(2S,αR)-α-(Aminomethyl)-6-fluoro-3,4-dihydro-2H-1-benzopyran-2-methanol
(2S,αR)-α-(Aminomethyl)-6-fluoro-3,4-dihydro-2H-1-benzopyran-2-methanol ??? ???
?? ??:
303176-42-3
???:
(2S,αR)-α-(Aminomethyl)-6-fluoro-3,4-dihydro-2H-1-benzopyran-2-methanol
???(??):
(2S,αR)-α-(AMinoMethyl)-6-fluoro-chroMan-2-Methanol;(2S,αR)-α-(Aminomethyl)-6-fluoro-3,4-dihydro-2H-1-benzopyran-2-methanol;"(2S,aR)-a-(Aminomethyl)-6-fluoro-3,4-dihydro-2H-1-benzopyran-2-methanol";2H-1-Benzopyran-2-methanol, α-(aminomethyl)-6-fluoro-3,4-dihydro-, (αR,2S)-;(2S,αR)-α-(Aminomethyl)-6-fluoro-3,4-dihydro-2H-1-benzopyran-2-methanol, CAS 303176-42-3
CBNumber:
CB82507929
???:
C11H14FNO2
??? ??:
211.23
MOL ??:
303176-42-3.mol
(2S,αR)-α-(Aminomethyl)-6-fluoro-3,4-dihydro-2H-1-benzopyran-2-methanol ??
???
109-112°C
?? ?
383.5±37.0 °C(Predicted)
??
1+-.0.06 g/cm3(Predicted)
?? ??
Hygroscopic, Refrigerator, Under Inert Atmosphere
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?? ?? (pKa)
12.68±0.35(Predicted)
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?? ? ???? ?? (GHS)
????(GHS):
?? ?:
Warning
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P- ??
H302 ??? ???
?? ?? ?? - ??
?? 4
??
P264, P270, P301+P312, P330, P501
H315 ??? ??? ???
????? ?? ?????
?? 2
??
P264, P280, P302+P352, P321,P332+P313, P362
H319 ?? ?? ??? ???
?? ? ?? ?? ??? ??
?? 2A
??
P264, P280, P305+P351+P338,P337+P313P
H335 ?? ???? ??? ? ??
?? ???? ?? - 1? ??;???? ??
?? 3
??
??????:
P280 ????/???/???/?????? ?????.
P305+P351+P338 ?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.
(2S,αR)-α-(Aminomethyl)-6-fluoro-3,4-dihydro-2H-1-benzopyran-2-methanol C??? ??, ??, ??
??? ??
Off-White Solid
??
(+)-Nebivolol intermediate.
(2S,αR)-α-(Aminomethyl)-6-fluoro-3,4-dihydro-2H-1-benzopyran-2-methanol ?? ?? ? ???
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?? ??
(2S,αR)-α-(Aminomethyl)-6-fluoro-3,4-dihydro-2H-1-benzopyran-2-methanol ?? ??
???( 12)?? ??
Canada 1
China 9
India 2
Global 12
