5H-???[b,f]???
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![5H-???[b,f]???](CAS/GIF/256-96-2.gif)
5H-???[b,f]??? ??
- ???
- 197 °C
- ?? ?
- 221 °C(lit.)
- ??
- 1.290 g/mL at 20 °C(lit.)
- ???
- n
20/D 1.523(lit.)
- ???
- >230 °F
- ?? ??
- Keep in dark place,Sealed in dry,Room Temperature
- ???
- ???: 50mg/mL, ??
- ??? ??
- ??
- ?? ?? (pKa)
- 1.71±0.20(Predicted)
- ??
- ????? ?????
- ???
- ?? ?????(25 mg/ml), ?(??), ???, ????? ? DMSO? ?????.
- BRN
- 1343358
- InChI
- 1S/C14H11N/c1-3-7-13-11(5-1)9-10-12-6-2-4-8-14(12)15-13/h1-10,15H
- InChIKey
- LCGTWRLJTMHIQZ-UHFFFAOYSA-N
- SMILES
- N1c2ccccc2C=Cc3ccccc13
- LogP
- 4.06
- CAS ??????
- 256-96-2(CAS DataBase Reference)
??
- ?? ? ?? ??
- ?? ? ???? ?? (GHS)
| ??? ?? | C,Xi,N,Xn | ||
|---|---|---|---|
| ?? ???? ?? | 34-51/53-22-36/37/38 | ||
| ????? | 26-36/37/39-45-61-27-24/25 | ||
| ????(UN No.) | UN 3265 8/PG 2 | ||
| WGK ?? | 3 | ||
| F ?????? | 10-21 | ||
| ?? ?? ?? | Irritant | ||
| HS ?? | 29339900 | ||
| ???? ??? | 11 - Combustible Solids | ||
| Hazard Classifications | Acute Tox. 4 Oral Aquatic Chronic 2 |
5H-???[b,f]??? C??? ??, ??, ??
??? ??
Yellow to orange-yellow fine powder??
Iminostilbene is mainly used as a pharmaceutical intermediate for the production of carbamazepine, Oxcarbazepine, and rhodium catalyst ligand. It is a metabolite of of carbamazepine which is used primarily in the treatment of epilepsy and neuropathic pain.?? ??
iminostilbene synthesis: 10,11-Dihydro-5-dibenz(b,f)azepine [Iminodibenzyl, 494-19-9] as raw material was acylated by triphosgene, after bromination by bromine and dehydrobromination, reacted with sodium hydroxide in isopropanol to give Iminostilbene.??
ChEBI: Iminostilbene is a mancude organic heterotricyclic parent that consists of a seven-membered nitrogen hetrocycle fused with two benzene rings. It has a role as a marine xenobiotic metabolite. It is a mancude organic heterotricyclic parent and a dibenzoazepine.?? ??
Iminostilbene has good antioxidant effects. N-acetyl iminostilbene was synthesized by incubating iminostilbene (2.0020 g, 10.360 mmol) with acetic anhydride.?? ??
5H-Dibenz[b,f]azepine, a tricyclic amine with a seven-membered ring, is commonly known as iminostilbene. It is used as an intermediate or a starting material in the synthesis of many anticonvulsant drugs.It is also used as a starting material to prepare pharmacologically important dibenzoazepine-pyridazine derivatives and synthesize olefinic multidentate ligand, which is used to prepare Rh(I) complexes.5H-???[b,f]??? ?? ?? ? ???
???
Diphenyl
Aza
2-[(E)-2-?????]???
10,11-?????-5H-???[b,f]???-10-o
1-(5H-???[b,f]???-5-?)???
?? T-?????
??????
??????
?? ??
5H-???[b,f]??? ?? ??
???( 354)?? ??
| ??? | ?? | ??? | ?? | ?? ? | ?? |
|---|---|---|---|---|---|
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5H-???[b,f]??? ?? ??:
??? ????????? ??????? ??? ??? ?????? 10-????????? ?? 1,3,5-???????
Iminodiacetonitrile
Iminodibenzyl
OPIPRAMOL DIHYDROCHLORIDE
5-Cyano-5H-dibenz[b,f]azepine
Amezepine
Dibenz[b,f]azepine-5-carbonyl chloride
Depramine
2,2'-IMINOSTILBENE
10-Methoxy Iminostilbene Carbonylchloride
OPIPRAMOL
3-Hydroxy Carbamazepine