ChemicalBook >?? ???? >Trolox
Trolox
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Trolox ??
- ???
- 187-189 °C (lit.)
- ?? ?
- 313.42°C (rough estimate)
- ??
- 1.0616 (rough estimate)
- ???
- 1.4970 (estimate)
- ?? ??
- 2-8°C
- ???
- DMSO(?? 25mg/ml) ?? ???(?? 25mg/ml)? ?????. ?? ???? pH??? ?? ?????.
- ??? ??
- ??? ??
- ?? ?? (pKa)
- 3.35±0.20(Predicted)
- ??
- ???? ??? ????
- ???
- water: 0.5mg/mL (slightly soluble)
ethanol: 150mg/mL
methanol: soluble
- BRN
- 1384051
- ???
- ??? ?? ?????? 1? ?? ??????. DMSO ?? ??? ??? -20°?? ?? 1?? ?? ??? ? ????.
- ??? ?? ??
- ?? ????
- InChI
- InChI=1S/C14H18O4/c1-7-8(2)12-10(9(3)11(7)15)5-6-14(4,18-12)13(16)17/h15H,5-6H2,1-4H3,(H,16,17)
- InChIKey
- GLEVLJDDWXEYCO-UHFFFAOYSA-N
- SMILES
- C1(C)(C(O)=O)OC2=C(C)C(C)=C(O)C(C)=C2CC1
- CAS ??????
- 53188-07-1(CAS DataBase Reference)
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- ?? ? ?? ??
- ?? ? ???? ?? (GHS)
| ??? ?? | Xi | ||
|---|---|---|---|
| ?? ???? ?? | 36/37/38 | ||
| ????? | 26-36 | ||
| WGK ?? | 2 | ||
| RTECS ?? | DJ2273000 | ||
| TSCA | TSCA listed | ||
| HS ?? | 29339900 | ||
| ???? ??? | 11 - Combustible Solids | ||
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 |
Trolox C??? ??, ??, ??
??? ??
white to fainly beige crystalline powder??
ChEBI: A chromanol that is 6-hydroxychromane which is substituted by a carboxy group at position 2 and by methyl groups at positions 2, 5, 7, and 8. A cell-permeable, water-soluble analogue of vitamin E, it is used as a standard for measuring the antioxidant capa ity of complex mixtures.?? ??
(±)-6-Hydroxy-2,5,7,8-tetramethylchromane-2-carboxylic acid (Trolox) exhibits radical scavenging and antioxidant activities.Mechanism of action
Trolox can protect against oxidative stress, genotoxicity and inflammation induced by CS through ROS scavenging mechanism, and serve as a potential antioxidant prevention strategy against oxidative injury of ATII cells in CS-related lung diseases.Trolox ?? ?? ? ???
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2H-1-Benzopyran-2-carboxylic acid, 3,4-dihydro-6-hydroxy-2,5,7,8-tetramethyl-, methyl ester
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Trolox ?? ??
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Trolox ?? ??:
????? ??? ?????? 2-??-2-????, ??????-4,7-???-1H-??-5-? ??? ??????? ???????? N-?? ??????? ?? ??????? ???????? ???????? ??????
6-Hydroxypicolinic acid
tert-butyl 6-hydroxy-2-azaspiro[3.3]heptane-2-carboxylate
2-(Perfluorohexyl)ethyl methacrylate
Trolox
(R)-(+)-6-HYDROXY-2,5,7,8-TETRAMETHYLCHROMAN-2-CARBOXYLIC ACID
Succinimidyl (2R)-6-(Tetrahydro-2H-pyran-2-yloxy)-2,5,7,8-tetramethylchroman-2-carboxylate
(S)-(-)-6-HYDROXY-2,5,7,8-TETRAMETHYLCHROMAN-2-CARBOXYLIC ACID
(R)-6-METHOXY-2,5,7,8-TETRAMETHYLCHROMANE-2-CARBOXYLIC ACID
(S)-6-METHOXY-2,5,7,8-TETRAMETHYLCHROMANE-2-CARBOXYLIC ACID
6-HYDROXY-2,5,7,8-TETRAMETHYLCHROMAN-2-CARBOXYLIC ACID
6-METHOXY-2,5,7,8-TETRAMETHYL-CHROMAN-2-CARBOXYLIC ACID METHYL ESTER