ChemicalBook >?? ???? >((R)-2-???-4-?-1-????)???????t-??????
((R)-2-???-4-?-1-????)???????t-??????
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((R)-2-???-4-?-1-????)???????t-?????? ??
- ?? ?
- 475.1±45.0 °C(Predicted)
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- 1.097±0.06 g/cm3(Predicted)
- ?? ??
- 2-8°C, stored under nitrogen
- ?? ?? (pKa)
- 11.17±0.46(Predicted)
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- White to yellow Solid
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((R)-2-???-4-?-1-????)???????t-?????? C??? ??, ??, ??
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tert-Butyl (R)-(1-([1,1''-Biphenyl]-4-yl)-3-oxopropan-2-yl)carbamate is an impurity of LCZ696 (L270005), a novel dual-acting inhibitor of angiotensin II receptor and neprilysin, which can be used for blood pressure reduction.((R)-2-???-4-?-1-????)???????t-?????? ?? ?? ? ???
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((R)-2-???-4-?-1-????)???????t-?????? ?? ??
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((R)-2-???-4-?-1-????)???????t-?????? ?? ??:
N-[2’-(1H-tetrazol-5-yl)biphenyl-4-yl methyl]-N-Valeryl-(L)-Valine benzyl ester
Ethyl (2R,4S)-4-([1,1'-biphenyl]-4-ylmethyl)-2-methyl-4-(2,5-dioxopyrrolidin-1-yl)butanoate
(2R,4S)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)aMino)-2-Methylpentanoate
(S)-5-[(Biphenyl-4-yl)methyl]-1-(2,2-dimethylpropionyl)pyrrolidin-2-one
(R,E)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)aMino)-2-Methylpent-2-enoic acid
2-Pyrrolidinone, 5-([1,1'-biphenyl]-4-ylMethyl)-3-Methyl-, (3R,5S)-
LCZ696 InteMediate
(2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-aMino-2-Methylpentanoic acid hydrochloride
(2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)aMino)-2-Methylpentanoic acid
sacubitril
(2R,4R)-5-(Biphenyl-4-yl)-4-[(tert-butoxycarbonyl)amino]-2-methylpentanoic acid
(2R,4S)-4-([1,1'-Biphenyl]-4-ylmethyl)-4-(4-ethoxy-4-oxobutanamido)-2-methylbutanoic acid
(2S,4R)-5-(Biphenyl-4-yl)-4-[(tert-butoxycarbonyl)amino]-2-methylpentanoic acid
AHU-377 (heMicalciuM salt)
(2R,4S)-4-([1,1'-Biphenyl]-4-ylmethyl)-2-methyl-4-(2,5-dioxopyrrolidin-1-yl)butanoic acid
(2R,4S)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-aMino-2-Methylpentanoate
Valsartan
LCZ696 interMediate