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NCX 116

NCX 116 ??? ???
?? ??:
860005-21-6
???:
NCX 116
???(??):
Latanoprostene bunod;Latanoprost nitrate;NCX 116;PF-3187207;Latanoprostene API;Latanoprostene (PF-3187207);Latanoprostene bunod, 10 mM in DMSO;Inhibitor,Latanoprostene bunod,NCX 116,inhibit,NCX-116;(Z)-4-(nitrooxy)butyl 7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((R)-3-hydroxy-5-phenylpentyl)cyclopentyl)hept-5-enoate;4-(nitrooxy)butyl (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2- ((R)-3-hydroxy-5-phenylpentyl)cyclopentyl)hept-5- enoate
CBNumber:
CB83070709
???:
C27H41NO8
??? ??:
507.62
MOL ??:
860005-21-6.mol

NCX 116 ??

?? ?
658.3±55.0 °C(Predicted)
??
1.178±0.06 g/cm3(Predicted)
?? ??
Hygroscopic, -86°C Freezer, Under inert atmosphere
???
?????(?? ???), ???(?? ???)
?? ?? (pKa)
14.84±0.70(Predicted)
??? ??
??
??
??~???
???
???, ??? ???
InChIKey
LOVMMUBRQUFEAH-UIEAZXIASA-N
SMILES
C(OCCCCO[N+]([O-])=O)(=O)CCC/C=C\C[C@H]1[C@@H](O)C[C@@H](O)[C@@H]1CC[C@@H](O)CCC1=CC=CC=C1
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
????(GHS): Health Hazard (GHS08)
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H361 ?? ?? ????? ??? ??? ??? ??? ???? ?? ?? 2 ?? P201, P202, P281, P308+P313, P405,P501
??????:
P201 ?? ? ?? ???? ?????.
P202 ?? ?? ?? ??? ?? ???? ??? ???? ???.
P281 ???? ?? ???? ?????
P308+P313 ?? ?? ??? ???? ???? ??· ??? ????.
P405 ???? ?????.
P501 ...? ??? / ??? ?? ???.

NCX 116 C??? ??, ??, ??

??

Latanoprostene Bunod is a derivative of Latanoprost and is used in the treatment of interocular pressure.

NCX 116 ?? ?? ? ???

???

?? ??


NCX 116 ?? ??

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NCX 116 ?? ??:

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