ChemicalBook >?? ???? >????A4
????A4
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????A4 ??
- ???
- 212-215°
- ??
- D20 +106° (c = 0.25 in acetone)
- ?? ?
- 732.9±60.0 °C(Predicted)
- ??
- 1.20±0.1 g/cm3(Predicted)
- ?? ??
- 0-6°C
- ???
- DMF: soluble; DMSO: soluble; Ethanol: soluble; Methanol: soluble
- ??? ??
- ??
- ?? ?? (pKa)
- 12.46±0.70(Predicted)
- ??
- White to off-white
- Henry's Law Constant
- 7.7×106 mol/(m3Pa) at 25℃, Ebert et al. (2023)
- InChIKey
- VOZIAWLUULBIPN-PNCZYSMLNA-N
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- ?? ? ???? ?? (GHS)
| ????(UN No.) | 2588 | ||
|---|---|---|---|
| ?? ?? | 6.1(b) | ||
| ???? | III |
| ????(GHS): |
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| ?? ?: | Danger | ||||||||||||||
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????A4 C??? ??, ??, ??
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Milbemycin A4 is the prominent member of a complex family of macrocyclic lactones that contain a characteristic spiroketal group produced from the fermentation of soil bacterium S. hygroscopicus subsp. aureolacrimosus. As a compound that potentiates glutamate and GABA-gated chloride-channel opening, milbemycin 4 is used as a nematocide and insecticide.??
Milbemycins are a complex family of macrocyclic lactones containing a highly characteristic spiroketal group, produced by Streptomyces hydroscopicus subsp. aureolarcrimosus. Milbemycin A4 is the dominant member of a group of analogues containing a 25-ethyl substituent. Milbemycin A4 is a highly selective and potent nematocide and insecticide. Like the closely related avermectins, milbemycins are thought to act on chloride-gated ion channels.????A4 ?? ?? ? ???
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????A4 ?? ??
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| ??? | ?? | ??? | ?? | ?? ? | ?? |
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????A4 ?? ??:
MilbeMycin A3 OxiMe
MilbeMycin A4 OxiMe
Miconazole IMpurity I
Miconazole IMpurity B
MILRINONE RELATED COMPOUND A (50 MG) (1,6-DIHYDRO-2-METHYL-6-OXO(3,4'-BIPYRIDINE)-5-CAR-BOXAMIDE)
2-methyl-6-oxo-1,6-dihydro-[3,4'-bipyridine]-5-carboxylic acid
1,6-Dihydro-2-(hydroxyMethyl)-6-oxo-[3,4'-bipyridine]-5-carbonitrile
Milbemycin oxime
Isoconazole
Milbemycin EP Impurity D
Milrinone Impurity 13
Miconazole Impurity
5-Decyano 5-(Ethyl Formate) Milrinone
Milrinone Impurity 17
Milrinone Impurity 14
Milbemycin EP Impurity E
Miconazole EP Impurity E
MILBEMECTIN A3