMRQKCOCT-UHFFFAOYSA-N
SMILES
S(N=O)C(C(NC(=O)C)C(=O)O)(C)C

??

??? ?? Xi
?? ???? ?? 36/37/38
????? 26-36
WGK ?? 3
???? ??? 11 - Combustible Solids

SNAP C??? ??, ??, ??

??? ??

Green Crystalline Solid

??

ChEBI: A nitroso compound that is N-acetyl-D-penicillamine in which the sulfanyl hydrogen is replaced by a nitroso group.

?? ??

Nitric oxide donor that begins to evolve nitric oxide immediately upon solubilization in aqueous buffers (t1/2 = 10 h). Mimics the actions of nitric oxide, including the relaxation of isolated bovine coronary artery rings (EC50 = 130 nM). Markedly activates soluble guanylate cyclase. Also reported to cause the reversible inactivation of protein kinase C activity. Induces apoptosis in mouse thymocytes. Note: 1 set = 4 x 5 mg.

???? ??

A stable analog of endogenous S-nitroso compounds. A source of NO in vivo which unlike organic O-nitrates does not induce tolerance. Decomposes slowly in solution with a t of 37h.

SNAP ?? ?? ? ???

???

?? ??


SNAP ?? ??

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