ChemicalBook >?? ???? >???>??? ??>???>BQ-788

BQ-788

BQ-788 ??? ???

?? ??:: 156161-89-6

???:: BQ-788

???(??):: CS-1494;BQ-788 SODIUM;BQ789 Sodium Salt;1-ELAIDYLPHOSPHOCHOLINE, >97%;BQ788 SODIUM SALT; BQ 788 SODIUM SALT;BQ 788 sodium salt, ETB receptor antagonist;BQ-788 SYNTHETIC >97% ETB ENDOTHELIN REC EPT;N-[N-[N-[(2,6-Dimethyl-1-piperidinyl)carbonyl]-;N-cis-2,6-dimethylpiperidinocarbonyl-L-γMeLeu-D-Trp(COOMe)-D-Nle-ONa;2,6-Dimethylpiperidinecarbonyl-γ-Methyl-Leu-Nin-(Methoxycarbonyl)-D-Trp-D-Nle

CBNumber:: CB7710904

???:: C34H52N5NaO7

??? ??:: 665.81

MOL ??:: 156161-89-6.mol

MSDS ??:: SDS

?? ?? 84

BQ-788 ??

?? ??: -20°C

???: ??????: 0.3 mg/mL ? ???

??? ??: ??

??? ??: ??? ??

??: ???

???: acetonitrile: 0.3mg/mL
DMSO: 1.2mg/mL
ethanol: 1.2mg/mL
H2O: slightly soluble

InChIKey: IBWYJVKAVOHKHB-IAZAOAQXNA-N

SMILES: C(C1=CN(C(=O)OC)C2=CC=CC=C12)[C@H](C(=O)N[C@@H](C(=O)O)CCCC)NC(=O)[C@H](CC(C)(C)C)NC(N1[C@@H](CCC[C@@H]1C)C)=O.[NaH] |&1:14,18,29,38,42,r|

?? ? ?? ??
?? ? ???? ?? (GHS)

WGK ??	3
???? ???	11 - Combustible Solids

????(GHS):

?? ?:

Warning

??·?? ??:

??	??·?? ??	?? ??	??	?? ?	P- ??
H302	??? ???	?? ?? ?? - ??	?? 4	??	P264, P270, P301+P312, P330, P501
H315	??? ??? ???	????? ?? ?????	?? 2	??	P264, P280, P302+P352, P321,P332+P313, P362
H319	?? ?? ??? ???	?? ? ?? ?? ??? ??	?? 2A	??	P264, P280, P305+P351+P338,P337+P313P
H335	?? ???? ??? ? ??	?? ???? ?? - 1? ??;???? ??	?? 3	??

??????:

P261	??·?·??·???·??·...·????? ??? ????.
P280	????/???/???/?????? ?????.
P301+P312	??? ???? ??? ????(??)? ??? ????.
P302+P352	??? ??? ??? ?? ????.
P305+P351+P338	?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.

BQ-788 C??? ??, ??, ??

??

BQ-788 has been used as a selective endothelin-B (ETRB) blocker in human airway smooth muscle cells (HASMCs), uterine mesothelial cells (UtMCs)-derived vascular smooth muscle cells (VSMCs), and human umbilical vein endothelial cells (HUVECs)

???? ??

Potent, selective ET B receptor antagonist (IC 50 = 1.2 nM for inhibition of ET-1 binding to human Girardi heart cells).

Biochem/physiol Actions

Selective ETB endothelin receptor antagonist.

BQ-788 ?? ?? ? ???

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BQ-788 ?? ??

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???	??	???	??	?? ?	??
TargetMol Chemicals Inc.	+1-781-999-5354; +1-00000000000	marketing@targetmol.com	United States	32431	58
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Aladdin Scientific		tp@aladdinsci.com	United States	52906	58
TargetMol Chemicals Inc.	13564774135	marketing@targetmol.com	United States	19950	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131885	58
Shanghai Sinch Parmaceuticals Tech. Co. Ltd.	+86-21-54098501	sales@sinch.com.cn	China	11592	64

BQ-788 ?? ??:

Sodium salt EPT AC-D-NLE-OH N-ACETYL-D-ALA-D-ALA METHYL PYRROLE-1-CARBOXYLATE BQ-788

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