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ChemicalBook >> CAS DataBase List >> 12-EPI LEUKOTRIENE B4

12-EPI LEUKOTRIENE B4

12-EPI LEUKOTRIENE B4 price.
  • $155 - $810
  • Product name: 12-EPI LEUKOTRIENE B4
  • CAS: 83709-73-3
  • MF: C20H32O4
  • MW: 336.47
  • EINECS:
  • MDL Number:MFCD00065829
  • Synonyms:12-EPI LEUKOTRIENE B4;5S,12S-DIHYDROXY-6Z,8E,10E,14Z-EICOSATETRAENOIC ACID;(5S,6Z,8E,10E,12S,14Z)-5,12-dihydroxyicosa-6,8,10,14-tetraenoic acid;12(S)-Leukotriene B4;VNYSSYRCGWBHLG-CBBLYLIKSA-N;6,8,10,14-Eicosatetraenoic acid, 5,12-dihydroxy-, (5S,6Z,8E,10E,12S,14Z)-;12-epi Leukotriene B4 (12-epi LTB4)
17 prices
Selected condition:
Brand
  • AHH
  • Arctom
  • Cayman Chemical
  • ChemScene
  • TRC
Package
  • 25μg
  • 50μg
  • 0.0001g
  • 100μg
  • ManufacturerAHH
  • Product numberMT-11695
  • Product description12-EpileukotrieneB4 97%
  • Packaging0.0001g
  • Price$410
  • Updated2021-12-16
  • Buy
  • ManufacturerAHH
  • Product numberMT-11695
  • Product description12-Epileukotriene B4 97%
  • Packaging0.0001g
  • Price$410
  • Updated2026-05-25
  • Buy
  • ManufacturerAHH
  • Product numberMT-11695
  • Product description12-Epileukotriene B4 97%
  • Packaging0.0001g
  • Price$410
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-137350
  • Product description12-epi-LTB4
  • Packaging25μg
  • Price$409
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-137350
  • Product description12-epi-LTB4
  • Packaging50μg
  • Price$711
  • Updated2026-05-26
  • Buy
  • ManufacturerCayman Chemical
  • Product number20135
  • Product description12-epi Leukotriene B4 ≥97%
  • Packaging50μg
  • Price$311
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number20135
  • Product description12-epi Leukotriene B4 ≥97%
  • Packaging100μg
  • Price$646
  • Updated2026-04-30
  • Buy
  • ManufacturerCayman Chemical
  • Product number20135
  • Product description12-epi Leukotriene B4 ≥97%
  • Packaging100μg
  • Price$587
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number20135
  • Product description12-epi Leukotriene B4 ≥97%
  • Packaging50μg
  • Price$343
  • Updated2026-04-30
  • Buy
  • ManufacturerCayman Chemical
  • Product number20135
  • Product description12-epi Leukotriene B4 ≥97%
  • Packaging25μg
  • Price$165
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number20135
  • Product description12-epi Leukotriene B4 ≥97%
  • Packaging25μg
  • Price$182
  • Updated2026-04-30
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0138047
  • Product description12-epi-LTB4
  • Packaging25μg
  • Price$466
  • Updated2026-06-04
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0138047
  • Product description12-epi-LTB4
  • Packaging25μg
  • Price$466
  • Updated2026-06-04
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0138047
  • Product description12-epi-LTB4
  • Packaging50μg
  • Price$810
  • Updated2026-06-04
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0138047
  • Product description12-epi-LTB4
  • Packaging50μg
  • Price$810
  • Updated2026-06-04
  • Buy
  • ManufacturerTRC
  • Product numberL330363
  • Product description12-epiLeukotrieneB4
  • Packaging25μg
  • Price$155
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AHH MT-11695 12-EpileukotrieneB4 97% 0.0001g $410 2021-12-16 Buy
AHH MT-11695 12-Epileukotriene B4 97% 0.0001g $410 2026-05-25 Buy
AHH MT-11695 12-Epileukotriene B4 97% 0.0001g $410 2026-05-26 Buy
Arctom HY-137350 12-epi-LTB4 25μg $409 2026-05-26 Buy
Arctom HY-137350 12-epi-LTB4 50μg $711 2026-05-26 Buy
Cayman Chemical 20135 12-epi Leukotriene B4 ≥97% 50μg $311 2024-03-01 Buy
Cayman Chemical 20135 12-epi Leukotriene B4 ≥97% 100μg $646 2026-04-30 Buy
Cayman Chemical 20135 12-epi Leukotriene B4 ≥97% 100μg $587 2024-03-01 Buy
Cayman Chemical 20135 12-epi Leukotriene B4 ≥97% 50μg $343 2026-04-30 Buy
Cayman Chemical 20135 12-epi Leukotriene B4 ≥97% 25μg $165 2024-03-01 Buy
Cayman Chemical 20135 12-epi Leukotriene B4 ≥97% 25μg $182 2026-04-30 Buy
ChemScene CS-0138047 12-epi-LTB4 25μg $466 2026-06-04 Buy
ChemScene CS-0138047 12-epi-LTB4 25μg $466 2026-06-04 Buy
ChemScene CS-0138047 12-epi-LTB4 50μg $810 2026-06-04 Buy
ChemScene CS-0138047 12-epi-LTB4 50μg $810 2026-06-04 Buy
TRC L330363 12-epiLeukotrieneB4 25μg $155 2021-12-16 Buy

Properties

Boiling point :536.4±50.0 °C(Predicted)
Density :1.040±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C, protect from light
solubility :DMF: 50 mg/ml; DMSO: 50 mg/ml; Ethanol: 50 mg/ml; PBS pH 7.2: 1 mg/ml
pka :4.66±0.10(Predicted)

Safety Information

Symbol(GHS): Flame (GHS02)
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H225 Highly Flammable liquid and vapour Flammable liquids Category 2 Danger P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
Precautionary statements:
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233 Keep container tightly closed.
P240 Ground/bond container and receiving equipment.
P241 Use explosion-proof electrical/ventilating/lighting/…/equipment.
P242 Use only non-sparking tools.
P243 Take precautionary measures against static discharge.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P370+P378 In case of fire: Use … for extinction.
P403+P235 Store in a well-ventilated place. Keep cool.
P501 Dispose of contents/container to..…

Description

Leukotriene B4 (LTB4) compounds are produced by both enzymatic and non-enzymatic processes. The products of enzymatic origin, via Leukotriene A4 (LTA4) hydrolase, are stereospecifically 12(R). Non-enzymatic hydrolysis products are 50:50 mixtures at C-12, but are almost exclusively trans at C-6. Thus, the non-enzymatic hydrolysis product of LTA4 is 6-trans-12-epi LTB4. 12-epi LTB4 is an isomer which would not be expected to occur in either non-enzymatic hydrolysis products, or in the enzymatic products of LTA4 hydrolase. Compared to LTB4, 12-epi LTB4 has significantly reduced activity for the LTB4 receptor on human neutrophils (IC50 of 7.5 mM), and on guinea pig lung membranes with a (Ki of 4.7 mM). 12-epi LTB4 is an weak agonist at both the recombinant human BLT1 and BLT2 receptors, requiring approximately 10 mM for full activation of the receptor.

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