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Hoechst 33258

Hoechst 33258 ??? ???
?? ??:
23491-45-4
???:
Hoechst 33258
???(??):
BBIH;BXI-72;H33258;abs9129;Ht-33258;hoe33058;NSC334072;HOE 33258;nsc-322921;33258hoechst
CBNumber:
CB8329486
???:
C25H25ClN6O
??? ??:
460.97
MOL ??:
23491-45-4.mol
MSDS ??:
SDS

Hoechst 33258 ??

???
314 °C
??
1.5099 (rough estimate)
???
1.6300 (estimate)
?? ??
-20°C
???
H2O: 10 mg/mL
??? ??
??
??
????? ?? ??? ?????
???
??
BRN
4088183
???
???
InChIKey
UDJDXLXTHZQAAC-UHFFFAOYSA-N
SMILES
CN1CCN(C2C=CC3NC(C4C=CC5NC(C6C=CC(O)=CC=6)=NC=5C=4)=NC=3C=2)CC1.Cl
CAS ??????
23491-45-4(CAS DataBase Reference)
EPA
Phenol, 4-[5-(4-methyl-1-piperazinyl)[2,5'-bi-1H-benzimidazol]-2'-yl]-, trihydrochloride (23491-45-4)
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
??? ?? Xn
?? ???? ?? 22-36/38-36/37/38-20/21/22
????? 26-36-24/25-23
WGK ?? 3
RTECS ?? SM1140500
F ?????? 3-8-10
TSCA TSCA listed
HS ?? 32129000
???? ??? 11 - Combustible Solids
?? dog,LD,intravenous,> 22400ug/kg (22.4mg/kg),LUNGS, THORAX, OR RESPIRATION: DYSPNEASENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYEGASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS,National Technical Information Service. Vol. PB84-171206,
????(GHS): Exclamation Mark (GHS07)
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H302 ??? ??? ?? ?? ?? - ?? ?? 4 ?? P264, P270, P301+P312, P330, P501
H315 ??? ??? ??? ????? ?? ????? ?? 2 ?? P264, P280, P302+P352, P321,P332+P313, P362
H319 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 2A ?? P264, P280, P305+P351+P338,P337+P313P
??????:
P305+P351+P338 ?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.
NFPA 704
0
2 0

Hoechst 33258 MSDS


p-(5-(5-(4-Methyl-1-piperazinyl)-1H-2-benzimidazolyl)-1H-2-benzimidazolyl)phenol trihydrochloride

Hoechst 33258 C??? ??, ??, ??

??? ??

yellow to yellow-green powder

??

Hoechst 33258 is useful for staining DNA, chromosomes and nuclei. The nucleic acid binds to the minor groove of DNA at AT-rich sequences. This dye is commonly used for determining the DNA content of viable cells without detergent treatment or fixation and for fluorescence

?? ??

Membrane-permeable, adenine-thymine-specific fluorescent stain. Useful for staining DNA, chromosomes, and nuclei. Increases the rate of channel-mediated Ca2+ efflux from junctional cytoplasmic reticulum vesicles. Can also be used to detect mycoplasma contamination in tissue culture. H 33258 and the related compound H 33342 (Cat. No. 382065) have been used in conjunction with RNA aptamers in the 5′ untranslated region (UTR) to control expression of transfected gene constructs.

Hoechst 33258 ?? ?? ? ???

???

?? ??


Hoechst 33258 ?? ??

???( 379)?? ??
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Hoechst 33258 ?? ??:

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