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4-CHLORO-1-NAPHTHOL

4-CHLORO-1-NAPHTHOL ??? ???
?? ??:
604-44-4
???:
4-CHLORO-1-NAPHTHOL
???(??):
4-chloronaphthalen-1-ol;4-CN;4C1N;4CN PLUS;NSC 44345;4C1N/4-CN;CHLORONAPTHOL;CHLORONAPHTHOL;Chloro-1-naphthol;Naphthol Impurity
CBNumber:
CB6715043
???:
C10H7ClO
??? ??:
178.62
MOL ??:
604-44-4.mol
MSDS ??:
SDS

4-CHLORO-1-NAPHTHOL ??

???
118-121 °C(lit.)
?? ?
254.41°C (rough estimate)
??
density
???
1.4575 (estimate)
???
73 °C
?? ??
-20°C
???
???: 50 mg/mL, ???? ???? ?? ??? ???
?? ?? (pKa)
9.11±0.40(Predicted)
??? ??
??(? ~32mg)
??
???? ??, ?? ????
BRN
509750
InChI
InChI=1S/C10H7ClO/c11-9-5-6-10(12)8-4-2-1-3-7(8)9/h1-6,12H
InChIKey
LVSPDZAGCBEQAV-UHFFFAOYSA-N
SMILES
C1(O)=C2C(C=CC=C2)=C(Cl)C=C1
CAS ??????
604-44-4(CAS DataBase Reference)
EPA
1-Naphthalenol, 4-chloro- (604-44-4)
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
??? ?? Xi,T
?? ???? ?? 36/37/38-39/23/24/25-20/21/22
????? 26-36-45-36/37
????(UN No.) UN 2810 6.1/PG 3
WGK ?? 3
F ?????? 8-9-23
TSCA TSCA listed
HS ?? 29081990
???? ??? 11 - Combustible Solids
????(GHS): Exclamation Mark (GHS07)
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H315 ??? ??? ??? ????? ?? ????? ?? 2 ?? P264, P280, P302+P352, P321,P332+P313, P362
H319 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 2A ?? P264, P280, P305+P351+P338,P337+P313P
H335 ?? ???? ??? ? ?? ?? ???? ?? - 1? ??;???? ?? ?? 3 ??
??????:
P261 ??·?·??·???·??·...·????? ??? ????.
P264 ?? ??? ?? ??? ????.
P264 ?? ??? ?? ??? ????.
P280 ????/???/???/?????? ?????.
P304+P340 ???? ??? ??? ?? ??? ??? ???? ?? ??? ??? ????.
P305+P351+P338 ?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.
P405 ???? ?????.
NFPA 704
0
2 0

4-CHLORO-1-NAPHTHOL C??? ??, ??, ??

??? ??

Off white to tan crystals

??

4-Chloro-1-naphthol has been used to visualize protein bands in western blotting. It has also been used in staining polyvinylidene fluoride (PVDF) membrane by Nakane method.

?? ??

4-Chloro-1-naphthol is primarily used for the detection of proteins, it gives a characteristic purple precipitate and the reactions are easily controllable. It can be used as a substitute for benzidine compounds, which are considered to be carcinogenic.

Purification Methods

Crystallise the naphthol from EtOH or CHCl3. [Beilstein 6 H 611, 6 II 582, 6 III 2933, 6 IV 4233.]

4-CHLORO-1-NAPHTHOL ?? ?? ? ???

???

?? ??


4-CHLORO-1-NAPHTHOL ?? ??

???( 250)?? ??
??? ?? ??? ?? ?? ? ??
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4-CHLORO-1-NAPHTHOL ?? ??:

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