AUTOCAMTIDE-2-???????
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AUTOCAMTIDE-2-??????? ??
- ?? ??
- -20°C
- ???
- H2O: ???
- ??? ??
- ????? ??
- ??
- ???
- ???? ??
- synthetic
- ???
- Soluble to 1 mg/ml in water
- InChIKey
- COEHZSYVSXUBHI-CYZNULJVSA-N
??
| ??? ?? | Xn,F | ||
|---|---|---|---|
| ?? ???? ?? | 20/21/22-36-11 | ||
| ????? | 22-24/25-26-36/37-16 | ||
| WGK ?? | 3 | ||
| ???? ??? | 11 - Combustible Solids |
AUTOCAMTIDE-2-??????? C??? ??, ??, ??
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Autocamtide 2-related inhibitory peptide has been used:- To inhibit calmodulin kinase II (CaMKII) action in virulent Theileria infected macrophages
- To study its influence on oxidative stress associated with neural cell death after hypoxia-ischemia, using neonatal hippocampal slice cultures
- To quench the phosphorylation of recombinant synGA (GTPase-activating protein) induced by CaMKII
Biochem/physiol Actions
Calmodulin kinase II facilitates the calcium-dependent L-type calcium channels. Autocamtide 2-related inhibitory peptide action does not influence cAMP (cyclic adenosine monophosphate)-dependent protein kinase II, calmodulin-dependent protein kinase IV and protein kinase C. Increased expression of calmodulin kinase II is observed in structural heart disease, indicated by myocardial infarction. Thus, inhibition of calmodulin kinase II activity might serve as a protective effect against structural heart disease, as it is found to prevent cardiac hypertrophy, dilation and dysfunction.AUTOCAMTIDE-2-??????? ?? ?? ? ???
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AUTOCAMTIDE-2-??????? ?? ??
???( 146)?? ??
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AUTOCAMTIDE-2-??????? ?? ??:
H-GLY-GLY-SER-LEU-TYR-SER-PHE-GLY-LEU-NH2
ALLATOSTATIN IV
RGDV
Z-Ile-Glu-Pro-Phe-OMe
ATRIAL NATRIURETIC FACTOR (1-28) (RAT)
H-GLY-ASP-GLY-ARG-LEU-TYR-ALA-PHE-GLY-LEU-NH2
ALLATOSTATIN I
H-LEU-SER-LYS-LEU-NH2
RIP
KN-93 Phosphate
AUTOCAMTIDE-2 RELATED INHIBITORY PEPTIDE II, CELL-PERMEABLE
AUTOCAMTIDE-2 RELATED INHIBITORY PEPTIDE, MYRISTOYLATED
AUTOCAMTIDE-2 RELATED INHIBITORY PEPTIDE II
[LYS3, PHE10, TYR13]-AUTOCAMTIDE-2-RELATED INHIBITORY PEPTIDE (AIP) ANALOG,[LYS3,PHE10,TYR13]-AUTOCAMTIDE-2-RELATED INHIBITORY PEPTIDE
AUTOCAMTIDE-2-RELATED INHIBITORY PEPTIDE
H-VAL-PRO-PRO-OH
PEP2M
Histatin 5