ChemicalBook >?? ???? >DPDPE
DPDPE
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DPDPE ??
- ?? ?
- 1038.6±65.0 °C(predicted)
- ??
- 1.38±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
- RTECS ??
- YV9461100
- ?? ??
- −20°C
- ???
- Water:10.0(Max Conc. mg/mL);0.15(Max Conc. mM)
- ??? ??
- ??
- ??? ??
- ??? ??
- ?? ?? (pKa)
- 2.97±0.70(predicted)
- ??
- White to off-white
- ???
- Soluble to 1 mg/ml in water
- ???
- Tyr-{Pen}-Gly-Phe-{Pen} (Disulfide bridge:Pen2-Pen5)
- InChIKey
- MCMMCRYPQBNCPH-WMIMKTLMSA-N
- SMILES
- S1SC([C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C1(C)C)C(=O)O)Cc3ccccc3)NC(=O)[C@@H](N)Cc2ccc(cc2)O)(C)C
??
| WGK ?? | 3 | ||
|---|---|---|---|
| ???? ??? | 11 - Combustible Solids |
DPDPE C??? ??, ??, ??
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[D-Pen2,5]-Enkephalin hydrate (DPDPE) has been used to study the pharmacodynamic and pharmacokinetic capabilities of polyethylene glycol (PEG) conjugate of DPDPE in rodents. It has been used to study the tendency of opiate self-administration in male Long-Evans rats, in ventral tegmental area (VTA).??
ChEBI: A heterodetic cyclic peptide that is a cyclic enkephalin analogue, having D-penicillaminyl residues located at positions 2 and 5, which form the heterocycle via a disulfide bond.?? ??
[D-Pen2,5]-Enkephalin hydrate, also called DPDPE, is a peptide and acts as a δ1-opioid receptor agonist. Opioid receptors are divided into three types called, μ, κ and δ, depending upon their ligands. These ligands are peptides and are classified as enkephalins, endorphins and dynorphins.DPDPE ?? ?? ? ???
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DPDPE ?? ??
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