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ChemicalBook >> CAS DataBase List >>IWR-1-endo

IWR-1-endo suppliers

IWR-1-endo

CAS:
1127442-82-3
MF:
C25H19N3O3
MW:
409.44

Properties

alpha 
-3.0~+3.0°(20℃/D)(c=0.1,CH3CN)
Boiling point:
643.9±55.0 °C(Predicted)
Density 
1.425±0.06 g/cm3(Predicted)
storage temp. 
room temp
solubility 
DMSO: soluble5mg/mL, clear
form 
Liquid
pka
11.88±0.43(Predicted)
color 
white to beige
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
InChIKey
ZGSXEXBYLJIOGF-ALFLXDJESA-N
SMILES
N4(C(=O)[C@@H]5[C@@H]([C@H]6C[C@@H]5C=C6)C4=O)c1ccc(cc1)C(=O)Nc2c3ncccc3ccc2

Safety Information

Symbol(GHS) 
Exclamation Mark (GHS07)
GHS07
Signal word 
Warning
Hazard statements 
H302
Precautionary statements 
P280-P305+P351+P338
WGK Germany 
3
Storage Class
10 - Combustible liquids

Use

IWR-1-endo act as inhibitors of Wnt response. It appear that IWR compounds induce stabilization of Axin proteins via a direct interaction, which is a part of the b-catenin destruction complex (consists of Apc, Axin, Ck1 and Gsk3b). Such compounds may be used in the treatment of Wnt protein signaling-related diseases and conditions such as cancer, degenerative diseases, type II diabetes and osteopetrosi s.

107 supplier list of "IWR-1-endo"

  • Product Name:IWR-1-endo
  • Products Intro:Purity: >98% | Package: 25 mg | CustNote: Please reach out to us for more information about custom solutions.
  • Company Type: Trader
  • Country/Region: UNITED STATES
  • Product Name:IWR-1-endo
  • Products Intro:Purity: 99% | Package: 1KG
  • Company Type: Trader
  • Country/Region: CHINA
IWR-1 IWR-1 2Photos

$50.00-168.00

  • Product Name:IWR-1
  • Products Intro:Purity: 99.82% | Package: 5mg;50USD|10mg;76USD|25mg;168USD | CustNote: REAGENT;FOR LABORATORY USE ONLY
  • Company Type: Trader
  • Country/Region: UNITED STATES
  • Main Products: Compound Libraries,Noval Small Molecucles,Nature Compounds,Inhibitory Antibodies,Life science Kits
  • Product Name:IWR-1-endo
  • Products Intro:Purity: 99.9% | Package: 25kgs/Drum;200kgs/Drum | CustNote: FDA GMP CEP Approved Manufacturer
  • Company Type: Trader
  • Country/Region: CHINA
  • Product Name:IWR-1
  • Products Intro:Purity: 99% | Package: 5KG;1KG | CustNote: IWR-1
  • Company Type: Trader
  • Country/Region: CHINA
  • Main Products: sarms
  • Product Name:IWR-1
  • Company Type: Trader
  • Country/Region: CHINA
  • Main Products: Fine Chemical,API,Raw Material,Pharmaceutical Compounds,Others
  • Product Name:IWR-1-endo
  • Products Intro:Purity: 0 | Package: 1g; 5g; 25g; 1kg; 5kg; 25kg | CustNote: 0
  • Company Type: Trader
  • Country/Region: CHINA
  • Main Products: Pharmaceutical intermediate
  • Product Name:IWR-1
  • Products Intro:Purity: >=98% | Package: $64.9/5mg;$98.9/10mg;$449.9/50mg;Bulk package | CustNote: 98%
  • Company Type: Trader
  • Country/Region: UNITED STATES
  • Main Products: Chemicals and BioChemicals,Materials Science,ligands acting on targets,Proteins,Antibodies
  • Product Name:endo-IWR 1
  • Products Intro:Purity: 0.97 | Package: mgs,gs,kgs | CustNote: A894529
  • Company Type: Reagent
  • Country/Region: CHINA
  • 10 mg$149.00
    50 mg$629.00
  • Product Name:[(3aR*,4S*,7R*,7aS)-1,3,3a,4,7,7a-Hexahydro-1,3-dioxo-4,7-methano-2H-isoindol-2-yl]-N-8-quinolinylbenzamide
  • Products Intro:Brand: Tocris Bioscience | Product Number: 3532 | Purity: ≥98% (HPLC)
  • Company Type: Trader
  • Country/Region: UNITED KINGDOM
  • Main Products: Hypromellose,1,4-Di-tert-butyl-2,5-dimethoxybenzene,Di(propylene glycol) methyl ether acetate,n-Dodecylphosphonic acid,Bis-Aminopropyl Diglycol Dimaleate
You can find IWR-1-endo suppliers, manufacturers, and distributors from countries such as CHINA, United States and the United Kingdom here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.

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