Isopropyl 2-cyanoacetate
Isopropyl 2-cyanoacetate ??
- ?? ?
- 207 °C(lit.)
- ??
- 1.013 g/mL at 20 °C(lit.)
- ???
- n20/D 1.416
- ???
- 99°C
- ?? ??
- Storage temp. 2-8°C
- ?? ?? (pKa)
- 2.90±0.10(Predicted)
- ??? ??
- ??? ??
- Specific Gravity
- 1.01 (20/4℃)
- ??
- ?? ?? ?? ??
- ???
- ?? ?? ?????.
- BRN
- 1756014
- CAS ??????
- 13361-30-3(CAS DataBase Reference)
??
- ?? ? ?? ??
- ?? ? ???? ?? (GHS)
| ??? ?? |
Xi |
|
|
| ?? ???? ?? |
36/37/38 |
|
|
| ????? |
23-24/25-36/37/39-26-37 |
|
|
| WGK ?? |
2 |
|
|
| RTECS ?? |
AG4270000 |
|
|
| HS ?? |
29269090 |
|
|
| ?? |
mouse,LD50,oral,4960mg/kg (4960mg/kg),BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY),Personal Communication from LONZA Ltd., CH-4002, Basel, SwitzerlandVol. 13FEB1981, |
|
|
| ????(GHS): |
|
| ?? ?: |
Warning |
| ??·?? ??: |
| ?? |
??·?? ?? |
?? ?? |
?? |
?? ? |
?? ?? |
P- ?? |
| H227 |
??? ?? |
??? ?? |
?? 4 |
?? |
|
P210, P280, P370+P378, P403+P235,P501 |
| H303 |
??? ??? ? ?? |
?? ?? ?? - ?? |
?? 5 |
|
|
P312 |
| H315 |
??? ??? ??? |
????? ?? ????? |
?? 2 |
?? |
|
P264, P280, P302+P352, P321,P332+P313, P362 |
| H319 |
?? ?? ??? ??? |
?? ? ?? ?? ??? ?? |
?? 2A |
?? |
|
P264, P280, P305+P351+P338,P337+P313P |
| H335 |
?? ???? ??? ? ?? |
?? ???? ?? - 1? ??;???? ?? |
?? 3 |
?? |
|
|
|
| ??????: |
| P261 |
??·?·??·???·??·...·????? ??? ????. |
| P264 |
?? ??? ?? ??? ????. |
| P264 |
?? ??? ?? ??? ????. |
| P280 |
????/???/???/?????? ?????. |
| P305+P351+P338 |
?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????. |
| P405 |
???? ?????. |
|
| NFPA 704 |
|
|
|
Isopropyl 2-cyanoacetate C??? ??, ??, ??
??
Isopropyl cyanoacetate was used in the synthesis of 3-substituted coumarins by undergoing Knevenagel reactions with aldehydes and ketones.
Synthesis Reference(s)
Synthesis, p. 138, 1982
DOI: 10.1055/s-1982-29718
Isopropyl 2-cyanoacetate ?? ?? ? ???
???
?? ??
Isopropyl 2-cyanoacetate ?? ??
???( 158)?? ??
Isopropyl 2-cyanoacetate ?? ??:
