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1374248-77-7
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???(??):
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???:
Ubrogepant
???(??):
MK-1602;(S)-N-((3S,5S,6R)-6-methyl-2-oxo-5-phenyl-1-(2,2,2-trifluoroethyl)piperidin-3-yl)-2'-oxo-1',2',5,7-tetrahydrospiro[cyclopenta[b]pyridine-6,3'-pyrrolo[2,3-b]pyridine]-3-carboxamide;Ubuzhipan;Ubrogepant;Ubrogepant D5;Ubrogepant API;MK-1602 Ubrogepant;Ubrogepant, 10 mM in DMSO;MK1602,MK 1602,Ubrogepant,inhibit,Inhibitor,Calcitonin gene-related peptide receptor,CGRP Receptor;Spiro[6H-cyclopenta[b]pyridine-6,3'-[3H]pyrrolo[2,3-b]pyridine]-3-carboxamide, 1',2',5,7-tetrahydro-N-[(3S,5S,6R)-6-methyl-2-oxo-5-phenyl-1-(2,2,2-trifluoroethyl)-3-piperidinyl]-2'-oxo-, (3'S)-
CBNumber:
CB62708849
???:
C29H26F3N5O3
??? ??:
549.54
MOL ??:
1374248-77-7.mol

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?? ?
729.4±60.0 °C(Predicted)
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1.45±0.1 g/cm3(Predicted)
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Store at -20°C
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DMSO? ???
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Solid
?? ?? (pKa)
11.08±0.20(Predicted)
??
White to off-white
InChIKey
DDOOFTLHJSMHLN-ZQHRPCGSSA-N
SMILES
C12C[C@@]3(C(=O)NC4=NC=CC=C43)CC1=CC(C(N[C@H]1C[C@@H](C3=CC=CC=C3)[C@@H](C)N(CC(F)(F)F)C1=O)=O)=CN=2

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Ubrogepant, is a new drug possible used for the treatment of migraine.

Synthesis

Synthesis route of Ubrogepant
Ubrogepant synthesis

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