DEGUELIN
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DEGUELIN ??
- ???
- 85-87 °C(lit.)
- ??
- D27 -97.2° (c = 0.2 in benzene)
- ?? ?
- 560.1±50.0 °C(Predicted)
- ??
- 1+-.0.06 g/cm3(Predicted)
- ?? ??
- -20°C
- ???
- DMSO: >10mg/mL
- ??? ??
- ??
- ??? ??
- ??? ??
- ??
- ???? ?????
- ?? ??
- [α]/D -70 to -80°, c = 0.2 in methanol
- ???
- ??? ?? ?????? 2? ?? ??????. DMSO ?? ??? ??? -20°?? ?? 3?? ?? ??? ? ????.
- InChI
- 1S/C23H22O6/c1-23(2)8-7-12-15(29-23)6-5-13-21(24)20-14-9-17(25-3)18(26-4)10-16(14)27-11-19(20)28-22(12)13/h5-10,19-20H,11H2,1-4H3/t19-,20+/m1/s1
- InChIKey
- ORDAZKGHSNRHTD-UXHICEINSA-N
- SMILES
- COc1cc2OC[C@H]3Oc4c(ccc5OC(C)(C)C=Cc45)C(=O)[C@H]3c2cc1OC
??
- ?? ? ?? ??
- ?? ? ???? ?? (GHS)
| ????? | 22-24/25 | ||
|---|---|---|---|
| WGK ?? | 3 | ||
| RTECS ?? | DX1500000 | ||
| HS ?? | 29329990 | ||
| ???? ??? | 11 - Combustible Solids |
| ????(GHS): |
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| ?? ?: | Warning | ||||||||||||||||||||||||||||||||
| ??·?? ??: |
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DEGUELIN C??? ??, ??, ??
??
Rotenoids, deriving from the flavonoid family of compounds, act as chemopreventive agents that inhibit NADH:ubiquinone oxidoreductase activity and suppress phorbol ester-??
Deguelin exhibits potent apoptotic and antiangiogenic activities in a variety of transformed cells and cancer cells. Deguelin also exhibits potent tumor suppressive effects in xenograft tumor models for many human cancers.???? ??
Anticancer and antiviral agent; chemopreventive and pro-apoptotic. Inhibits phorbol ester-induced ornithine decarboxylase and NADH:ubiquinone oxidoreductase activities (IC 50 values are 11 and 6.9 nM respectively). Inhibits PI 3-kinase and reduces pAkt levels in pre-malignant and malignant human bronchial epithelial cells. Active in vivo .DEGUELIN ?? ?? ? ???
???
[1]Benzopyrano[3,4-b][1]benzopyran-12(6H)-one, 6a,12a-dihydro-9-hydroxy-2,3-dimethoxy-8-(3-methyl-2-buten-1-yl)-, (6aS,12aS)-
Phenylselenenyl chloride
??? ??
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DEGUELIN ?? ??
???( 193)?? ??
| ??? | ?? | ??? | ?? | ?? ? | ?? |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 33024 | 60 |
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 |
zheyansh@163.com | CHINA | 3619 | 58 |
| Chengdu GLP biotechnology Co Ltd | 028-87075086 13350802083 |
scglp@glp-china.com | CHINA | 1824 | 58 |
| Chengdu Biopurify Phytochemicals Ltd. | +86-28-82633860; +8618080483897 |
sales@biopurify.com | China | 4616 | 58 |
| BOC Sciences | +1-631-485-4226 |
inquiry@bocsci.com | United States | 19936 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 |
sales@conier.com | China | 49979 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 |
factory@coreychem.com | China | 29792 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-87569266 +86-17392581500 |
1015@dideu.com | China | 3991 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 |
marketing@targetmol.com | United States | 32466 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 |
sales@tnjchem.com | China | 34563 | 58 |
DEGUELIN ?? ??:
NS-398
Indometacin
Piroxicam
(S)-(+)-Ibuprofen
Saw Palmetto P.E
Elm bark extract
Heartleaf Houttuynia P.E.
Meloxicam
Rotenone
N-(2-PHENYLETHYL)-INDOMETHACIN AMIDE
Equol
4'-METHOXY-2-P-METHOXYPHENYLBUTYROPHENONE
DEGUELIN
1-(2,4-Dihydroxyphenyl)-2-(3,4-dimethoxyphenyl)ethanone
2,5-DIMETHOXYPHENYLACETONE
METHYLEUGENOLGLYCOL
5-HYDROXY-2,2-DIMETHYL-2H-CHROMENE-6-CARBALDEHYDE
(2,4,5-TRIMETHOXYPHENYL)ACETALDEHYDE