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N,N-????????? N-???

N,N-????????? N-???
N,N-????????? N-??? ??? ???
?? ??:
1643-20-5
???:
N,N-????????? N-???
???(??):
N,N-?????????N-???;N,N-?????????N-???;????????;1-?????, N,N-????-, N-????;N,N-????-1-????? N-????;N,N-????-1-?????, N-????;N,N-????????? N-????;N,N-???????-1-?? ????;????????? ????;???? ????;?? ?????? ????;???????? ????
???:
LDAO
???(??):
LAURAMINE OXIDE;DDAO;OB-2;LAURYLDIMETHYLAMINE OXIDE;LAURYLDIMETHYLAMINE N-OXIDE;LADO;N,N-DIMETHYLDODECYLAMINE-N-OXIDE;N,N-dimethyldodecan-1-amine oxide;Dodecycldimethylamine oxide;dimethyldodecylamine-n-oxide
CBNumber:
CB6725905
???:
C14H31NO
??? ??:
229.4
MOL ??:
1643-20-5.mol
MSDS ??:
SDS

N,N-????????? N-??? ??

???
132-133 °C(lit.)
?? ?
371.32°C (rough estimate)
??
0.996 g/mL at 20 °C
???
0Pa at 25℃
???
n20/D 1.378
???
113°C (closed cup)(235
?? ??
-20°C
???
Ethanol:15.0(Max Conc. mg/mL);65.38(Max Conc. mM)
DMF:3.0(Max Conc. mg/mL);1.31(Max Conc. mM)
DMSO:0.1(Max Conc. mg/mL);0.44(Max Conc. mM)
PBS (pH 7.2):0.1(Max Conc. mg/mL);0.44(Max Conc. mM)
??? ??
??? ??
?? ?? (pKa)
4.79±0.40(Predicted)
Specific Gravity
0.97
??
White to off-white
??????(pH)
7.0-9.0 (25°C, 0.1M in H2O)
???
?? ???.
??
Hygroscopic
BRN
1769927
Henry's Law Constant
1.5×105 mol/(m3Pa) at 25℃, HSDB (2015)
???
????. ?? ???? ???? ????. ?? ??.
??? ?? ??
???
????? - ??
??
?? ????
?????
????? - ?? ???
????? - ???????
?? ??
??? ?? ??
LDAO (1643-20-5)
InChI
1S/C14H31NO/c1-4-5-6-7-8-9-10-11-12-13-14-15(2,3)16/h4-14H2,1-3H3
InChIKey
SYELZBGXAIXKHU-UHFFFAOYSA-N
SMILES
CCCCCCCCCCCC[N+](C)([O-])C
LogP
1.85 at 20℃
EPA
Lauryldimethylamine oxide (1643-20-5)
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
??? ?? C
?? ???? ?? 34-52/53
????? 26-36/37/39-45-27
????(UN No.) UN 3259 8/PG 2
WGK ?? 2
RTECS ?? JR6650000
F ?????? 3-10
TSCA TSCA listed
?? ?? 8
???? III
HS ?? 29299090
???? ??? 11 - Combustible Solids
Hazard Classifications Acute Tox. 4 Oral
Aquatic Acute 1
Aquatic Chronic 2
Eye Dam. 1
Skin Irrit. 2
?? ?? ??? 1643-20-5(Hazardous Substances Data)
?? mouse,LD50,intraperitoneal,375mg/kg (375mg/kg),French Medicament Patent Document. Vol. #4264M,
???? ?? KE-11348
????(GHS): Corrosion (GHS05)Exclamation Mark (GHS07)Environment (GHS09)
?? ?: Danger
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H302 ??? ??? ?? ?? ?? - ?? ?? 4 ?? P264, P270, P301+P312, P330, P501
H315 ??? ??? ??? ????? ?? ????? ?? 2 ?? P264, P280, P302+P352, P321,P332+P313, P362
H318 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 1 ?? P280, P305+P351+P338, P310
H410 ??? ??? ?? ????? ?? ??? ?? ????? ?? - ?? ?? 1 ?? P273, P391, P501
??????:
P264 ?? ??? ?? ??? ????.
P264 ?? ??? ?? ??? ????.
P273 ???? ???? ???.
P280 ????/???/???/?????? ?????.
P301+P312 ??? ???? ??? ????(??)? ??? ????.
P302+P352 ??? ??? ??? ?? ????.
P305+P351+P338 ?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.
NFPA 704
0
3 1

N,N-????????? N-??? C??? ??, ??, ??

??? ??

Clear yellow Liquid

??

LDAO is suitable to use in crystallization of membrane proteins. It is also suitable to enhance the detection of high molecular weight proteins.

?? ??

Lauryldimethylamine oxide(LDAO) is mainly used in cosmetic and personal care product formulations, particularly in hair care products as a foaming agent, fragrance ingredient, viscosity builder, stabiliser, conditioner, emulsifier, wetting agent and antistatic agent. It is also a biochemical reagent and can be used as a biological material or organic compound for life science related research.

?? ??

Crystalline solid.

??? ?? ??

Hygroscopic .

?? ???

LDAO is less basic than the tertiary amine from which LDAO is derived, but still reacts with strong acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.

????

Flash point data for LDAO are not available. LDAO is probably nonflammable.

Purification Methods

Crystallise the oxide from acetone or ethyl acetate. [Bunton et al. J Org Chem 52 3832 1987, Beilstein 4 III 410, 4 IV 798.]

N,N-????????? N-??? ?? ?? ? ???

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N,N-????????? N-??? ?? ??

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