?????;???,3-(??-??????)-4-?????-,???
|
|
?????;???,3-(??-??????)-4-?????-,??? ??
- ???
- approximate 161℃
- ??
- ±0°
- ??
- 1.3128 g/cm3 (solid)
- ?? ??
- 2-8°C
- ???
- ?? ???(96%)? ?? ? ??, ???? ? ???, ??????? ?? ?? ????.
- ??? ??
- powder
- ??
- ???? ?? ??
- ??????(pH)
- pH (10g/l, 25℃) : 7.2～8.3
- Merck
- 14,10038
- BCS Class
- 1,2
- InChI
- 1S/C19H16O4.Na/c1-12(20)11-15(13-7-3-2-4-8-13)17-18(21)14-9-5-6-10-16(14)23-19(17)22;/h2-10,15,21H,11H2,1H3;/q;+1/p-1
- InChIKey
- KYITYFHKDODNCQ-UHFFFAOYSA-M
- SMILES
- [Na].CC(=O)CC(c1ccccc1)C2=C(O)c3ccccc3OC2=O
- CAS ??????
- 129-06-6(CAS DataBase Reference)
??
- ?? ? ?? ??
- ?? ? ???? ?? (GHS)
| ??? ?? | T+ | ||
|---|---|---|---|
| ?? ???? ?? | 61-28 | ||
| ????? | 53-36/37/39-45-36/37-28 | ||
| ????(UN No.) | UN 1544 6.1/PG 2 | ||
| WGK ?? | 1 | ||
| RTECS ?? | GN4725000 | ||
| TSCA | TSCA listed | ||
| ?? ?? | 6.1(a) | ||
| ???? | II | ||
| HS ?? | 29322090 | ||
| ???? ??? | 6.1A - Combustible acute toxic Cat. 1 and 2 very toxic hazardous materials |
||
| Hazard Classifications | Acute Tox. 2 Oral Aquatic Chronic 3 Repr. 1B |
||
| ?? | LD50 in male rats, female rats, mice, rabbits (mg/kg): 323, 58, 374, ~800 orally (Hagen); also reported as LD50 in male, female rats (mg/kg): 100.3, 8.7 orally (Back) |
?????;???,3-(??-??????)-4-?????-,??? C??? ??, ??, ??
??? ??
Colorless solid??
Warfarin Sodium (Crystalline Clathrate) is used for pharmaceutical care for patients with chronic heart failure and renal dysfunction.?? ??
Slightly bitter crystalline powder. An anticoagulant used as a rodenticide.?? ???
A coumarin derivative, a lactone. Lactones are similar to esters reactive chemistries.????
Warfarin sodium is highly toxic orally in humans.????
When heated to decomposition, Warfarin sodium emits toxic fumes of sodium oxide.Clinical Use
By virtue of its great potency, warfarin sodium at firstwas considered unsafe for use in humans and was used veryeffectively as a rodenticide, especially against rats. At theproper dosage level, however, it can be used in humans, especiallythrough the intravenous route.Safety Profile
Poison to humans by ingestion. Experimental poison by ingestion and intravenous routes. Human systemic effects by ingestion: dermatitis. Human reproductive effects by ingestion: fetotoxicity, abnormal condition of newborn at birth, other newborn physical effects, and teratogenic effects includmg developmental abnormalities of the eye and ear, craniofacial area, skin and appendages, musculoskeletal system, cardiovascular system, and gastrointestinal system of the fetus. ,4n experimental teratogen. Other experimental reproductive effects. Mutation data reported. An anticoagulant drug. When heated to decomposition it emits toxic fumes of Na2O.?????;???,3-(??-??????)-4-?????-,??? ?? ?? ? ???
???
?? ??
?????;???,3-(??-??????)-4-?????-,??? ?? ??
???( 449)?? ??
| ??? | ?? | ??? | ?? | ?? ? | ?? |
|---|---|---|---|---|---|
| Hebei Yanxi Chemical Co., Ltd. | +86-17531190177 |
faithe@yan-xi.com | China | 5853 | 58 |
| Wuhan Fortuna Chemical Co., Ltd | +86-27-59207850 |
info@fortunachem.com | China | 6001 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +86-17732866630 |
mina@chuanghaibio.com | China | 18126 | 58 |
| Henan Bao Enluo International TradeCo.，LTD | +86-17331933971 |
deasea125996@gmail.com | China | 2472 | 58 |
| airuikechemical co., ltd. | +86-18353166132 |
sales02@airuikechemical.com | China | 983 | 58 |
| Hebei Yiduo Import and Export Co., Ltd. | |
joycedemei1505@outlook.com | China | 215 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21585 | 55 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 33024 | 60 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418679 +86-18949832763 |
info@tnjchem.com | China | 2988 | 55 |
| career henan chemical co | +86-0371-86658258 |
sales@coreychem.com | China | 29812 | 58 |