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- ???
- 198°, also reported as mp 191-193° (lower melting form, mp 158°)
- ?? ?
- 280.42°C (rough estimate)
- ??
- 1.1832 (rough estimate)
- ???
- 1.4880 (estimate)
- ?? ?? (pKa)
- 11.63±0.46(Predicted)
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| ?? | LD50 in rats (mg/kg): 2500 orally; 900 i.p. (Pindell) |
|---|
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Originator
Nostyn,Ames,US,1956Manufacturing Process
54 g of carbromal (2-bromo-2-ethylbutyryl-urea) in 600 cc of isopropanol was stirred and refluxed for 3 hours with 27.8 g of anhydrous silver oxide. The reaction mixture was filtered and the silver residue was extracted with 100 cc of boiling isopropanol. The filtered and dried solids which separated weighed 22.5 g and melted at 189°C to 190.5°C. Concentration of the filtrate yielded an additional 3.3 g of product which melted at 160°C to 170°C. These two crops were separately obtained as white needles by crystallization from alcohol and exhibited slight solubility in water. The first crop gave 21.7 g of 2- ethyl-cis-crotonyl urea with a melting point of 191°C to 193°C, and the second crop gave 0.9 g with a melting point of 191°C to 193°C for a total yield of 42.4 g or 63% of the theoretical.Therapeutic Function
Sedative???? ?? ?? ? ???
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| ??? | ?? | ??? | ?? | ?? ? | ?? |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 |
marketing@targetmol.com | United States | 32467 | 58 |
| Shaanxi Didu New Materials Co. Ltd | +86-86-17392712697 +8617792793228 |
1069@dideu.com | China | 8662 | 58 |
| LGC Science (Shanghai) Ltd. | 17717235263 |
fan.yang@LGCgroup.com | China | 18796 | 58 |
| Baoji Didu Pharmaceutical and Chemical Co., Ltd | 029-81145305 17791533577 |
1021@dideu.com | China | 9996 | 58 |
| TargetMol Chemicals Inc. | 15002134094 |
marketing@targetmol.cn | China | 29867 | 58 |
| Biosynth Biological Technology (Suzhou) Co Ltd | -- |
sales@biosynth.com | China | 6051 | 58 |
???? ?? ??:
Ectoine
[[4-[2-[[(3-Ethyl-2,5-dihydro-4-methyl-2-oxo-1H-pyrrol-1-yl)carbonyl]amino]ethyl]phenyl]sulfonyl]-carbamic acid ethyl ester
3-Ethyl-2,5-Dihydro-4-Methyl-2-Oxo-N-(2-Phenylethyl)-1h-Pyrrole-1-Carboxamide
Homeostan
ectylurea
rac trans-Hydroxy Glimepiride-D5
4-[2-[(3-Ethyl-4-methyl-2-oxo-3-pyrrolin-1-yl)carboxamido]ethyl]benzenesulfonamide
Glimepiride