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L-????

L-????
L-???? ??? ???
?? ??:
13073-35-3
???:
L-????
???(??):
L-????
???:
L-ETHIONINE
???(??):
S-ethyl-L-homocysteine;H-ETH-OH;Nsc82393;L-ETHIONINE;l-butyricaci;L-Ethionine>L-ETHIONINE 98+%;L -ETHIONINE 99%;s-ethyl-homocystein;L-Ethionine
CBNumber:
CB9426830
???:
C6H13NO2S
??? ??:
163.24
MOL ??:
13073-35-3.mol
MSDS ??:
SDS

L-???? ??

???
280 °C (dec.)(lit.)
??
D24 +25.1°; D23 +20.1° (1N HCl) (Armstrong, Lewis)
??
1.085 (estimate)
???
22 ° (C=1, 1mol/L HCl)
?? ??
Keep in dark place,Sealed in dry,2-8°C
???
?? ???(??), ?(??) ? ???
??? ??
??
??? ??
??? ??
?? ?
310.4±37.0 °C(Predicted)
?? ?? (pKa)
2.23±0.10(Predicted)
??
???? ?????
?? ??
22.068°(C=0.01g/ml 1N HCL)
Merck
14,3738
InChI
1S/C6H13NO2S/c1-2-10-4-3-5(7)6(8)9/h5H,2-4,7H2,1H3,(H,8,9)/t5-/m0/s1
InChIKey
GGLZPLKKBSSKCX-YFKPBYRVSA-N
SMILES
CCSCC[C@H](N)C(O)=O
CAS ??????
13073-35-3(CAS DataBase Reference)
EPA
L-Ethionine (13073-35-3)
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
??? ?? Xi
?? ???? ?? 36/37/38
????? 26
WGK ?? 3
RTECS ?? ES6825300
TSCA TSCA listed
HS ?? 2930.90.4950
???? ??? 11 - Combustible Solids
Hazard Classifications Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
?? ?? ??? 13073-35-3(Hazardous Substances Data)
?? rat,LD,intraperitoneal,> 1gm/kg (1000mg/kg),LIVER: OTHER CHANGESLIVER: CHANGES IN LIVER WEIGHT,Acta Pathologica Japonica. Vol. 39, Pg. 281, 1989.
????(GHS): Exclamation Mark (GHS07)
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H315 ??? ??? ??? ????? ?? ????? ?? 2 ?? P264, P280, P302+P352, P321,P332+P313, P362
H319 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 2A ?? P264, P280, P305+P351+P338,P337+P313P
H335 ?? ???? ??? ? ?? ?? ???? ?? - 1? ??;???? ?? ?? 3 ??
??????:
P261 ??·?·??·???·??·...·????? ??? ????.
P264 ?? ??? ?? ??? ????.
P264 ?? ??? ?? ??? ????.
P271 ?? ?? ??? ? ?? ???? ?????.
P280 ????/???/???/?????? ?????.
P302+P352 ??? ??? ??? ?? ????.
P305+P351+P338 ?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.
NFPA 704
0
2 0

L-???? C??? ??, ??, ??

??? ??

White Solid

??

Ethionine-induced inhibition of protein synthesis and lowering of ATP level in the liver.

??

ChEBI: An S-ethylhomocysteine that has S-configuration at the chiral centre.

Purification Methods

Likely impurities are N-acetyl-(R and S)-ethionine, S-methionine, and R-ethionine. Crystallise it from water by adding 4volumes of EtOH or 85% aqueous EtOH. It sublimes at 196-216o/0.3mm with 99.1% recovery and unracemised [Gross & Gradsky J Am Chem Soc 77 1678 1955]. [Weiss & Stekol J Am Chem Soc 73 2399 1951, Greenstein & Winitz The Chemistry of the Amino Acids J. Wiley, Vol 3 pp 2658, 2659 1961, Beilstein 4 IV 3194.]

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