ChemicalBook >?? ???? >5-(2-??????)-1H-??-3-??????
5-(2-??????)-1H-??-3-??????
|
|
5-(2-??????)-1H-??-3-?????? ??
- ?? ?
- 364.7±32.0 °C(Predicted)
- ??
- 1.28±0.1 g/cm3(Predicted)
- ?? ??
- Sealed in dry,Room Temperature
- ?? ?? (pKa)
- 13.87±0.50(Predicted)
- ??? ??
- Solid
- ??
- Light yellow to brown Solid
- Dielectric constant
- 5.5（22.0℃）
- InChI
- InChI=1S/C11H7FN2/c12-10-4-2-1-3-9(10)11-5-8(6-13)7-14-11/h1-5,7,14H
- InChIKey
- ZDEFHFJZEDEKJO-UHFFFAOYSA-N
- SMILES
- N1C(C2=CC=CC=C2F)=CC(C#N)=C1
??
- ?? ? ?? ??
- ?? ? ???? ?? (GHS)
| HS ?? | 2933998090 |
|---|
| ????(GHS): |
|
||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ?? ?: | Warning | ||||||||||||||
| ??·?? ??: |
|
||||||||||||||
| ??????: |
|
5-(2-??????)-1H-??-3-?????? C??? ??, ??, ??
??
5-(2-fluorophenyl)-1H-pyrrole-3-carbonitrile is an important pharmaceutical intermediate component for the preparation of vonorasan fumarate, vonoprazan key intermediate, and vorexanol fumarate intermediate.??
5-(2-Fluorophenyl)-1H-pyrrole-3-carbonitrile is an impurity of Vonoprazan (V767010) a novel potassium-competitive acid blocker for the treatment of acid-related diseases.?? ??
5-(2-Fluorophenyl)-1H-pyrrole-3-carbonitrile is a crucial pharmaceutical intermediate primarily used as the key raw material for synthesizing Vonoprazan Fumarate (a novel potassium-competitive acid blocker for treating gastric ulcers, duodenal ulcers, reflux esophagitis, etc.).It can also serve as a building block for the development of pyrrole-containing drug compounds, and as a reference standard for impurity analysis and reaction monitoring in drug synthesis.5-(2-??????)-1H-??-3-?????? ?? ?? ? ???
???
2'-Fluoroacetophenone
2-chloro-5-(2-fluorophenyl)-1H-pyrrole-3-carbonitrile
2-[2-(2-??????)-2-????]???????
Benzenecarbothioic acid, S-[3-cyano-5-(2-fluorophenyl)-1H-pyrrol-2-yl] ester
2-???-2'-?????????
Benzenebutanenitrile, 2-fluoro-α-(iminomethyl)-γ-oxo-
1H-Pyrrole-3-carbonitrile, 2,2'-dithiobis[5-(2-fluorophenyl)-
N,N-?????????
????
?? ??
5-(2-??????)-1H-??-3-?????? ?? ??
???( 281)?? ??
| ??? | ?? | ??? | ?? | ?? ? | ?? |
|---|---|---|---|---|---|
| TAIZHOU YUXIN BIOTECHNOLOGY CO,.LTD | +86-576-88902229;+86-0576-88902229 +8613968687450 |
yuxin@yuxchem.com | China | 167 | 58 |
| JUYE XIANDAI fine chemistry Co.,Ltd | +86-18958038633; +8618958038633 |
tony@sdhypharma.com | China | 64 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615350571055 |
Sibel@chuanghaibio.com | China | 8738 | 58 |
| Hebei Yanxi Chemical Co., Ltd. | +8618531123677 |
faithe@yan-xi.com | China | 5853 | 58 |
| Wuhan Fortuna Chemical Co., Ltd | +86-27-59207850 |
info@fortunachem.com | China | 5990 | 58 |
| Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +8615965530500 |
nickzhang@hangyubiotech.com | China | 9945 | 58 |
| Shandong Huisheng Import & Export Co., Ltd. | +86-13176845580 |
da@zhongda-biotech.com | China | 232 | 58 |
| Anhui Zhongda Biotechnology Co., Ltd | +8619956560829 |
justine@zhongda-biotech.com | China | 286 | 58 |
| Anhui Zhongda Biotechnology Co., Ltd | +8615689548120 |
linda@zhongda-biotech.com | China | 193 | 58 |
| Hebei Xinsheng New Material Technology Co., LTD. | +86-16632316109 |
xinshengkeji@xsmaterial.com | China | 1085 | 58 |
5-(2-??????)-1H-??-3-?????? ?? ??:
2-chloro-5-(2-fluorophenyl)-1H-pyrrole-3-carbonitrile
3-Pyridinesulfonic acid
2-[2-(2-Fluorophenyl)-2-oxoethyl]propanedinitrile
5-(2-Fluorophenyl)-1H-pyrrole-3-carbaldehyde
3-N,N-dimethylsulfamoylpyridine
(5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl) methanol
1H-Pyrrole-3-carboxylic acid, 5-(2-fluorophenyl)-, ethyl ester
5-(4-fluorophenyl)-1H-pyrrole-3-carbonitrile
1H-PYRROLE-3-METHANOL, 5-(2-FLUOROPHENYL)-
PYRIDINE-2-SULFONIC ACID
1-(5-(2-fluorophenyl)-1-(pyridin-2-ylsulfonyl)-1H-pyrrol-3-yl)-N- methylmethanamine fumarate
(Z)-N-((5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)methylene)methanamine oxide
1-methylpyridin-1-ium-4-sulfonate
4-Pyridinesulphonic acid
pyridine-3-sulfonyl chloride
1H-Pyrrole-3-carbonitrile,5-(2-fluorophenyl)-1-(3-pyridinylsulfonyl)-
5-(2-Fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrole-3-carbaldehyde
5-chloropyridine-3-sulfonyl chloride