ChemicalBook >?? ???? >N-((R)-1-(????-1-?)??)-3-(3-(????????)??)??????
N-((R)-1-(????-1-?)??)-3-(3-(????????)??)??????
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N-((R)-1-(????-1-?)??)-3-(3-(????????)??)?????? ??
- ???
- 90-92℃ (cyclohexane )
- ?? ?
- 530.5±50.0 °C(Predicted)
- ??
- 1.210±0.06 g/cm3(Predicted)
- ?? ??
- Sealed in dry,Room Temperature
- ???
- ?????(?? ???), ???(?? ???)
- ??? ??
- ??
- ??? ??
- ??? ??
- ?? ?? (pKa)
- 15.18±0.46(Predicted)
- ??
- ????? ?? ????
- ???
- ???
- InChI
- InChI=1S/C22H20F3NO/c1-15(19-11-5-8-17-7-2-3-10-20(17)19)26-21(27)13-12-16-6-4-9-18(14-16)22(23,24)25/h2-11,14-15H,12-13H2,1H3,(H,26,27)/t15-/m1/s1
- InChIKey
- GDEHAOJGPHEOSO-OAHLLOKOSA-N
- SMILES
- C1(CCC(N[C@@H](C2=C3C(C=CC=C3)=CC=C2)C)=O)=CC=CC(C(F)(F)F)=C1
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N-((R)-1-(????-1-?)??)-3-(3-(????????)??)?????? C??? ??, ??, ??
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N-((R)-1-(naphthalen-1-yl)ethyl)-3-(3-(trifluoroMethyl)phenyl)propanaMide is a pharmaceutical intermediate ingredient used in the preparation of cinacalcet and its salts. Cinacalcet is used for the management and treatment of secondary hyperparathyroidism (in the dialysis population), primary hyperparathyroidism (where the patient may not be a candidate for surgical treatment), and for the treatment of end-stage renal disease or the prevention of calcification in dialysis patients.N-((R)-1-(????-1-?)??)-3-(3-(????????)??)?????? ?? ?? ? ???
???
3-(3-Trifluoromethylphenyl)propionic acid
3-(3-(????????)??)??????????
2-PropenaMide, N-[(1R)-1-(1-naphthalenyl)ethyl]-3-[3-(trifluoroMethyl)phenyl]-, (2E)-
2-Propynamide, N-[(1R)-1-(1-naphthalenyl)ethyl]-3-[3-(trifluoromethyl)phenyl]-
??3-(3-(????????)??)???????
????
???
(+/-)1-(1-Naphthyl)ethylamine
(R)-(+)-1-(1-Naphthyl)ethylamine hydrochloride
(R)-(+)-1-(1-Naphthyl)ethylamine
?? ??
N-((R)-1-(????-1-?)??)-3-(3-(????????)??)?????? ?? ??
???( 112)?? ??
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N-((R)-1-(????-1-?)??)-3-(3-(????????)??)?????? ?? ??:
(αR)-α-Methyl-N-[3-[3-(trifluoroMethyl)phenyl)propyl]-1-napthaleneMethanaMine-N-oxide
(R)-1-(5,6-dihydronaphthalen-1-yl)ethan-1-amine
3-(3-Trifluoromethylphenyl)propionic acid
Cinacalcet hydrochloride
1'-Acetonaphthone
Methanesulfonic acid 3-(3-trifluoroMethylphenyl)propyl ester
3-(3-METHYLPHENYL)PROPIONIC ACID
N-(1-(5,6,7,8-tetrahydronaphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)propanamide
3-[o-(alpha,alpha,alpha-trifluorotolyl)]propionic acid
1-NaphthaleneMethanaMine, 5,6,7,8-tetrahydro-α-Methyl-, (αR)-
1-NaphthaleneMethanaMine, α-Methyl-N-[[3-(trifluoroMethyl)phenyl]Methyl]-, (αR)-
(R)-1-(Naphthalen-2-yl)ethanamine hydrochloride
(R)-N-(1-(naphthalen-1-yl)ethyl)-3-(M-tolyl)propan-1-aMine
Cinacalcet 7,8-Dihydro Racemate HCl
Cinacalcet Impurity B
4-(TRIFLUOROMETHYL)HYDROCINNAMIC ACID
Cinacalcet Impurity D
3-(3'-TRIFLUOROMETHYL PHENYL) PROPANOL