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ChemicalBook >> CAS DataBase List >> CALMODULIN-DEPENDENT PROTEIN KINASE II (290-309)

CALMODULIN-DEPENDENT PROTEIN KINASE II (290-309)

CALMODULIN-DEPENDENT PROTEIN KINASE II (290-309) price.
  • $150 - $1784.8
  • Product name: CALMODULIN-DEPENDENT PROTEIN KINASE II (290-309)
  • CAS: 115044-69-4
  • MF: C103H185N31O24S
  • MW: 2273.83
  • EINECS:
  • MDL Number:MFCD00076719
  • Synonyms:CALMODULIN-DEPENDENT PROTEIN KINASE II FRAGMENT 290-309;CAM KINASE II (290-309);H-LEU-LYS-LYS-PHE-ASN-ALA-ARG-ARG-LYS-LEU-LYS-GLY-ALA-ILE-LEU-THR-THR-MET-LEU-ALA-OH;CALMODULIN-DEPENDENT PROTEIN KINASE IIFR AGMENT 290;LEU-LYS-LYS-PHE-ASN-ALA-ARG-ARG-LYS-LEU-LYS-GLY-ALA-ILE-LEU-THR-THR-MET-LEU-ALA;LKKFNARRKLKGAILTTMLA;CA2+/CALMODULIN-DEPENDENT PROTEIN KINASE II (290-309);CALMODULIN DEPENDENT PROTEIN KINASE II
23 prices
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  • aablocks
  • Biorbyt Ltd
  • Biosynth
  • ChemScene
  • Sigma-Aldrich
  • TRC
  • Usbiological
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  • 250ug
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  • 1mg
  • 2mg
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  • Manufactureraablocks
  • Product numberAA000FOD
  • Product descriptionCaM Kinase II (290-309), Calmodulin Antagonist ≥95%
  • Packaging10mg
  • Price$713
  • Updated2026-05-25
  • Buy
  • Manufactureraablocks
  • Product numberAA000FOD
  • Product descriptionCaM Kinase II (290-309), Calmodulin Antagonist ≥95%
  • Packaging5mg
  • Price$514
  • Updated2026-05-25
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  • Manufactureraablocks
  • Product numberAA000FOD
  • Product descriptionCaM Kinase II (290-309), Calmodulin Antagonist ≥95%
  • Packaging1mg
  • Price$214
  • Updated2026-05-25
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  • ManufacturerBiorbyt Ltd
  • Product numberorb364464
  • Product descriptionCalmodulin-Dependent Protein Kinase II (290-309) > 95%
  • Packaging1mg
  • Price$462.4
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb364464
  • Product descriptionCalmodulin-Dependent Protein Kinase II (290-309) > 95%
  • Packaging5mg
  • Price$979.2
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb364464
  • Product descriptionCalmodulin-Dependent Protein Kinase II (290-309) > 95%
  • Packaging10mg
  • Price$1462
  • Updated2021-12-16
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  • ManufacturerBiosynth
  • Product numberFC110422
  • Product descriptionCalmodulin-Dependent Protein Kinase II (290-309) H-Leu-Lys-Lys-Phe-Asn-Ala-Arg-Arg-Lys-Leu-Lys-Gly-Ala-Ile-Leu-Thr-Thr-Met-Leu-Ala-OH
  • Packaging5mg
  • Price$1784.8
  • Updated2021-12-16
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  • ManufacturerBiosynth
  • Product numberFC110422
  • Product descriptionCalmodulin-Dependent Protein Kinase II (290-309)
  • Packaging250mg
  • Price$720
  • Updated2026-06-04
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  • ManufacturerBiosynth
  • Product numberFC110422
  • Product descriptionCalmodulin-Dependent Protein Kinase II (290-309)
  • Packaging100mg
  • Price$542
  • Updated2026-06-04
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  • ManufacturerBiosynth
  • Product numberFC110422
  • Product descriptionCalmodulin-Dependent Protein Kinase II (290-309)
  • Packaging10mg
  • Price$150
  • Updated2026-06-04
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  • ManufacturerBiosynth
  • Product numberFC110422
  • Product descriptionCalmodulin-Dependent Protein Kinase II (290-309) H-Leu-Lys-Lys-Phe-Asn-Ala-Arg-Arg-Lys-Leu-Lys-Gly-Ala-Ile-Leu-Thr-Thr-Met-Leu-Ala-OH
  • Packaging250ug
  • Price$155
  • Updated2021-12-16
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  • ManufacturerBiosynth
  • Product numberFC110422
  • Product descriptionCalmodulin-Dependent Protein Kinase II (290-309)
  • Packaging25mg
  • Price$225
  • Updated2026-06-04
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  • ManufacturerBiosynth
  • Product numberFC110422
  • Product descriptionCalmodulin-Dependent Protein Kinase II (290-309) H-Leu-Lys-Lys-Phe-Asn-Ala-Arg-Arg-Lys-Leu-Lys-Gly-Ala-Ile-Leu-Thr-Thr-Met-Leu-Ala-OH
  • Packaging500ug
  • Price$270
  • Updated2021-12-16
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  • ManufacturerBiosynth
  • Product numberFC110422
  • Product descriptionCalmodulin-Dependent Protein Kinase II (290-309)
  • Packaging50mg
  • Price$360.5
  • Updated2026-06-04
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  • ManufacturerBiosynth
  • Product numberFC110422
  • Product descriptionCalmodulin-Dependent Protein Kinase II (290-309) H-Leu-Lys-Lys-Phe-Asn-Ala-Arg-Arg-Lys-Leu-Lys-Gly-Ala-Ile-Leu-Thr-Thr-Met-Leu-Ala-OH
  • Packaging1mg
  • Price$472
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth
  • Product numberFC110422
  • Product descriptionCalmodulin-Dependent Protein Kinase II (290-309) H-Leu-Lys-Lys-Phe-Asn-Ala-Arg-Arg-Lys-Leu-Lys-Gly-Ala-Ile-Leu-Thr-Thr-Met-Leu-Ala-OH
  • Packaging2mg
  • Price$821
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA000FOD CaM Kinase II (290-309), Calmodulin Antagonist ≥95% 10mg $713 2026-05-25 Buy
aablocks AA000FOD CaM Kinase II (290-309), Calmodulin Antagonist ≥95% 5mg $514 2026-05-25 Buy
aablocks AA000FOD CaM Kinase II (290-309), Calmodulin Antagonist ≥95% 1mg $214 2026-05-25 Buy
Biorbyt Ltd orb364464 Calmodulin-Dependent Protein Kinase II (290-309) > 95% 1mg $462.4 2021-12-16 Buy
Biorbyt Ltd orb364464 Calmodulin-Dependent Protein Kinase II (290-309) > 95% 5mg $979.2 2021-12-16 Buy
Biorbyt Ltd orb364464 Calmodulin-Dependent Protein Kinase II (290-309) > 95% 10mg $1462 2021-12-16 Buy
Biosynth FC110422 Calmodulin-Dependent Protein Kinase II (290-309) H-Leu-Lys-Lys-Phe-Asn-Ala-Arg-Arg-Lys-Leu-Lys-Gly-Ala-Ile-Leu-Thr-Thr-Met-Leu-Ala-OH 5mg $1784.8 2021-12-16 Buy
Biosynth FC110422 Calmodulin-Dependent Protein Kinase II (290-309) 250mg $720 2026-06-04 Buy
Biosynth FC110422 Calmodulin-Dependent Protein Kinase II (290-309) 100mg $542 2026-06-04 Buy
Biosynth FC110422 Calmodulin-Dependent Protein Kinase II (290-309) 10mg $150 2026-06-04 Buy
Biosynth FC110422 Calmodulin-Dependent Protein Kinase II (290-309) H-Leu-Lys-Lys-Phe-Asn-Ala-Arg-Arg-Lys-Leu-Lys-Gly-Ala-Ile-Leu-Thr-Thr-Met-Leu-Ala-OH 250ug $155 2021-12-16 Buy
Biosynth FC110422 Calmodulin-Dependent Protein Kinase II (290-309) 25mg $225 2026-06-04 Buy
Biosynth FC110422 Calmodulin-Dependent Protein Kinase II (290-309) H-Leu-Lys-Lys-Phe-Asn-Ala-Arg-Arg-Lys-Leu-Lys-Gly-Ala-Ile-Leu-Thr-Thr-Met-Leu-Ala-OH 500ug $270 2021-12-16 Buy
Biosynth FC110422 Calmodulin-Dependent Protein Kinase II (290-309) 50mg $360.5 2026-06-04 Buy
Biosynth FC110422 Calmodulin-Dependent Protein Kinase II (290-309) H-Leu-Lys-Lys-Phe-Asn-Ala-Arg-Arg-Lys-Leu-Lys-Gly-Ala-Ile-Leu-Thr-Thr-Met-Leu-Ala-OH 1mg $472 2021-12-16 Buy
Biosynth FC110422 Calmodulin-Dependent Protein Kinase II (290-309) H-Leu-Lys-Lys-Phe-Asn-Ala-Arg-Arg-Lys-Leu-Lys-Gly-Ala-Ile-Leu-Thr-Thr-Met-Leu-Ala-OH 2mg $821 2021-12-16 Buy

Properties

Density :1.37±0.1 g/cm3(Predicted)
storage temp. :−20°C
solubility :Soluble in DMSO
form :White lyophilized solid
color :white
Water Solubility :water: soluble
Sequence :Leu-Lys-Lys-Phe-Asn-Ala-Arg-Arg-Lys-Leu-Lys-Gly-Ala-Ile-Leu-Thr-Thr-Met-Leu-Ala
InChIKey :LRKHMNPQPYICFK-RBGVSSEXSA-N

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

CaM Kinase II (290-309), Calmodulin Antagonist is a potent, synthetic peptide inhibitor of CaMKII (Ca2+/calmodulin-dependent protein kinase II), which was derived from the cDNA sequence of the rat brain 50-kDa alpha subunit. The use of this inhibitory peptide elucidated the calmodulin binding and inhibitory domains, as well as the initial autophosphorylation site (Thr286) of CaMKII with an IC50 of 52 nM. This peptide product binds CaM (calmodulin) tightly and inhibits additional calmodulin-requiring enzymes, such as PDE (phosphodiesterase) and PP2B (calcineurin). Investigators used this product in STC-1 cells to study the regulation of L-type calcium channels and found the inhibitory peptide to block whole cell calcium currents. Additional research in T84 cells showed that this peptide reduced chloride current by approximately 70% without effect on the channels in parotid acinar cells.

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