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ChemicalBook >> CAS DataBase List >>Aminopterin

Aminopterin suppliers

Aminopterin

CAS:
54-62-6
MF:
C19H20N8O5
MW:
440.41

Properties

Melting point:
225 °C
alpha 
18 º (c=1% in 0.1N NaOH)
Boiling point:
551.67°C (rough estimate)
Density 
1.4378 (rough estimate)
refractive index 
1.6910 (estimate)
Flash point:
87℃
storage temp. 
-20°C
solubility 
2 M NaOH: 50 mg/mL
form 
powder
pka
pKa 5.5 (Uncertain)
color 
yellow
biological source
synthetic (organic)
Water Solubility 
10mL/vial, clear, red (in TC Medium)
ε(extinction coefficient)
24,500 at 282nm in 0.1 M NaOH at 1M
25,700 at 261nm in 0.1 M NaOH at 1M
8,100 at 373nm in 0.1 M NaOH at 1M
Merck 
14,472
BRN 
69045
InChIKey
TVZGACDUOSZQKY-UHFFFAOYSA-N
SMILES
OC(CC[C@@H](C(O)=O)NC(C1=CC=C(NCC2=NC3=C(N)N=C(N)N=C3N=C2)C=C1)=O)=O
CAS DataBase Reference
54-62-6(CAS DataBase Reference)
EPA Substance Registry System
Aminopterin (54-62-6)

Safety Information

Symbol(GHS) 
Skull and Crossbones (GHS06)Health Hazard (GHS08)
GHS06,GHS08
Signal word 
Danger
Hazard statements 
H300-H360
Precautionary statements 
P201-P280-P301+P330+P331+P310-P308+P313
Hazard Codes 
T+
Risk Statements 
61-28-63-26/27/28
Safety Statements 
53-28-36/37-45-36/37/39-22
RIDADR 
UN 2811 6.1/PG 1
WGK Germany 
3
RTECS 
MA1050000
8-10-23
TSCA 
TSCA listed
HazardClass 
6.1(a)
PackingGroup 
I
HS Code 
29339900
Storage Class
6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects
Hazard Classifications
Acute Tox. 3 Oral
Muta. 2
Repr. 1B
Hazardous Substances Data
54-62-6(Hazardous Substances Data)
Toxicity
LDLo orl-rat: 2500 mg/kg JPETAB 95,303,49

Use

Aminopterin is used as antineoplastic, antirheumatic, folic acid antagonist. Its actively transported into cells by thefolate transporter. In the cell, its converted to a high molecular weight polyglutamate metabolite by folylpolyglutamate synthase, that, in turn, binds to dihydrofolate reductase and inhibits its activity.

178 supplier list of "Aminopterin"

  • Product Name:Aminopterin
  • Products Intro:Purity: 98% | Package: 1g,10g,25g,100g,500g,1kg
  • Company Type: Trader
  • Country/Region: CHINA
  • Main Products: 528-94-9,AMMONIUM SALICYLATE,Linolenic acid,463-40-1,931-36-2
  • Product Name:aminopterin
  • Products Intro:Purity: 99% | Package: 1kg
  • Company Type: Trader
  • Country/Region: CHINA
  • Product Name:Aminopterin
  • Products Intro:Purity: 99% | Package: 1g
  • Company Type: Trader
  • Country/Region: CHINA
Aminopterin Aminopterin 2Photos

$39.00-100.00

  • Product Name:Aminopterin
  • Products Intro:Purity: >=95% | Package: 5mg;41USD|10mg;66USD|25mg;132USD | CustNote: REAGENT;FOR LABORATORY USE ONLY
  • Company Type: Trader
  • Country/Region: UNITED STATES
  • Main Products: Compound Libraries,Noval Small Molecucles,Nature Compounds,Inhibitory Antibodies,Life science Kits
  • Product Name:Aminopterinum
  • Company Type: Reagent
  • Country/Region: CHINA
  • Main Products: Gamma-butyrolactone
  • Product Name:Aminopterin
  • Products Intro:Purity: 99.9%|Package: 1g
  • Company Type: Trader
  • Country/Region: CHINA
  • Product Name:AMINOPTERIN
  • Products Intro:Purity: 99% | Package: USP EP CP
  • Company Type: Trader
  • Country/Region: CHINA
  • Main Products: Pharmceutical,Optical Brightening,dyes
  • Product Name:Aminopterin
  • Products Intro:Purity: 0.98 | Package: 1KG
  • Company Type: Trader
  • Country/Region: CHINA
  • Main Products: API(Active Pharmaceutical Ingredient),Lab Fine Chemical,Phytochemistry,Cosmetic Raw Materials
  • Product Name:Methotrexate EP Impurity B
  • Products Intro:Purity: > 95% | Package: 500 mg | CustNote: Please reach out to us for more information about custom solutions.
  • Company Type: Reagent
  • Country/Region: UNITED STATES
  • Product Name:Aminopterin
  • Products Intro:Purity: 0.95&0.99 | Package: 0.1KG;1KG;1000KG | CustNote: Top Quality
  • Company Type: Trader
  • Country/Region: CHINA
  • Main Products: Triglycol monomethyl ether, CAS 112-35-6,Tetrafluoro-1-propanol, CAS 76-37-9,Aminoacetaldehyde dimethyl acetal, CAS 22483-09-6,Hexachloroethane, CAS 67-72-1,3-Allyloxy-2-Hydroxy-1-Propane,Sodium Salt, CAS 52556-42-0
You can find Aminopterin suppliers, manufacturers, and distributors from countries such as CHINA, United States and the United Kingdom here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.

Aminopterin Related Search:

Triamterene6-Aminocaproic acidAcetaminophenL-Glutamic acidMethylparabenBenzoyl peroxide2-Amino-4-hydroxy-1H-pteridineBensulfuron methyl MethotrexateL-Glutamic acid, N-[4-[[ (2-amino-1, 4-dihydro-4-oxo-6-pteridinyl)meth yl]methylamino]benzoyl]-4-[Methyl[(2-amino-4-hydroxypteridine)-6-ylmethyl]amino]benzoic acidGlycine2,4-DIAMINO-6-(HYDROXYMETHYL)PTERIDINEMethyl6-(Bromomethyl)-2,4-pteridinediamine hydrobromideN-(4-(METHYLAMINO)BENZOYL)-L-GLUTAMIC ACIDMethotrexate Related Compound E (50 mg) (4-{[(2,4-Diaminopteridin-6-yl)methyl](methyl)amino}benzoic acid, hemihydrochloride)Glutamic acid
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