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Betahistine mesylate

Betahistine mesylate ??? ???
?? ??:
54856-23-4
???:
Betahistine mesylate
???(??):
BETAHISTINE MESILATE;TENYL;Melopat;Extovyl;Aequamen;Merislon;NSC44059;NSC 44059;NSC-44059;Meginalisk
CBNumber:
CB9713565
???:
C8H12N2.2CH4O3S
??? ??:
328.41
MOL ??:
54856-23-4.mol
MSDS ??:
SDS

Betahistine mesylate ??

???
112°C
?? ??
Keep in dark place,Inert atmosphere,Room temperature
???
?? ?? ? ??, ???(96%)? ? ???, 2-?????? ?? ?? ????.
??? ??
Solid
??
???? ?????
???
?? ???
???
???
?? ??
???(???)
InChI
InChI=1S/C8H12N2.2CH4O3S/c1-9-7-5-8-4-2-3-6-10-8;2*1-5(2,3)4/h2-4,6,9H,5,7H2,1H3;2*1H3,(H,2,3,4)
InChIKey
ZBJJDYGJCNTNTH-UHFFFAOYSA-N
SMILES
C1(CCNC)N=CC=CC=1.S(=O)(=O)(O)C.S(=O)(=O)(O)C
CAS ??????
54856-23-4(CAS DataBase Reference)
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
WGK ?? WGK 3
RTECS ?? UT2970200
HS ?? 2933.39.9200
???? ??? 11 - Combustible Solids
?? LD50 orl-rat: 3030 mg/kg NIIRDN 6,750,82
????(GHS): Flame (GHS02)
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H226 ??? ?? ? ?? ??? ?? ?? 3 ??
??????:
P210 ?·???·??·????? ????? - ?? ???.
P233 ??? ??? ?????. ??? ??? ? ?? ?? ??? ???? ?????.
P240 ??? ????? ?? ? ??????.
P241 ?? ??? ??[???/??/??/...]?(?) ?????.
P242 ???? ???? ?? ??? ?????
P243 ??? ?? ??? ????.
P280 ????/???/???/?????? ?????.
P303+P361+P353 ??(?? ????)? ??? ??? ?? ??? ??? ????? ??? ?? ????/?????.
P370+P378 ?? ? ?? ?? ?? (Section 5. ??, ??? ????? ??? ???)?(?) ?????.
P403+P235 ??? ? ?? ?? ???? ???? ?????.
P501 ...? ??? / ??? ?? ???.

Betahistine mesylate C??? ??, ??, ??

??? ??

White or almost white, crystalline powder, very hygroscopic.

??

Vasodilatator;H1 agonist
Betahistine mesylate is an orally active histamine H1 receptor agonist and a H3 receptor antagonist. Betahistine mesylate is used for the study of rheumatoid arthritis (RA).

??

Betahistine mesylate is a histamine analog and H1 receptor agonist that serves as a vasodilator. It is used in MENIERE DISEASE and in vascular headaches but may exacerbate bronchial asthma and peptic ulcers.

Indications

Betahistine mesylate is the mesylate salt form of Betahistine, a histamine analog and H3 receptor agonist that serves as a vasodilator. It is used in MENIERE DISEASE and in vascular headaches but may exacerbate bronchial asthma and peptic ulcers.

Safety Profile

Poison by subcutaneous route.Moderately toxic by ingestion and other routes. Whenheated to decomposition it emits toxic fumes of NOx andSOx.

Betahistine mesylate ?? ?? ? ???

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?? ??


Betahistine mesylate ?? ??

???( 253)?? ??
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Betahistine mesylate ?? ??:

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