ChemicalBook >?? ???? >?????
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????? ??
- ???
- 156-160 °C
- ??
- D23 -33° (22.5 mg in 5 ml chloroform)
- ?? ?
- 463.29°C (rough estimate)
- ??
- 0.98±0.1 g/cm3 (20 ºC 760 Torr)
- ???
- 1.5100 (estimate)
- ?? ??
- -20°C
- ???
- ?????(???? ??), ???(?? ???, ??? ??)
- ??? ??
- ?? ??
- ?? ?? (pKa)
- 15.03±0.70(Predicted)
- ??
- ???
- ???? ??
- Glycine max (soybean)
- Merck
- 13,1736
- BRN
- 3216975
- InChIKey
- SGNBVLSWZMBQTH-ZRUUVFCLSA-N
- SMILES
- [H][C@@]12CC=C3C[C@@H](O)CC[C@]3(C)[C@@]1([H])CC[C@]4(C)[C@H](CC[C@@]24[H])[C@H](C)CC[C@H](C)C(C)C
- LogP
- 9.972 (est)
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- ?? ? ?? ??
- ?? ? ???? ?? (GHS)
| ??? ?? | Xn,T | ||
|---|---|---|---|
| ?? ???? ?? | 20/21/22-36/37/38-48/20/22-40-38-22 | ||
| ????? | 26-36-45-36/37/39-23 | ||
| ????(UN No.) | UN 1888 6.1/PG 3 | ||
| WGK ?? | 3 | ||
| HS ?? | 29061990 | ||
| ???? ??? | 11 - Combustible Solids | ||
| Hazard Classifications | Acute Tox. 4 Dermal Acute Tox. 4 Inhalation Acute Tox. 4 Oral Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
| ????(GHS): |
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24α-methyl Cholesterol is a phytosterol found in vegetables, fruits, nuts, and seeds that competitively inhibits the absorption of intestinal cholesterol and decreases the transcription of genes important for cholesterol metabolism. The cholesterol lowering effects of phytosterols, such as 24α-methyl cholesterol, have been reported to be beneficial for lowering the incidence of atherosclerotic plaques. 24α-methyl Cholesterol can also act as an agonist at liver X receptors (LXR) and, through activation of LXR signaling, has been shown to suppress the proliferation of prostate and breast cancer cells.??? ??
White Solid??
Campesterol may be used as a plant sterol to test its effect on the transcriptional activation of liver X receptor α (LXRA) in breast cancer cells. It may also be used as a sterol standard for calibration curve generation in liquid chromatography multiple reaction monitoring (LC-MRM) analysis.?? ??
Campesterol is a plant sterol, which is an analog of cholesterol and a brassinosteroid (BR) precursor. The enzyme diminute/dwarf1 mediates the synthesis of campesterol from 24-methylenecholesterol. Campesterol possesses methyl group at C-24 position of the side chain in the cholesterol structure.Purification Methods
Campesterol is recrystallised twice from hexane and once from Me2CO. The benzoyl derivative has m 158-160o [] D 23 -8.6o (CHCl3), and the acetyl derivative has m 137138o (EtOH) and [] D 23 -35.1o (c 2.9, CHCl3) [Fernholz & MacPhillamy J Am Chem Soc 6 3 1155 1941]. [Beilstein 6 III 2680.]????? ?? ?? ? ???
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Campesterol,?95+％,CAMPESTEROL(P),CAMPESTEROL 1X1ML CHLOROFORM 100UG/ML
beta-Sitosterol
Campesterol-25,26,26,26,27,27,27-D7
CAMPESTEROL-D3
7-Campesterol
Campesteryl-D-glucoside
Campesteryl-D-glucoside-6’-palmitate
Campesteryl palmitate
Campesteryl ferulate
Δ8-Campesterol
7-KETO-BETA-CAMPESTEROL
7-ALPHA-HYDROXY-BETA-CAMPESTEROL
Campesterol (24-methyl-D3)
DELTA7-CAMPESTEROL
campesterol acetate
5,6-DIHYDROXY-BETA-CAMPESTEROL
5,6-ALPHA/BETA-EPOXY-BETA-CAMPESTEROL