ChemicalBook >?? ???? >API>??? ??>? ??? ?>1-(4-Cyano-4-(4-fluorophenyl)cyclohexyl)-3-methyl-4-phenylpiperidine-4-carboxylic acid monohydrochloride

1-(4-Cyano-4-(4-fluorophenyl)cyclohexyl)-3-methyl-4-phenylpiperidine-4-carboxylic acid monohydrochloride

1-(4-Cyano-4-(4-fluorophenyl)cyclohexyl)-3-methyl-4-phenylpiperidine-4-carboxylic acid monohydrochloride ??? ???

?? ??:: 79547-78-7

???:: 1-(4-Cyano-4-(4-fluorophenyl)cyclohexyl)-3-methyl-4-phenylpiperidine-4-carboxylic acid monohydrochloride

???(??):: LEVOCABASTINE HYDROCHLORIDE;547;LEVOCABASTINE HCL;R50547;LEVOSTIN;LEVOPHTA;LIVOSTIN;Unii-124xma6yei;(3S,4R)-Cabastine;LIVOSTIN USP/EP/BP

CBNumber:: CB6411376

???:: C26H30ClFN2O2

??? ??:: 456.99

MOL ??:: 79547-78-7.mol

MSDS ??:: SDS

?? ?? 95

1-(4-Cyano-4-(4-fluorophenyl)cyclohexyl)-3-methyl-4-phenylpiperidine-4-carboxylic acid monohydrochloride ??

?? ??: 2-8°C

???: DMSO: ~10mg/mL, ???

??? ??: ??

??? ??: ??? ??

??: ???

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InChIKey: OICFWWJHIMKBCD-VALQNVSPSA-N

SMILES: Cl[H].C[C@@H]1CN(CC[C@]1(C(O)=O)c2ccccc2)[C@@H]3CC[C@@](CC3)(C#N)c4ccc(F)cc4

?? ? ?? ??
?? ? ???? ?? (GHS)

??? ??	Xi
?? ???? ??	36/37/38
?????	26-36
WGK ??	3
HS ??	2933399090
???? ???	11 - Combustible Solids
Hazard Classifications	Eye Irrit. 2 Skin Irrit. 2 STOT SE 3

????(GHS):

?? ?:

Warning

??·?? ??:

??	??·?? ??	?? ??	??	?? ?	P- ??
H315	??? ??? ???	????? ?? ?????	?? 2	??	P264, P280, P302+P352, P321,P332+P313, P362
H319	?? ?? ??? ???	?? ? ?? ?? ??? ??	?? 2A	??	P264, P280, P305+P351+P338,P337+P313P
H335	?? ???? ??? ? ??	?? ???? ?? - 1? ??;???? ??	?? 3	??

??????:

P261	??·?·??·???·??·...·????? ??? ????.
P264	?? ??? ?? ??? ????.
P264	?? ??? ?? ??? ????.
P271	?? ?? ??? ? ?? ???? ?????.
P280	????/???/???/?????? ?????.
P302+P352	??? ??? ??? ?? ????.
P305+P351+P338	?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.

NFPA 704

	0
2		0

1-(4-Cyano-4-(4-fluorophenyl)cyclohexyl)-3-methyl-4-phenylpiperidine-4-carboxylic acid monohydrochloride C??? ??, ??, ??

??

Levocabastine hydrochloride is a new, highly potent and specific histamine HI-receptor antagonist without anticholinergic or antiserotonergic side effects. It is reported to have both a fast onset and long duration of action. Indications are the treatment of allergic conjunctivitis and allergic rhinitis.

??? ??

White or almost white powder.

1-(4-Cyano-4-(4-fluorophenyl)cyclohexyl)-3-methyl-4-phenylpiperidine-4-carboxylic acid monohydrochloride ?? ?? ? ???

???

?????? ??? ??? ??????????

?? ??

1-(4-Cyano-4-(4-fluorophenyl)cyclohexyl)-3-methyl-4-phenylpiperidine-4-carboxylic acid monohydrochloride ?? ??

???( 95)?? ??

???	??	???	??	?? ?	??
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1-(4-Cyano-4-(4-fluorophenyl)cyclohexyl)-3-methyl-4-phenylpiperidine-4-carboxylic acid monohydrochloride ?? ??:

AMTHAMINE DIHYDROBROMIDE Levomepromazine hydrochloride Cyclohexanol TRIS(PENTAFLUOROPHENYL)PHOSPHINE 2-FLUOROPHENYL CYCLOPENTYL KETONE Azelastine hydrochloride Astemizole Ketotifen fumarate Levamisole hydrochloride Levocetirizine dihydrochloride 6-[2-(4-IMIDAZOLYL)ETHYLAMINO]-N-(4-TRIFLUOROMETHYLPHENYL)HEPTANECARBOXAMIDE DIMALEATE thioperamide maleate salt (R)-(-)-α-Methylhistamine dihydrobromide 1-(4-FLUOROPHENYL)CYCLOHEXANECARBONITRILE 1-(4-Cyano-4-(4-fluorophenyl)cyclohexyl)-3-methyl-4-phenylpiperidine-4-carboxylic acid monohydrochloride LEVOCABASTINE 1-ISOPROPYL-PIPERIDINE-4-CARBOXYLIC ACID HYDROCHLORIDE 4-PHENYL-4-PIPERIDINE CARBOXYLIC ACID

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