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2-Chloro-5-fluoronicotinic acid

2-Chloro-5-fluoronicotinic acid ??? ???
?? ??:
38186-88-8
???:
2-Chloro-5-fluoronicotinic acid
???(??):
2-chloro-5-fluoronicotinic;2-Chloro-5-FluoronicotinicAci;2-CHLORO-5-FLUORONICOTINIC ACID;2-chloro -5-fluorinenicotinic acid;2--5-fluorinechlorinenicotinic acid;2-Chloro-5-fluoronicotinic acid 98%;2-Chloro-5-fluoronicotinic acid ,98%;2-Chloro-5-fluoropyridin-3-carboxylic acid;2-CHLORO-5-FLUOROPYRIDINE-3-CARBOXYLIC ACID;3-Pyridinecarboxylic acid, 2-chloro-5-fluoro-
CBNumber:
CB6485557
???:
C6H3ClFNO2
??? ??:
175.54
MOL ??:
38186-88-8.mol

2-Chloro-5-fluoronicotinic acid ??

???
141-142°C
?? ?
297.0±35.0 °C(Predicted)
??
1.576±0.06 g/cm3(Predicted)
?? ??
under inert gas (nitrogen or Argon) at 2-8°C
??? ??
??
?? ?? (pKa)
1.67±0.25(Predicted)
??
???
InChI
InChI=1S/C6H3ClFNO2/c7-5-4(6(10)11)1-3(8)2-9-5/h1-2H,(H,10,11)
InChIKey
WMADTZFXZAITIR-UHFFFAOYSA-N
SMILES
C1(Cl)=NC=C(F)C=C1C(O)=O
CAS ??????
38186-88-8(CAS DataBase Reference)
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
??? ?? Xi
?? ???? ?? 36/37/38
????? 7/9-24/25-26-36/37-38-51
WGK ?? 3
?? ?? IRRITANT
HS ?? 2933399990
???? ??? 11 - Combustible Solids
Hazard Classifications Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
????(GHS): Exclamation Mark (GHS07)
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H315 ??? ??? ??? ????? ?? ????? ?? 2 ?? P264, P280, P302+P352, P321,P332+P313, P362
H319 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 2A ?? P264, P280, P305+P351+P338,P337+P313P
H335 ?? ???? ??? ? ?? ?? ???? ?? - 1? ??;???? ?? ?? 3 ??
??????:
P261 ??·?·??·???·??·...·????? ??? ????.
P264 ?? ??? ?? ??? ????.
P264 ?? ??? ?? ??? ????.
P271 ?? ?? ??? ? ?? ???? ?????.
P280 ????/???/???/?????? ?????.
P302+P352 ??? ??? ??? ?? ????.
P305+P351+P338 ?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.

2-Chloro-5-fluoronicotinic acid C??? ??, ??, ??

Synthesis Reference(s)

The Journal of Organic Chemistry, 71, p. 4021, 2006 DOI: 10.1021/jo0602571

2-Chloro-5-fluoronicotinic acid ?? ?? ? ???

???

?? ??


2-Chloro-5-fluoronicotinic acid ?? ??

???( 267)?? ??
??? ?? ??? ?? ?? ? ??
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2-Chloro-5-fluoronicotinic acid ?? ??:

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