ChemicalBook >?? ???? >????B(1)

????B(1)

????B(1) ??? ???

?? ??:: 4135-11-9

???:: ????B(1)

???(??):: ????B(1)

???:: polymyxin B(1)

???(??):: polymyxin B(1);Polymyxin B1-[13C6,15N] TFA salt;Glucosamine Hydrochloride Impurity 33;polymyxin B1Q: What is polymyxin B1 Q: What is the CAS Number of polymyxin B1;(-)-N2-[[(6S)-6-Methyloctanoyl]-L-A2bu-L-Thr-L-A2bu-]cyclo(L-A2bu*-L-A2bu-D-Phe-L-Leu-L-A2bu-L-A2bu-L-Thr-);(S)-N-((S)-4-amino-1-(((2S,3R)-1-(((S)-4-amino-1-oxo-1-(((3S,6S,9S,12S,15R,18S,21S)-6,9,18-tris(2-aminoethyl)-15-benzyl-3-((R)-1-hydroxyethyl)-12-isobutyl-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptaazacyclotricosan-21-yl)amino)butan-2-yl)amino)-3-hydroxy-1-oxobutan-2-yl)amino)-1-oxobutan-2-yl)-6-methyloctanamide;(6S)-N-[(2S)-4-amino-1-[[(2S,3R)-1-[[(2S)-4-amino-1-oxo-1-[[(3S,6S,9S,12S,15R,18S,21S)-6,9,18-tris(2-aminoethyl)-15-benzyl-3-[(1R)-1-hydroxyethyl]-12-(2-methylpropyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptazacyclotricos-21-yl]amino]butan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-1-oxobutan-2-yl]-6-methyloctanamide

CBNumber:: CB81388907

???:: C56H98N16O13

??? ??:: 1203.48

MOL ??:: 4135-11-9.mol

?? ?? 70

????B(1) ??

?? ?: 838.79°C (rough estimate)

??: 1.0500 (rough estimate)

???: 1.6200 (estimate)

?? ??: Store at -20°C

???: PBS (pH 7.2): 2 mg/ml

??? ??: ??? ??

?? ?? (pKa): 13.08±0.70(Predicted)

??: White to off-white

???: {Dab(6-methyl-1-oxooctyl)}-Thr-{Dab}-{Dab}-{Dab}-{d-Phe}-Leu-{Dab}-{Dab}-Thr (Lactam bridge: Dab4-Thr10)

InChIKey: WQVJHHACXVLGBL-CTMZAJDNSA-N

?? ? ?? ??
?? ? ???? ?? (GHS)

????(GHS):

?? ?:

Warning

??·?? ??:

??	??·?? ??	?? ??	??	?? ?	P- ??
H302	??? ???	?? ?? ?? - ??	?? 4	??	P264, P270, P301+P312, P330, P501
H315	??? ??? ???	????? ?? ?????	?? 2	??	P264, P280, P302+P352, P321,P332+P313, P362
H319	?? ?? ??? ???	?? ? ?? ?? ??? ??	?? 2A	??	P264, P280, P305+P351+P338,P337+P313P
H335	?? ???? ??? ? ??	?? ???? ?? - 1? ??;???? ??	?? 3	??

??????:

P261	??·?·??·???·??·...·????? ??? ????.
P264	?? ??? ?? ??? ????.
P264	?? ??? ?? ??? ????.
P270	? ??? ??? ??? ???, ???? ???? ???.
P271	?? ?? ??? ? ?? ???? ?????.
P280	????/???/???/?????? ?????.
P301+P312	??? ???? ??? ????(??)? ??? ????.
P302+P352	??? ??? ??? ?? ????.
P304+P340	???? ??? ??? ?? ??? ??? ???? ?? ??? ??? ????.
P305+P351+P338	?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.
P321	(…) ??? ???.
P330	?? ?????.
P332+P313	?? ??? ??? ???? ??· ??? ????.
P337+P313	?? ?? ??? ???? ???? ??· ??? ????.
P403+P233	??? ??? ? ?? ?? ??? ???? ?????.
P405	???? ?????.
P501	...? ??? / ??? ?? ???.

NFPA 704

	0
2		0

????B(1) C??? ??, ??, ??

??

An antibacterial compound. It has a high volume of distribution and longer elimination half-life in patient with multidrug-resistant gram-negative bacterial infection.

??

ChEBI: A polymyxin having a (6R)-6-methyloctanoyl group at the amino terminus.

????B(1) ?? ?? ? ???

???

?? ??

????B(1) ?? ??

???( 70)?? ??

???	??	???	??	?? ?	??
Guangzhou PI PI BIOTECH INC	020-81716320 13602409664	Sales@pipitech.com	China	973	55
Shaanxi Dideu Medichem Co. Ltd	+86-29-81139210 17389186172	1077@dideu.com	China	3999	58
TargetMol Chemicals Inc.	+1-781-999-5354; +1-00000000000	marketing@targetmol.com	United States	32431	58
BOC Sciences	16314854226; +8616314854226	inquiry@bocsci.com	United States	19852	58
TargetMol Chemicals Inc.	+1-781-999-5354;	support@targetmol.com	United States	38999	58
Aladdin Scientific		tp@aladdinsci.com	United States	57473	58
Shanghai Scibiotron Pharmaceutical Co., Ltd	+86-16621589600	contact@scibiotron.com	China	5783	58
QUALITY CONTROL SOLUTIONS LTD.	+86-0755-66853366 +8613670046396	export03@qcsrm.com	China	24318	58
Heyuan broad spectrum Biotechnology Co., Ltd	0762-3393039 18023108599	2853058244@qq.com	China	990	58
SHANG HAI WEI LING BIOTECHNOLOGY CO.,LTD	021-13917490980 13917490980	81939905@qq.com	China	483	58

????B(1) ?? ??:

Butyl stearate Bromothymol Blue CPNQ Vitamin B series Polymyxin B1 Isoleucine sulfate Hirsutide

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