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11-????????????

11-????????????
11-???????????? ??? ???
?? ??:
72-23-1
???:
11-????????????
???(??):
11-????????????
???:
11-DEHYDROCORTICOSTERONE
???(??):
Pregn-4-ene-3,11,20-trione, 21-hydroxy-;NSC-9702;11-Oxocorticosterone;KENDALL'S COMPOUND A;Kendall’S Compound ‘A’;11-Dehydrocorticosteron;11-DEHYDROCORTICOSTERONE;KENDALL'S COMPOUND ''A'';4-PREGNEN-21-OL-3,11,20-TRIONE;4-Pregene-21-ol-3,11,20-trione
CBNumber:
CB7425329
???:
C21H28O4
??? ??:
344.44
MOL ??:
72-23-1.mol

11-???????????? ??

???
183.5°C
?? ?
399.53°C (rough estimate)
??
1.0556 (rough estimate)
???
1.4430 (estimate)
?? ??
Refrigerator
???
?????(?? ???), ???(?? ???), ???(?? ???)
??? ??
??
??? ??
??? ??
?? ?? (pKa)
12.95±0.10(Predicted)
??
???? ?? ???
??? (Optical Rotation)
+34725 (c 0.23, C6H6)

??

11-???????????? C??? ??, ??, ??

??

11-Dehydrocorticosterone is a precursor to corticosterone (C695700), converted by 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) which plays a role in glucocorticoid-induced insulin resistance.

??

ChEBI: An 11-oxo steroid that is corticosterone in which the hydroxy substituent at the 11beta position has been oxidised to give the corresponding ketone.

11-???????????? ?? ?? ? ???

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11-???????????? ?? ??

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