ChemicalBook >?? ???? >?????

?????

????? ??? ???

?? ??:: 1879-77-2

???:: ?????

???(??):: ?????

???:: doxibetasol

???(??):: doxibetasol;21-Deoxy Betamethasone;βmethasone Valerate EP Impurity B;Betamethasone Valerate EP Impurity B;9-Fluoro-16-methylpregna-1,4-diene-11,17-diol-3,20-dione;9-Fluoro-11,17-dihydroxy-16-methylpregna-1,4-diene-3,20-dione;Betamethasone Valerate EP Impurity B (21-Deoxy Betamethasone);16β-methyl-9α-fluoro-11β,17α-dihydroxy-1,4-pregnadiene-3,20-dione;16β-Methyl-11β,17-dihydroxy-9-fluoro-5α-pregnane-1,4-diene-3,20-dione;Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17-dihydroxy-16-methyl-, (11β,16β)-

CBNumber:: CB8917054

???:: C22H29FO4

??? ??:: 376.465

MOL ??:: 1879-77-2.mol

?? ?? 33

????? ??

???: 232-234 °C(Solv: chloroform (67-66-3))

?? ?: 527.1±50.0 °C(Predicted)

??: 1.25±0.1 g/cm3(Predicted)

???: ???(?? ???), ?????(?? ???), DMSO(?? ???), ???(?? ???)

??? ??: ??

??? ??: ??? ??

?? ?? (pKa): 12.52±0.70(Predicted)

??: ???? ?? ???

?? ? ?? ??
?? ? ???? ?? (GHS)

????(GHS):

?? ?:

Warning

??·?? ??:

??	??·?? ??	?? ??	??	?? ?	P- ??
H302	??? ???	?? ?? ?? - ??	?? 4	??	P264, P270, P301+P312, P330, P501
H315	??? ??? ???	????? ?? ?????	?? 2	??	P264, P280, P302+P352, P321,P332+P313, P362
H319	?? ?? ??? ???	?? ? ?? ?? ??? ??	?? 2A	??	P264, P280, P305+P351+P338,P337+P313P
H335	?? ???? ??? ? ??	?? ???? ?? - 1? ??;???? ??	?? 3	??

??????:

P280	????/???/???/?????? ?????.
P305+P351+P338	?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.

????? C??? ??, ??, ??

??

Doxybetasol (Betamethasone Valerate EP Impurity B) is an impurity of Betamethasone (B327000), which is a glucocorticoid used as an anti-inflammatory agent.

????? ?? ?? ? ???

???

?? ??

????? ?? ??

???( 33)?? ??

???	??	???	??	?? ?	??
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????? ?? ??:

????? ????, ??? ????? ????? ??? ??? Betamethasone Valerate EP Impurity F Halometasone Flumethasone-17-acetate DEXAMETHASONE SODIUM PHOSPHATE Flumethasone Flumethasone 21-pivalate 9-Fluoro-11b,17,21-trihydroxy-16a-methylpregna-1,4-diene-3,20-dione 17-valerate doxibetasol dexamethasone 21-methanesulfonate dexamethasone 21-pivalate 9-fluoro-11beta,17,21-trihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione 17,21-di(propionate) DEXAMETHASONE HEMISUCCINATE 1,4-PREGNADIEN-9ALPHA-FLUORO-16ALPHA-METHYL-11BETA, 17ALPHA, 21-TRIOL 3,20-DIONE 21-T-BUTYLACETATE DEXAMETHASONE, [6,7-3H(N)] 6-BETA-HYDROXYDEXAMETHASONE

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