PROXYPHYLLINE
PROXYPHYLLINE ??
- ???
- 134-136°C
- ?? ?
- 487.2±51.0 °C(Predicted)
- ??
- 1.46±0.1 g/cm3(Predicted)
- ?? ??
- Inert atmosphere,Room Temperature
- ???
- DMF: 10 mg/ml
DMSO: 10 mg/ml
Ethanol: 1 mg/mlPBS (pH 7.2): 1 mg/ml
- ??? ??
- Solid
- ?? ?? (pKa)
- 14.55±0.20(Predicted)
- ??
- ???? ?????
- ???
- 285.7g/L(?? ???)
- Merck
- 14,7905
- InChI
- InChI=1S/C10H14N4O3/c1-6(15)4-14-5-11-8-7(14)9(16)13(3)10(17)12(8)2/h5-6,15H,4H2,1-3H3
- InChIKey
- KYHQZNGJUGFTGR-UHFFFAOYSA-N
- SMILES
- N1(CC(O)C)C2=C(N(C)C(=O)N(C)C2=O)N=C1
- CAS ??????
- 603-00-9(CAS DataBase Reference)
- NIST
- Proxyphylline(603-00-9)
??
- ?? ? ?? ??
- ?? ? ???? ?? (GHS)
| ??? ?? |
Xn |
|
|
| ?? ???? ?? |
22 |
|
|
| ????? |
36 |
|
|
| WGK ?? |
3 |
|
|
| RTECS ?? |
XH5907500 |
|
|
| HS ?? |
2939.59.0000 |
|
|
| ????(GHS): |
|
| ?? ?: |
Warning |
| ??·?? ??: |
| ?? |
??·?? ?? |
?? ?? |
?? |
?? ? |
?? ?? |
P- ?? |
| H302 |
??? ??? |
?? ?? ?? - ?? |
?? 4 |
?? |
|
P264, P270, P301+P312, P330, P501 |
|
| ??????: |
|
| NFPA 704 |
|
|
|
PROXYPHYLLINE C??? ??, ??, ??
??? ??
White Solid
??
A metabolite of Theophylline in human plasma.
Purification Methods
Crystallise it from EtOH, aqueous MeOH or EtOAc. Roth Archiv Pharmazie 292 234 1959, Zelnik et al. Bull Soc Chim Fr 1733 1956, Beilstein 26 III/IV 2366.]
PROXYPHYLLINE ?? ?? ? ???
???
?? ??
PROXYPHYLLINE ?? ??
???( 220)?? ??
PROXYPHYLLINE ?? ??:
???? ?????
diniprofylline
Tazifylline
Xanthinol nicotinate
PROXYPHYLLINE
Xanthinol
1,3-DIMETHYL-7-(OXIRAN-2-YLMETHYL)-2,3,6,7-TETRAHYDRO-1H-PURINE-2,6-DIONE
(S)-Proxyphylline
(R)-Proxyphylline
Xantifibrate
8-CHLORO-7-(3-CHLORO-2-HYDROXYPROPYL)-1,3-DIMETHYL-2,3,6,7-TETRAHYDRO-1H-PURINE-2,6-DIONE
7-(3-CHLORO-2-HYDROXYPROPYL)-1,3-DIMETHYL-2,3,6,7-TETRAHYDRO-1H-PURINE-2,6-DIONE
8-BROMO-7-(3-CHLORO-2-HYDROXYPROPYL)-1,3-DIMETHYL-2,3,6,7-TETRAHYDRO-1H-PURINE-2,6-DIONE
1,3-DIMETHYL-8-MORPHOLINO-7-(2-OXIRANYLMETHYL)-2,3,6,7-TETRAHYDRO-1H-2,6-PURINEDIONE
8-BROMO-7-(2-HYDROXYBUTYL)-1,3-DIMETHYL-2,3,6,7-TETRAHYDRO-1H-PURINE-2,6-DIONE
8-BROMO-7-(2-HYDROXYPROPYL)-1,3-DIMETHYL-2,3,6,7-TETRAHYDRO-1H-PURINE-2,6-DIONE
8-(BENZYLAMINO)-7-(3-CHLORO-2-HYDROXYPROPYL)-1,3-DIMETHYL-2,3,6,7-TETRAHYDRO-1H-2,6-PURINEDIONE
