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Cinepazide

Cinepazide ??? ???

?? ??:: 23887-46-9

???:: Cinepazide

???(??):: CINEPAZIDE;NSC 291562;Cinepazide free base;Cinepazide USP/EP/BP;1-(pyrrolidin-1-ylcarbonylmethyl)-4-(3,4,5-trimethoxycinnamoyl)piperazine;1-(1-Pyrrolidinylcarbonylmethyl)-4-[3-(3,4,5-trimethoxyphenyl)acryloyl]piperazine;1-[(1-Pyrrolidinylcarbonyl)methyl]-4-[1-oxo-3-(3,4,5-trimethoxyphenyl)-2-propenyl]piperazine;PIPERAZINE,1-[2-OXO-2-(1-PYRROLIDINYL)ETHYL]-4-[1-OXO-3-(3,4,5-TRIMETHOXYPHENYL)-2-PROPENYL];2-Propen-1-one, 1-[4-[2-oxo-2-(1-pyrrolidinyl)ethyl]-1-piperazinyl]-3-(3,4,5-trimethoxyphenyl)-

CBNumber:: CB9365720

???:: C22H31N3O5

??? ??:: 417.5

MOL ??:: 23887-46-9.mol

?? ?? 65

Cinepazide ??

?? ?: 637.8±55.0 °C(Predicted)

??: 1.200±0.06 g/cm3(Predicted)

?? ??: Store at -20°C

???: DMSO? ???

?? ?? (pKa): 5.22±0.10(Predicted)

CAS ??????: 23887-46-9(CAS DataBase Reference)

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Cinepazide C??? ??, ??, ??

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Cinepazide is an injection in the treatment of acute myocardial infarction and its effect on serum inflammatory factors.

World Health Organization (WHO)

Cinepazide, a vasodilating agent, was first introduced into medicine in 1974. It is used in the treatment of peripheral and cerebral vascular disorders. Following reports of blood dyscrasias, including agranulocytosis and thrombocytopenia, associated with the use of the drug, the Spanish Committee on Drug Surveillance has recommended its withdrawal. In other countries, the approved product information of preparations containing cinepazide has been amended to include a relevant warning on these adverse effects.

Cinepazide ?? ?? ? ???

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3',4',5'-trimethoxycinnamoyl chloride 1-((????-1-????)??)????

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Cinepazide ?? ??

???( 65)?? ??

???	??	???	??	?? ?	??
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Cinepazide ?? ??:

2-????-3-(4-?????)-2-???? ??? ??????????? ??????? P-???? ???? 4-Methoxybenzoic acid 4-Methoxycinnamic acid Ethyl 4-methoxycinnamate 1-((PYRROLIDINE-1-CARBONYL)METHYL)PIPERAZINE 1-(2-PYRROLIDINOETHYL)PIPERAZINE CINEPAZIDE MALEATE Cintramide 1-[4-(2-AMINOETHYL)PIPERAZIN-1-YL]ETHANONE N,N-DIETHYL-2-PIPERAZIN-1-YL-ACETAMIDE 1-CINNAMOYL-PIPERAZINE Cinepazide 1-[3-(4-HYDROXY-3-METHOXYPHENYL)-OXO-2-PROPENYL]-PIPERAZINE

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