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O-(4-hydroxy-3-iodophenyl)-3-iodo-L-tyrosine

O-(4-hydroxy-3-iodophenyl)-3-iodo-L-tyrosine ??? ???
?? ??:
4604-41-5
???:
O-(4-hydroxy-3-iodophenyl)-3-iodo-L-tyrosine
???(??):
3,3'-Diiodo-L-thyronine;3,3'-L-Diiodothyronine;L-3,3'-Diiodothyronine;Levothyroxine EP Imp J;Levothyroxine Impurity J;Levothyroxine EP Impurity J;3,5-Diiodo-L-tyrosinedihydrae;3,3’-Diiodo-L-thyronine (>97%);3,3'-Diiodo-L-thyronine - [D72021];O-(4-hydroxy-3-iodophenyl)-3-iodo-L-tyrosine
CBNumber:
CB6930097
???:
C15H13I2NO4
??? ??:
525.08
MOL ??:
4604-41-5.mol

O-(4-hydroxy-3-iodophenyl)-3-iodo-L-tyrosine ??

???
178-180°C
?? ?
520.7±50.0 °C(Predicted)
??
2.095±0.06 g/cm3(Predicted)
?? ??
Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
???
???? ??? ???(?? ???)
??? ??
??
??? ??
??? ??
?? ?? (pKa)
2.17±0.20(Predicted)
??
???? ?????
???
???
InChI
InChI=1S/C15H13I2NO4/c16-10-7-9(2-3-13(10)19)22-14-4-1-8(5-11(14)17)6-12(18)15(20)21/h1-5,7,12,19H,6,18H2,(H,20,21)/t12-/m0/s1
InChIKey
CPCJBZABTUOGNM-LBPRGKRZSA-N
SMILES
C(O)(=O)[C@H](CC1=CC=C(OC2=CC=C(O)C(I)=C2)C(I)=C1)N
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
WGK ?? 3
???? ??? 11 - Combustible Solids
????(GHS): Exclamation Mark (GHS07)
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H302 ??? ??? ?? ?? ?? - ?? ?? 4 ?? P264, P270, P301+P312, P330, P501
H315 ??? ??? ??? ????? ?? ????? ?? 2 ?? P264, P280, P302+P352, P321,P332+P313, P362
H319 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 2A ?? P264, P280, P305+P351+P338,P337+P313P
H335 ?? ???? ??? ? ?? ?? ???? ?? - 1? ??;???? ?? ?? 3 ??
??????:
P261 ??·?·??·???·??·...·????? ??? ????.
P305+P351+P338 ?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.
NFPA 704
0
2 0

O-(4-hydroxy-3-iodophenyl)-3-iodo-L-tyrosine C??? ??, ??, ??

??

3,3''-Diiodo-L-thyronine is a metabolite of thyroid hormone that is also known as T2 or 3,3’-T2. It is derived enzymatically from triiodothyronine isoforms T3 and reverse T3. T2 and its analog 3,5-T2 stimulate the activity of cytochrome c oxidase by blocking inhibition by ATP.

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Off-White Powder

O-(4-hydroxy-3-iodophenyl)-3-iodo-L-tyrosine ?? ?? ? ???

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O-(4-hydroxy-3-iodophenyl)-3-iodo-L-tyrosine ?? ??

???( 150)?? ??
??? ?? ??? ?? ?? ? ??
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O-(4-hydroxy-3-iodophenyl)-3-iodo-L-tyrosine ?? ??:

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