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?? ??? ??>(6R-trans)-7-amino-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio]methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
(6R-trans)-7-amino-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio]methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
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(6R-trans)-7-amino-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio]methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid ??? ???
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- ?? ??:
- 58909-56-1
- ???:
- (6R-trans)-7-amino-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio]methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
- ???(??):
- 7(R)-amino-3-[[(2,5-dihydro-6-hydroxy-2-methyl-5-oxo-1,2,4-triazin-3-yl)thio]methyl]-3-cephem-4-carboxylic acid;Einecs 261-491-7;Ceftriaxone IMpurity E;Ceftriaxone EP Impurity E;Nicotinamide Impurity 170;7-AMINOCEPHALOSPORANIC TRIAZINE;Ceftriaxone Sodium Ep Impurity E;Ceftriaxone Impurity E USP/EP/BP;Ceftriaxone Sodium USP Impurity F;Ceftriaxone EP Impurity E Monomer
- CBNumber:
- CB8896623
- ???:
- C12H13N5O5S2
- ??? ??:
- 371.39
- MOL ??:
- 58909-56-1.mol
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(6R-trans)-7-amino-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio]methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid ??
- ?? ?
- 718℃[at 101 325 Pa]
- ??
- 2.03±0.1 g/cm3(Predicted)
- ???
- 0Pa at 25℃
- ?? ?? (pKa)
- 2.49±0.50(Predicted)
- ???
- 200mg/L at 20℃
- LogP
- -3.5 at 20℃
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- ?? ? ?? ??
- ?? ? ???? ?? (GHS)
| ????(GHS): |
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Danger |
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P- ?? |
| H317 |
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?? 1 |
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P261, P272, P280, P302+P352,P333+P313, P321, P363, P501 |
| H334 |
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?? 1 |
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P261, P285, P304+P341, P342+P311,P501 |
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| ??????: |
| P261 |
??·?·??·???·??·...·????? ??? ????. |
| P272 |
??? ??? ??? ??? ???? ???. |
| P280 |
????/???/???/?????? ?????. |
| P285 |
??? ? ?? ?? ???? ??? ???? ????? |
| P302+P352 |
??? ??? ??? ?? ????. |
| P304+P341 |
???? ??,??? ??? ?? ??? ??? ??? ?? ??? ??? ???? ?? ??? ??? ??? ? |
| P321 |
(…) ??? ???. |
| P333+P313 |
????? ?? ??? ???? ???? ??·??? ????. |
| P342+P311 |
??? ??? ???? ????(??)? ??? ????. |
| P363 |
?? ??? ??? ??? ?????. |
| P501 |
...? ??? / ??? ?? ???. |
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(6R-trans)-7-amino-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio]methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid C??? ??, ??, ??
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An intermediate in the synthesis of cephalosporin antibiotics, Ceftriaxone (C245000) and Cefixime (C242800).
(6R-trans)-7-amino-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio]methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid ?? ?? ? ???
???
?? ??
(6R-trans)-7-amino-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio]methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid ?? ??
???( 67)?? ??
(6R-trans)-7-amino-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio]methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid ?? ??:
