Vanadinocene Dichloride
|
|
Vanadinocene Dichloride ??
- ???
- 182-194 °C (dec.)(lit.)
- ??
- 1,6 g/cm3
- ?? ??
- 2-8°C
- ???
- soluble in H2O, chloroform, ethanol
- ??? ??
- ?? ??
- Specific Gravity
- 1.6
- ??
- ??
- ???
- ?? ??
- ??
- Air & Moisture Sensitive
- ?? ??
- NIOSH: Ceiling 0.05 mg/m3
- InChI
- 1S/2C5H5.2ClH.V/c2*1-2-4-5-3-1;;;/h2*1-5H;2*1H;/q;;;;+2/p-2
- InChIKey
- MDWJZZZKWHLMQP-UHFFFAOYSA-L
- SMILES
- Cl[V]Cl.[CH]1[CH][CH][CH][CH]1.[CH]2[CH][CH][CH][CH]2
- CAS ??????
- 12083-48-6(CAS DataBase Reference)
??
- ?? ? ?? ??
- ?? ? ???? ?? (GHS)
| ??? ?? | T | ||
|---|---|---|---|
| ?? ???? ?? | 25-36/37/38 | ||
| ????? | 26-28-36/37/39-45 | ||
| ????(UN No.) | UN 3285 6.1/PG 3 | ||
| WGK ?? | 3 | ||
| RTECS ?? | YW1580000 | ||
| ?? ?? | 8 | ||
| ???? | II | ||
| HS ?? | 29310099 | ||
| ???? ??? | 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects |
||
| Hazard Classifications | Acute Tox. 3 Oral Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
Vanadinocene Dichloride C??? ??, ??, ??
??? ??
dark green crystalline powder??
Vanadocene dichloride is used like other metallocenes as a catalyst, ultraviolet absorber, reducing agent, free radical scavenger, antiknock agent in gasoline, and as a developmental anticancer drug.?? ??
Pale green crystals or green powder.??? ?? ??
Extremely sensitive to exposure to air. Also extremely sensitive to moisture; decomposes in water?? ???
Organometallics, such as BIS(CYCLOPENTADIENYL)VANADIUM DICHLORIDE, are reactive with many other groups. Incompatible with acids and bases. Organometallics are good reducing agents and therefore incompatible with oxidizing agents. Often reactive with water to generate toxic or flammable gases. Organometallics containing halogens (fluorine, chlorine, bromine, iodine) bonded to the metal typically with generate gaseous hydrohalic acids (HF, HCl, HBr, HI) with water.????
Flash point data for BIS(CYCLOPENTADIENYL)VANADIUM DICHLORIDE are not available. BIS(CYCLOPENTADIENYL)VANADIUM DICHLORIDE is probably combustible.Pharmaceutical Applications
Vanadocene dichloride [( η5-C5H5)2VCl2, dichloro bis(η5-cyclopentadienyl)vanadium(IV)] is structurally very similar to Cp2TiCl2. It also consists of a metal centre with an oxidation number of +IV, in this case vanadium, and two Cp and two chloride ligands. Vanadocene dichloride is a 17-electron complex containing an unpaired electron and is therefore paramagnetic .Vanadocene dichloride has found application as a catalyst for polymerisation reactions, but was also intensively studied as an anticancer agent in parallel to Cp2TiCl2 because of their structural similarities. Vanadocene dichloride has proven to be even more effective than its titanium analogue as an antiproliferative agent against both animal and human cell lines in preclinical testing. The main problems are the difficult characterisation of the active vanadium compounds and their fast hydrolysis.
Vanadinocene Dichloride ?? ?? ? ???
???
?? ??
Vanadinocene Dichloride ?? ??
???( 72)?? ??
| ??? | ?? | ??? | ?? | ?? ? | ?? |
|---|---|---|---|---|---|
| CONIER CHEM AND PHARMA LIMITED | |
sales@conier.com | China | 49979 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +86-13203830695 |
laboratory@coreychem.com | China | 30224 | 58 |
| Xi'an MC Biotech, Co., Ltd. | 029-89275612 +8618991951683 |
mcbio_sales@163.com | China | 2251 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-81139210 +86-17392587031 |
1059@dideu.com | China | 9996 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 17705817739 |
info@dycnchem.com | China | 52704 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +86-17732866630 |
mina@chuanghaibio.com | China | 18126 | 58 |
| PT CHEM GROUP LIMITED | +86-85511178; +86-85511178 |
peter68@ptchemgroup.com | China | 35425 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +86-571-86217390; +8618058761490 |
info@gihichemicals.com | China | 49895 | 58 |
| XIAMEN AMITY INDUSTRY AND TRADE CO., LTD. | +8618950047208 |
ellena@amitychem.com | China | 43414 | 58 |
| Mainchem Co., Ltd. | +86-0592-6210733 |
sale@mainchem.com | China | 32343 | 55 |