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ChemicalBook >> CAS DataBase List >> 9-(6-Amino-3-pyridinyl)-1-[3-(trifluoromethyl)phenyl]benzo[h]-1,6-naphthyridin-2(1H)-one

9-(6-Amino-3-pyridinyl)-1-[3-(trifluoromethyl)phenyl]benzo[h]-1,6-naphthyridin-2(1H)-one

$65 - $6254
Product name: 9-(6-Amino-3-pyridinyl)-1-[3-(trifluoromethyl)phenyl]benzo[h]-1,6-naphthyridin-2(1H)-one
CAS: 1223001-51-1
MF: C24H15F3N4O
MW: 432.4
EINECS:
MDL Number:MFCD18782652
Synonyms:9-(6-Amino-3-pyridinyl)-1-[3-(trifluoromethyl)phenyl]benzo[h]-1,6-naphthyridin-2(1H)-one;9-(6-AMino-pyridin-3-yl)-...;9-(6-AMino-pyridin-3-yl)-1-(3-trifluoroMethyl-phenyl)-1H-benzo[h][1,6]naphthyridin-2-one;Torin 2, Free Base, >99%;Benzo[h]-1,6-naphthyridin-2(1H)-one, 9-(6-amino-3-pyridinyl)-1-[3-(trifluoromethyl)phenyl]-;9-(6-Amino-3-pyridinyl)-1-[3-(trifluoromethyl)phenyl]benzo[h]-1,6-naphthyridin-2(1H)-one Torin 2;Torin 2 9-(6-Amino-3-pyridinyl)-1-[3-(trifluoromethyl)phenyl]benzo[h]-1,6-naphthyridin-2(1H)-one;9-(6-AMINOPYRIDIN-3-YL)-1-[3-(TRIFLUOROMETHYL)PHENYL]BENZO[H][1,6]NAPHTHYRIDIN-2-ONE

Price74 Properties Safety Information Description

74 prices

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Brand

ACHEMBLOCK
ApexBio Technology
Arctom
Axon Medchem
Biorbyt Ltd
Biosynth
Cayman Chemical
Chemenu
ChemScene
Crysdot
DC Chemicals
Matrix Scientific
Medical Isotopes, Inc.
Sigma-Aldrich
Tocris
TRC
Usbiological

Package

10mM*1mLinDMSO
200mg
10mM*1mLinDMSO(Solution)
200.00mg
50
10
1.00g
10mM*1mLinDMSO(Solid+Solvent)
5mg
10mg
25mg
50mg
100MG
250MG
1G

ManufacturerACHEMBLOCK
Product numberG-5808
Product description9-(6-Amino-pyridin-3-yl)-1-(3-trifluoromethyl-phenyl)-1H-benzo[H][1,6]naphthyridin-2-one 97%
Packaging100MG
Price$235
Updated2026-05-25
Buy

ManufacturerACHEMBLOCK
Product numberG-5808
Product description9-(6-Amino-pyridin-3-yl)-1-(3-trifluoromethyl-phenyl)-1H-benzo[H][1,6]naphthyridin-2-one 97%
Packaging100MG
Price$235
Updated2026-05-27
Buy

ManufacturerACHEMBLOCK
Product numberG-5808
Product description9-(6-Amino-pyridin-3-yl)-1-(3-trifluoromethyl-phenyl)-1H-benzo[H][1,6]naphthyridin-2-one 97%
Packaging250MG
Price$555
Updated2026-05-25
Buy

ManufacturerACHEMBLOCK
Product numberG-5808
Product description9-(6-Amino-pyridin-3-yl)-1-(3-trifluoromethyl-phenyl)-1H-benzo[H][1,6]naphthyridin-2-one 97%
Packaging250MG
Price$555
Updated2026-05-27
Buy

ManufacturerACHEMBLOCK
Product numberG-5808
Product description9-(6-Amino-pyridin-3-yl)-1-(3-trifluoromethyl-phenyl)-1H-benzo[H][1,6]naphthyridin-2-one 97%
Packaging1G
Price$1395
Updated2026-05-25
Buy

ManufacturerACHEMBLOCK
Product numberG-5808
Product description9-(6-Amino-pyridin-3-yl)-1-(3-trifluoromethyl-phenyl)-1H-benzo[H][1,6]naphthyridin-2-one 97%
Packaging1G
Price$1395
Updated2026-05-27
Buy

ManufacturerApexBio Technology
Product numberB1640
Product descriptionTorin2
Packaging50mg
Price$314
Updated2021-12-16
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ManufacturerArctom
Product numberHY-13002
Product descriptionTorin2 99.65%
Packaging25mg
Price$214
Updated2026-05-26
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ManufacturerArctom
Product numberCFN60269
Product descriptionTorin2
Packaging10mg
Price$248
Updated2021-12-16
Buy

ManufacturerArctom
Product numberHY-13002
Product descriptionTorin2 99.65%
Packaging5mg
Price$69
Updated2026-05-26
Buy

ManufacturerArctom
Product numberHY-13002
Product descriptionTorin2 99.65%
Packaging10mM*1mLinDMSO(Solid+Solvent)
Price$72
Updated2026-05-26
Buy

ManufacturerArctom
Product numberHY-13002
Product descriptionTorin2 99.65%
Packaging10mM*1mLinDMSO(Solution)
Price$76
Updated2026-05-26
Buy

ManufacturerArctom
Product numberHY-13002
Product descriptionTorin2 99.65%
Packaging10mg
Price$115
Updated2026-05-26
Buy

ManufacturerArctom
Product numberHY-13002
Product descriptionTorin2 99.65%
Packaging200mg
Price$885
Updated2026-05-26
Buy

ManufacturerArctom
Product numberHY-13002
Product descriptionTorin2 99.65%
Packaging50mg
Price$345
Updated2026-05-26
Buy

ManufacturerArctom
Product numberHY-13002
Product descriptionTorin2 99.65%
Packaging100mg
Price$513
Updated2026-05-26
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
ACHEMBLOCK	G-5808	9-(6-Amino-pyridin-3-yl)-1-(3-trifluoromethyl-phenyl)-1H-benzo[H][1,6]naphthyridin-2-one 97%	100MG	$235	2026-05-25	Buy
ACHEMBLOCK	G-5808	9-(6-Amino-pyridin-3-yl)-1-(3-trifluoromethyl-phenyl)-1H-benzo[H][1,6]naphthyridin-2-one 97%	100MG	$235	2026-05-27	Buy
ACHEMBLOCK	G-5808	9-(6-Amino-pyridin-3-yl)-1-(3-trifluoromethyl-phenyl)-1H-benzo[H][1,6]naphthyridin-2-one 97%	250MG	$555	2026-05-25	Buy
ACHEMBLOCK	G-5808	9-(6-Amino-pyridin-3-yl)-1-(3-trifluoromethyl-phenyl)-1H-benzo[H][1,6]naphthyridin-2-one 97%	250MG	$555	2026-05-27	Buy
ACHEMBLOCK	G-5808	9-(6-Amino-pyridin-3-yl)-1-(3-trifluoromethyl-phenyl)-1H-benzo[H][1,6]naphthyridin-2-one 97%	1G	$1395	2026-05-25	Buy
ACHEMBLOCK	G-5808	9-(6-Amino-pyridin-3-yl)-1-(3-trifluoromethyl-phenyl)-1H-benzo[H][1,6]naphthyridin-2-one 97%	1G	$1395	2026-05-27	Buy
ApexBio Technology	B1640	Torin2	50mg	$314	2021-12-16	Buy
Arctom	HY-13002	Torin2 99.65%	25mg	$214	2026-05-26	Buy
Arctom	CFN60269	Torin2	10mg	$248	2021-12-16	Buy
Arctom	HY-13002	Torin2 99.65%	5mg	$69	2026-05-26	Buy
Arctom	HY-13002	Torin2 99.65%	10mM*1mLinDMSO(Solid+Solvent)	$72	2026-05-26	Buy
Arctom	HY-13002	Torin2 99.65%	10mM*1mLinDMSO(Solution)	$76	2026-05-26	Buy
Arctom	HY-13002	Torin2 99.65%	10mg	$115	2026-05-26	Buy
Arctom	HY-13002	Torin2 99.65%	200mg	$885	2026-05-26	Buy
Arctom	HY-13002	Torin2 99.65%	50mg	$345	2026-05-26	Buy
Arctom	HY-13002	Torin2 99.65%	100mg	$513	2026-05-26	Buy

Next Last

Properties

Melting point :>275° C (dec.)
Boiling point :623.7±55.0 °C(Predicted)
Density :1.427
storage temp. :2-8°C
solubility :Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly, Heated)
form :powder
pka :5.66±0.26(Predicted)
color :white to beige
InChI :InChI=1S/C24H15F3N4O/c25-24(26,27)17-2-1-3-18(11-17)31-22(32)9-6-16-13-29-20-7-4-14(10-19(20)23(16)31)15-5-8-21(28)30-12-15/h1-13H,(H2,28,30)
InChIKey :GUXXEUUYCAYESJ-UHFFFAOYSA-N
SMILES :N1(C2=CC=CC(C(F)(F)F)=C2)C2=C(C=NC3=CC=C(C4=CC=C(N)N=C4)C=C32)C=CC1=O

Safety Information

Symbol(GHS):

Signal word:

Warning

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	P-Codes
H302	Harmful if swallowed	Acute toxicity,oral	Category 4	Warning	P264, P270, P301+P312, P330, P501
H315	Causes skin irritation	Skin corrosion/irritation	Category 2	Warning	P264, P280, P302+P352, P321,P332+P313, P362
H319	Causes serious eye irritation	Serious eye damage/eye irritation	Category 2A	Warning	P264, P280, P305+P351+P338,P337+P313P
H335	May cause respiratory irritation	Specific target organ toxicity, single exposure;Respiratory tract irritation	Category 3	Warning

Precautionary statements:

P261	Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Torin 2 is a potent and selective mTOR inhibitor with IC50 of 0.25 nM in p53?/? MEFs cell line; 800-fold greater selectivity for mTOR than PI3K and improved pharmacokinetic properties. Inhibition of ATM/ATR/DNA-PK with EC50 of 28 nM/35 nM/118 nM,in PC3 cell lines respectively.

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Suppliers and manufacturers

career henan chemical co

$7.00
9-(6-Amino-3-pyridinyl)-1-[3-(trifluoromethyl)phenyl]benzo[h]-1,6-naphthyridin-2(1H)-one CAS:1223001-51-1

ATK CHEMICAL COMPANY LIMITED

Biochempartner

CONIER CHEM AND PHARMA LIMITED

Zhengzhou Alfa Chemical Co.,Ltd

HANGZHOU CLAP TECHNOLOGY CO.,LTD

Dideu Industries Group Limited

Zhejiang J&C Biological Technology Co.,Limited

InvivoChem

ShenZhen Trendseen Biological Technology Co.,Ltd.

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9-(6-Amino-3-pyridinyl)-1-[3-(trifluoromethyl)phenyl]benzo[h]-1,6-naphthyridin-2(1H)-one

Properties

Safety Information

Description

Related product price

Suppliers and manufacturers