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ChemicalBook >?? ???? >?????????B(50mg)(5-(4-?????)-2-??????-(2-??????)??????)

?????????B(50mg)(5-(4-?????)-2-??????-(2-??????)??????)

?????????B(50mg)(5-(4-?????)-2-??????-(2-??????)??????) ??? ???

?? ??:: 57268-33-4

???:: ?????????B(50mg)(5-(4-?????)-2-??????-(2-??????)??????)

???(??):: ?????????B(50mg)(5-(4-?????)-2-??????-(2-??????)??????)

???:: Dantrolene Related Compound B (50 mg) (5-(4-nitrophenyl)-2-furaldehyde-(2-carboxymethyl) semicarbazone)

???(??):: DANTROLENE RC B;Dantrolene USP RC B;Dantrolene Impurity 2;Dantrolene impurity B;Dantrolene EP Impurity B;Dantrolene Related CoMpound B;Dantrolene USP Related Compound B;5-(4-Nitrophenyl)-2-furaldehyde-(2-carboxyMethyl) SeMicarbazone;N-carbamoyl-N-(((5-(4-nitrophenyl)furan-2-yl)methylene)amino)glycine;[(Aminocarbonyl)[[5-(4-nitrophenyl)-2-furanyl]methylene]hydrazino]acetic acid

CBNumber:: CB72567410

???:: C14H12N4O6

??? ??:: 332.27

MOL ??:: 57268-33-4.mol

?? ?? 34

?????????B(50mg)(5-(4-?????)-2-??????-(2-??????)??????) ??

???: >110°C (dec.)

?? ?: 602.0±65.0 °C(Predicted)

??: 1.53±0.1 g/cm3(Predicted)

?? ??: -20°C Freezer, Under inert atmosphere

???: DMSO(?? ???), ???(?? ???)

?? ?? (pKa): 4.05±0.10(Predicted)

??? ??: ??

??? ??: ??? ??

??: ????? ?? ?????

?? ??: ???(???)

?? ? ?? ??
?? ? ???? ?? (GHS)

WGK ??	WGK 3
HS ??	2932190002
???? ???	11 - Combustible Solids

????(GHS):

?? ?:

Warning

??·?? ??:

??	??·?? ??	?? ??	??	?? ?	P- ??
H302	??? ???	?? ?? ?? - ??	?? 4	??	P264, P270, P301+P312, P330, P501
H315	??? ??? ???	????? ?? ?????	?? 2	??	P264, P280, P302+P352, P321,P332+P313, P362
H319	?? ?? ??? ???	?? ? ?? ?? ??? ??	?? 2A	??	P264, P280, P305+P351+P338,P337+P313P
H335	?? ???? ??? ? ??	?? ???? ?? - 1? ??;???? ??	?? 3	??

??????:

P280	????/???/???/?????? ?????.
P305+P351+P338	?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.

?????????B(50mg)(5-(4-?????)-2-??????-(2-??????)??????) C??? ??, ??, ??

??

5-(4-Nitrophenyl)-2-furaldehyde-(2-carboxymethyl) Semicarbazone is an impurity in the synthesis of Dantrolene (D185000), a muscle relaxant (skeletal). Dantrolene is used in the treatment of malignant hyperthermia.

?????????B(50mg)(5-(4-?????)-2-??????-(2-??????)??????) ?? ?? ? ???

???

?? ??

?????????B(50mg)(5-(4-?????)-2-??????-(2-??????)??????) ?? ??

???( 34)?? ??

???	??	???	??	?? ?	??
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?????????B(50mg)(5-(4-?????)-2-??????-(2-??????)??????) ?? ??:

DANTROLENE

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