ChemicalBook >?? ???? >?? ??>???? ?? ???>(S)-????

(S)-????

(S)-???? ??? ???

?? ??:: 70989-04-7

???:: (S)-????

???(??):: (S)-????

???:: (S)-MEPHENYTOIN

???(??):: Mephenitoin S;(S)-MEPHENYTOIN;(S)-Mephenitoin;(S)-Mephenytoine;(S)-(+)-MEPHENYTOIN;Mephenytoin Impurity 2;(S)-Mephenytoin - Bio-X ?;(S)-Mephenytoin, 10 mM in DMSO;(S)-5-ETHYL-3-METHYL-5-PHENYLHYDANTOIN;(5S)-5-Ethyl-3-methyl-5-phenylhydantoin

CBNumber:: CB7257425

???:: C12H14N2O2

??? ??:: 218.25

MOL ??:: 70989-04-7.mol

MSDS ??:: SDS

?? ?? 124

(S)-???? ??

???: 135-138 °C

??: 1.154±0.06 g/cm3(Predicted)

?? ??: 2-8°C

???: DMSO: ??? ? ??

??? ??: ??

??? ??: ??? ??

?? ?? (pKa): 8.07±0.70(Predicted)

??: ???

InChI: 1S/C12H14N2O2/c1-3-12(9-7-5-4-6-8-9)10(15)14(2)11(16)13-12/h4-8H,3H2,1-2H3,(H,13,16)/t12-/m0/s1

InChIKey: GMHKMTDVRCWUDX-LBPRGKRZSA-N

SMILES: CC[C@]1(NC(=O)N(C)C1=O)c2ccccc2

?? ? ?? ??
?? ? ???? ?? (GHS)

??? ??	Xn
?? ???? ??	22-36/37/38
?????	26-36
WGK ??	2
HS ??	29332100
???? ???	11 - Combustible Solids
Hazard Classifications	Acute Tox. 4 Oral Eye Irrit. 2 Skin Irrit. 2 STOT SE 3

????(GHS):

?? ?:

Warning

??·?? ??:

??	??·?? ??	?? ??	??	?? ?	P- ??
H302	??? ???	?? ?? ?? - ??	?? 4	??	P264, P270, P301+P312, P330, P501
H315	??? ??? ???	????? ?? ?????	?? 2	??	P264, P280, P302+P352, P321,P332+P313, P362
H319	?? ?? ??? ???	?? ? ?? ?? ??? ??	?? 2A	??	P264, P280, P305+P351+P338,P337+P313P
H335	?? ???? ??? ? ??	?? ???? ?? - 1? ??;???? ??	?? 3	??

??????:

P261	??·?·??·???·??·...·????? ??? ????.
P264	?? ??? ?? ??? ????.
P264	?? ??? ?? ??? ????.
P270	? ??? ??? ??? ???, ???? ???? ???.
P301+P312	??? ???? ??? ????(??)? ??? ????.
P302+P352	??? ??? ??? ?? ????.
P305+P351+P338	?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.

NFPA 704

	0
2		0

(S)-???? C??? ??, ??, ??

??? ??

White Crystalline Solid

??

(S)-Mephenytoin can be used as an anticonvulsant agent.

Biochem/physiol Actions

CYP2B6 & CYP2C19 substrate. Methenytoin isomer. Anticonvulsant; antiepileptic.

(S)-???? ?? ?? ? ???

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?? ??

(S)-???? ?? ??

???( 124)?? ??

???	??	???	??	?? ?	??
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(S)-???? ?? ??:

(R)-MEPHENYTOIN,(R)-(-)-MEPHENYTOIN 4-HYDROXY MEPHENYTOIN 4-HYDROXY MEPHENYTOIN-D3 (S)-MEPHENYTOIN 2-PHENYLBUTYRYLUREA 7,8-DIHYDROXY-6-METHOXYCOUMARIN 5-Phenylhydantoin (S)-(+)-2-Phenylglycine amide Mephenytoin S-(+)-N-Desmethyl Mephenytoin (S)-(+)-N-3-Benzylnirvanol rac N-Desmethyl Mephenytoin-deuterated,rac N-Desmethyl Mephenytoin-D5 (Major) RAC MEPHENYTOIN-D3 1,2-Ethanediamine,N2,N2-dimethyl-1-phenyl-,(1S)-(9CI) DESMETHYL MEPHENYTOIN,rac N-Desmethyl Mephenytoin N-DESMETHYL MEPHENYTOIN-D5 rac Mephenytoin-D5 MEPHENYTOIN USP(CRM STANDARD)

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