4-[6-[4-(1-Methylethoxy)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]-quinoline
![4-[6-[4-(1-Methylethoxy)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]-quinoline price.](/CAS/GIF/1206711-16-1.gif)
|
- $33 - $1900
- Product name: 4-[6-[4-(1-Methylethoxy)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]-quinoline
- CAS: 1206711-16-1
- MF: C24H20N4O
- MW: 380.44
- EINECS:
- MDL Number:MFCD18384963
- Synonyms:4-[6-[4-(1-Methylethoxy)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]-quinoline;Quinoline, 4-[6-[4-(1-methylethoxy)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]-;4-[6-[4-(1-Methylethoxy)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]quinoline DMH 1;DMH 1 4-[6-[4-(1-Methylethoxy)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]quinoline;4-[6-(4-Isopropoxyphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline;DMH-1, >=98%;4-[6-(4-propan-2-yloxyphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline;DMH-1(VU036482)
82 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- Ambeed
- ApexBio Technology
- Arctom
- Axon Medchem
- Biosynth
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Sigma-Aldrich
- TCI Chemical
- Tocris
- TRC
- Usbiological
Package
- 10mM*1mLinDMSO
- 1mg
- 5mg
- 10
- 10mg
- 10mM*1mLinDMSO(Solution)
- 25mg
- 50mg
- 100mg
- 250mg
- 50
- 10mM*1mLinDMSO(Solid+Solvent)
- 500mg
- 1G
- 10mM(in1mLDMSO)
- 10mM(in 1mL DMSO)
- Manufactureraablocks
- Product numberAA008SQD
- Product descriptionDMH-1 ≥98%
- Packaging5mg
- Price$52
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA008SQD
- Product descriptionDMH-1 99%
- Packaging1mg
- Price$33
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA008SQD
- Product descriptionDMH-1
- Packaging10mg
- Price$88
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA008SQD
- Product descriptionDMH-1
- Packaging25mg
- Price$151
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA008SQD
- Product descriptionDMH-1 99%
- Packaging50mg
- Price$209
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA008SQD
- Product descriptionDMH-1 99%
- Packaging100mg
- Price$320
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA008SQD
- Product descriptionDMH-1 99%
- Packaging250mg
- Price$597
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA008SQD
- Product descriptionDMH-1
- Packaging500mg
- Price$810
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product number10211
- Product descriptionDMH-1 98%
- Packaging100MG
- Price$505
- Updated2026-05-25
- Buy
- ManufacturerACHEMBLOCK
- Product number10211
- Product descriptionDMH-1 98%
- Packaging100MG
- Price$505
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product number10211
- Product descriptionDMH-1 98%
- Packaging25MG
- Price$295
- Updated2026-05-25
- Buy
- ManufacturerACHEMBLOCK
- Product number10211
- Product descriptionDMH-1 98%
- Packaging25MG
- Price$295
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product number10211
- Product descriptionDMH-1 98%
- Packaging1G
- Price$1880
- Updated2026-05-25
- Buy
- ManufacturerACHEMBLOCK
- Product number10211
- Product descriptionDMH-1 98%
- Packaging1G
- Price$1880
- Updated2026-05-27
- Buy
- ManufacturerAmbeed
- Product numberA590459
- Product descriptionDMH-1 99+%
- Packaging1g
- Price$1732
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA590459
- Product descriptionDMH-1 99+%
- Packaging50mg
- Price$256
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA008SQD | DMH-1 ≥98% | 5mg | $52 | 2026-05-28 | Buy |
| aablocks | AA008SQD | DMH-1 99% | 1mg | $33 | 2026-05-28 | Buy |
| aablocks | AA008SQD | DMH-1 | 10mg | $88 | 2026-05-28 | Buy |
| aablocks | AA008SQD | DMH-1 | 25mg | $151 | 2026-05-28 | Buy |
| aablocks | AA008SQD | DMH-1 99% | 50mg | $209 | 2026-05-28 | Buy |
| aablocks | AA008SQD | DMH-1 99% | 100mg | $320 | 2026-05-28 | Buy |
| aablocks | AA008SQD | DMH-1 99% | 250mg | $597 | 2026-05-28 | Buy |
| aablocks | AA008SQD | DMH-1 | 500mg | $810 | 2026-05-28 | Buy |
| ACHEMBLOCK | 10211 | DMH-1 98% | 100MG | $505 | 2026-05-25 | Buy |
| ACHEMBLOCK | 10211 | DMH-1 98% | 100MG | $505 | 2026-05-27 | Buy |
| ACHEMBLOCK | 10211 | DMH-1 98% | 25MG | $295 | 2026-05-25 | Buy |
| ACHEMBLOCK | 10211 | DMH-1 98% | 25MG | $295 | 2026-05-27 | Buy |
| ACHEMBLOCK | 10211 | DMH-1 98% | 1G | $1880 | 2026-05-25 | Buy |
| ACHEMBLOCK | 10211 | DMH-1 98% | 1G | $1880 | 2026-05-27 | Buy |
| Ambeed | A590459 | DMH-1 99+% | 1g | $1732 | 2021-12-16 | Buy |
| Ambeed | A590459 | DMH-1 99+% | 50mg | $256 | 2021-12-16 | Buy |
Properties
Melting point :178 °C
Density :1.24±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble5mg/mL, clear (warmed)
pka :3.34±0.46(Predicted)
form :powder
color :light yellow to orange
InChI :1S/C24H20N4O/c1-16(2)29-19-9-7-17(8-10-19)18-13-26-24-22(14-27-28(24)15-18)20-11-12-25-23-6-4-3-5-21(20)23/h3-16H,1-2H3
InChIKey :JMIFGARJSWXZSH-UHFFFAOYSA-N
SMILES :CC(C)OC(C=C1)=CC=C1C(C=N2)=CN3C2=C(C4=CC=NC5=C4C=CC=C5)C=N3
Density :1.24±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble5mg/mL, clear (warmed)
pka :3.34±0.46(Predicted)
form :powder
color :light yellow to orange
InChI :1S/C24H20N4O/c1-16(2)29-19-9-7-17(8-10-19)18-13-26-24-22(14-27-28(24)15-18)20-11-12-25-23-6-4-3-5-21(20)23/h3-16H,1-2H3
InChIKey :JMIFGARJSWXZSH-UHFFFAOYSA-N
SMILES :CC(C)OC(C=C1)=CC=C1C(C=N2)=CN3C2=C(C4=CC=NC5=C4C=CC=C5)C=N3
Safety Information
| Symbol(GHS): |
|
|||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Signal word: | Warning | |||||||||||||||||||||||||||||||||||
| Hazard statements: |
|
|||||||||||||||||||||||||||||||||||
| Precautionary statements: |
|
Description
Bone morphogenetic proteins (BMP) are secreted signaling proteins, many of which are involved in various developmental processes, in addition to bone formation. DMH1 is an analog of the non-selective BMP receptor inhibitor dorsomorphin that potently inhibits the kinase activity of activin receptor-like kinase 2 (ALK2; IC50 = 13-108 nM). It is much less effective at ALK4, ALK5, AMPK, KDR (VEGFR2) or PDGFRβ, although it inhibits ALK1 and ALK3 at nanomolar concentrations. DMH1 is effective in vivo, as it disrupts dorsoventral development in zebrafish. It also affects stem cell development, increasing cardiomyocyte progenitors and promoting neurogenesis. DMH1 inhibits the growth of lung cancer cells, reducing tumor growth in a xenograft mouse model.More related product prices
LY 2157299 Rapamycin 779353-01-4 SB 431542 BML-275 Y27632 (hydrochloride)Related product price
-
LY 2157299
$13-2822 -
Rapamycin
$9-6160 -
779353-01-4
$28-3728.1
Suppliers and manufacturers
ATK CHEMICAL COMPANY LIMITED
BOC Sciences
HANGZHOU CLAP TECHNOLOGY CO.,LTD
Zhejiang J&C Biological Technology Co.,Limited
InvivoChem
ShenZhen Trendseen Biological Technology Co.,Ltd.
Wuhan Topule Biopharmaceutical Co., Ltd
Zibo Hangyu Biotechnology Development Co., Ltd
![4-[6-[4-(1-Methylethoxy)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]-quinoline](https://img.chemicalbook.com/ProductImageEN/2019-12/small/9f6db54e-092a-41d9-ab18-d369af1d6993.png){kind=small}
