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ChemicalBook >> CAS DataBase List >> 3-(2-chloropyriMidin-4-yl)-1-Methylindole

3-(2-chloropyriMidin-4-yl)-1-Methylindole

$9 - $890
Product name: 3-(2-chloropyriMidin-4-yl)-1-Methylindole
CAS: 1032452-86-0
MF: C13H10ClN3
MW: 243.69
EINECS:806-155-8
MDL Number:MFCD26397861
Synonyms:3-(2-chloropyriMidin-4-yl)-1-Methylindole;elagolix intermediate 11;EOS-61220;3-(2-Chloro-4-pyrimidyl)-1-methylindole;3-(2-Chloro-4-pyrimidinyl)-1-methyl-1H-indole ，98%;1H-Indole, 3-(2-chloro-4-pyrimidinyl)-1-methyl-;-(2-Chloropyrimidin-4-yl)-1-Methylindole;3- (2-chloro-4-pyridine) -1-methyl indole

Price24 Properties Safety Information Description

24 prices

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Brand

aablocks
AccelPharmtech
Ambeed
American Custom Chemicals Corporation
Chemenu
Crysdot
Synthonix
TRC

Package

5MG
100mg
1g
5g
10G
25g
100g
500g
1KG

Manufactureraablocks
Product numberAA003967
Product description3-(2-Chloropyrimidin-4-yl)-1-methyl-1H-indole 98%
Packaging100g
Price$92
Updated2026-05-28
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Manufactureraablocks
Product numberAA003967
Product description3-(2-Chloropyrimidin-4-yl)-1-methyl-1H-indole 98%
Packaging25g
Price$30
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA003967
Product description3-(2-Chloropyrimidin-4-yl)-1-methyl-1H-indole ≥97%
Packaging5g
Price$11
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA003967
Product description3-(2-Chloropyrimidin-4-yl)-1-methyl-1H-indole ≥97%
Packaging1g
Price$10
Updated2026-05-28
Buy

ManufacturerAccelPharmtech
Product numberXP1529
Product description3-(2-chloropyriMidin-4-yl)-1-Methyl-1H-indole 99.00%
Packaging10G
Price$120
Updated2026-05-21
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ManufacturerAccelPharmtech
Product numberXP1529
Product description3-(2-chloropyriMidin-4-yl)-1-Methyl-1H-indole 99.00%
Packaging1KG
Price$890
Updated2026-05-21
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ManufacturerAmbeed
Product numberA104126
Product description3-(2-Chloropyrimidin-4-yl)-1-methyl-1H-indole 98%
Packaging100g
Price$128
Updated2021-12-16
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ManufacturerAmbeed
Product numberA104126
Product description3-(2-Chloropyrimidin-4-yl)-1-methyl-1H-indole 98%
Packaging1g
Price$9
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA104126
Product description3-(2-Chloropyrimidin-4-yl)-1-methyl-1H-indole 98%
Packaging5g
Price$19
Updated2021-12-16
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ManufacturerAmbeed
Product numberA104126
Product description3-(2-Chloropyrimidin-4-yl)-1-methyl-1H-indole 98%
Packaging10g
Price$32
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA104126
Product description3-(2-Chloropyrimidin-4-yl)-1-methyl-1H-indole 98%
Packaging25g
Price$39
Updated2021-12-16
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ManufacturerAmerican Custom Chemicals Corporation
Product numberHCH0620635
Product description3-(2-CHLOROPYRIMIDIN-4-YL)-1-METHYLINDOLE 95.00%
Packaging5MG
Price$505.3
Updated2021-12-16
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ManufacturerChemenu
Product numberCM105137
Product description3-(2-chloropyrimidin-4-yl)-1-methyl-1H-indole 95%+
Packaging500g
Price$468
Updated2021-12-16
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ManufacturerChemenu
Product numberCM105137
Product description3-(2-chloropyrimidin-4-yl)-1-methyl-1H-indole 95%+
Packaging100g
Price$139
Updated2026-05-26
Buy

ManufacturerChemenu
Product numberCM105137
Product description3-(2-chloropyrimidin-4-yl)-1-methyl-1H-indole 95%+
Packaging100g
Price$139
Updated2026-05-20
Buy

ManufacturerChemenu
Product numberCM105137
Product description3-(2-chloropyrimidin-4-yl)-1-methyl-1H-indole 95%+
Packaging100g
Price$122
Updated2021-12-16
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
aablocks	AA003967	3-(2-Chloropyrimidin-4-yl)-1-methyl-1H-indole 98%	100g	$92	2026-05-28	Buy
aablocks	AA003967	3-(2-Chloropyrimidin-4-yl)-1-methyl-1H-indole 98%	25g	$30	2026-05-28	Buy
aablocks	AA003967	3-(2-Chloropyrimidin-4-yl)-1-methyl-1H-indole ≥97%	5g	$11	2026-05-28	Buy
aablocks	AA003967	3-(2-Chloropyrimidin-4-yl)-1-methyl-1H-indole ≥97%	1g	$10	2026-05-28	Buy
AccelPharmtech	XP1529	3-(2-chloropyriMidin-4-yl)-1-Methyl-1H-indole 99.00%	10G	$120	2026-05-21	Buy
AccelPharmtech	XP1529	3-(2-chloropyriMidin-4-yl)-1-Methyl-1H-indole 99.00%	1KG	$890	2026-05-21	Buy
Ambeed	A104126	3-(2-Chloropyrimidin-4-yl)-1-methyl-1H-indole 98%	100g	$128	2021-12-16	Buy
Ambeed	A104126	3-(2-Chloropyrimidin-4-yl)-1-methyl-1H-indole 98%	1g	$9	2021-12-16	Buy
Ambeed	A104126	3-(2-Chloropyrimidin-4-yl)-1-methyl-1H-indole 98%	5g	$19	2021-12-16	Buy
Ambeed	A104126	3-(2-Chloropyrimidin-4-yl)-1-methyl-1H-indole 98%	10g	$32	2021-12-16	Buy
Ambeed	A104126	3-(2-Chloropyrimidin-4-yl)-1-methyl-1H-indole 98%	25g	$39	2021-12-16	Buy
American Custom Chemicals Corporation	HCH0620635	3-(2-CHLOROPYRIMIDIN-4-YL)-1-METHYLINDOLE 95.00%	5MG	$505.3	2021-12-16	Buy
Chemenu	CM105137	3-(2-chloropyrimidin-4-yl)-1-methyl-1H-indole 95%+	500g	$468	2021-12-16	Buy
Chemenu	CM105137	3-(2-chloropyrimidin-4-yl)-1-methyl-1H-indole 95%+	100g	$139	2026-05-26	Buy
Chemenu	CM105137	3-(2-chloropyrimidin-4-yl)-1-methyl-1H-indole 95%+	100g	$139	2026-05-20	Buy
Chemenu	CM105137	3-(2-chloropyrimidin-4-yl)-1-methyl-1H-indole 95%+	100g	$122	2021-12-16	Buy

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Properties

Melting point :201 °C (decomp)(Solvent: Acetonitrile; Water)
Boiling point :486.3±28.0 °C(Predicted)
Density :1.31±0.1 g/cm3(Predicted)
storage temp. :under inert gas (nitrogen or Argon) at 2-8°C
pka :-0.89±0.31(Predicted)
Appearance :Off-white to light yellow Solid
InChI :InChI=1S/C13H10ClN3/c1-17-8-10(9-4-2-3-5-12(9)17)11-6-7-15-13(14)16-11/h2-8H,1H3
InChIKey :IIBWXYHPBMUNJP-UHFFFAOYSA-N
SMILES :N1(C)C2=C(C=CC=C2)C(C2C=CN=C(Cl)N=2)=C1

Safety Information

Symbol(GHS):

Signal word:

Warning

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	P-Codes
H302	Harmful if swallowed	Acute toxicity,oral	Category 4	Warning	P264, P270, P301+P312, P330, P501
H315	Causes skin irritation	Skin corrosion/irritation	Category 2	Warning	P264, P280, P302+P352, P321,P332+P313, P362
H319	Causes serious eye irritation	Serious eye damage/eye irritation	Category 2A	Warning	P264, P280, P305+P351+P338,P337+P313P
H335	May cause respiratory irritation	Specific target organ toxicity, single exposure;Respiratory tract irritation	Category 3	Warning

Precautionary statements:

P264	Wash hands thoroughly after handling.
P264	Wash skin thouroughly after handling.
P270	Do not eat, drink or smoke when using this product.
P280	Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312	IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352	IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321	Specific treatment (see … on this label).
P330	Rinse mouth.
P332+P313	IF SKIN irritation occurs: Get medical advice/attention.
P362	Take off contaminated clothing and wash before reuse.
P501	Dispose of contents/container to..…

Description

3-(2-Chloropyrimidin-4-yl)-1-methylindole is a key intermediate in the synthesis of Osimertinib Mesylate. Osimertinib Mesylate (Trade Name: Tagrisso) is a targeted anticancer drug developed by AstraZeneca. It received marketing approval from the U.S. Food and Drug Administration (FDA) on November 13, 2015, and from the European Medicines Agency (EMA) on February 2, 2016, respectively. Later, it was also approved for marketing by the Pharmaceuticals and Medical Devices Agency (PMDA) of Japan on March 28, 2016. This medication is indicated for the treatment of non-small cell lung cancer (NSCLC) positive for the EGFR-T790M mutation.

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Suppliers and manufacturers

Jiangsu Magic Biotechnology Co., Ltd

3-(2-chloropyriMidin-4-yl)-1-Methylindole CAS:1032452-86-0

Henan Fengda Chemical Co., Ltd

3-(2-chloropyriMidin-4-yl)-1-Methylindole CAS:1032452-86-0

Apeloa production Co.,Limited

$1.00
3-(2-Chloropyrimidin-4-yl)-1-Methylindole CAS:1032452-86-0

Hefei Lbao Physical & Chemical Science Co.,Ltd

3-(2-chloropyriMidin-4-yl)-1-Methylindole CAS:1032452-86-0

JiangXi Bobert Imp&Exp Co.,LTD

Shandong Dinghao Biological Technology Co. LTD

Capot Chemical Co.,Ltd.

Shanghai Daken Advanced Materials Co.,Ltd

Nanjing Gold Pharmaceutical Technology Co. Ltd.

Beijing Cooperate Pharmaceutical Co.,Ltd

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3-(2-chloropyriMidin-4-yl)-1-Methylindole

Properties

Safety Information

Description

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