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???????? ??? ???
?? ??:
36304-84-4
???:
????????
???(??):
????????
???:
Dimemorfan phosphate
???(??):
dimemorphan phosphate;Hofvan;Astomin;Dimemomin;DIMEMORFAN PHOSPHATE;Dimemorfan phosphate USP/EP/BP;dimemorphanpChemicalbookhosphate;Morphinan,3,17-dimethyl-,(9α,13α,14α)-,phosphate(1:1);Morphinan, 3,17-dimethyl-, (9α,13α,14α)-, phosphate (1:1);inhibit,Inhibitor,Sigma Receptor,Dimemorfan phosphate,Dimemorfan
CBNumber:
CB9832947
???:
C18H25N.H3O4P
??? ??:
353.396
MOL ??:
36304-84-4.mol

???????? ??

???
267-269°
??
D23 +25.7° (c = 0.5 in methanol)
?? ??
Store at -20°C
???
Water : 20 mg/mL (56.59 mM);DMSO : 1 mg/mL (2.83 mM)
??? ??
Solid
??
White to off-white

??

?? LD50 in mice (mg/kg): 223 s.c.; 475 orally (Kasé)

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Originator

Astomin,Yamanouchi Pharmaceutical Co., Ltd.

Therapeutic Function

Antitussive

Safety Profile

Poison by intravenous, intraperitoneal, and subcutaneous routes. Moderately toxic by ingestion. An experimental teratogen. Experimental reproductive effects. Used as an antitussive agent. When heated to decomposition it emits very toxic fumes of NOx and POx.

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